Cefazolin sodium: Difference between revisions
Gerald Chi (talk | contribs) mNo edit summary |
|||
| Line 1: | Line 1: | ||
__NOTOC__ | __NOTOC__ | ||
{{Cefazolin sodium}} | {{Cefazolin sodium}} | ||
{{CMG}} | {{CMG}}; {{AE}} {{SS}} | ||
==Overview== | ==Overview== | ||
Cefazolin ([[International Nonproprietary Name|INN]]), also known as cefazoline or cephazolin, is a first generation [[cephalosporin]] [[antibiotic]]. | |||
The drug is usually administrated either by intramuscular injection (injection into a large muscle) or intravenous infusion ([[intravenous]] fluid into a vein). | The drug is usually administrated either by intramuscular injection (injection into a large muscle) or intravenous infusion ([[intravenous]] fluid into a vein). | ||
==Category== | ==Category== | ||
Cephalosporin,First-Generation | |||
Cephalosporin, First-Generation | |||
==US Brand Names== | ==US Brand Names== | ||
ANCEF<sup>®</sup> | ANCEF<sup>®</sup> | ||
==FDA Package Insert== | ==FDA Package Insert== | ||
'''[[Cefazolin sodium description|Description]]''' | |||
''' [[Cefazolin sodium description|Description]]''' | |||
'''| [[Cefazolin sodium clinical pharmacology|Clinical Pharmacology]]''' | '''| [[Cefazolin sodium clinical pharmacology|Clinical Pharmacology]]''' | ||
'''| [[Cefazolin sodium microbiology|Microbiology]]''' | '''| [[Cefazolin sodium microbiology|Microbiology]]''' | ||
| Line 30: | Line 34: | ||
==Mechanism of Action== | ==Mechanism of Action== | ||
Cefazolin sodium belongs to the first-genaration [[Cephalosporins]].[[Cephalosporins]] are bactericidal and have the same mode of action as other beta-lactam antibiotics (such as [[penicillins]]). [[Cephalosporins]] disrupt the synthesis of the [[peptidoglycan ]]layer of bacterial cell walls. The [[peptidoglycan ]]layer is important for cell wall structural integrity, especially in Gram-positive organisms. The final transpeptidation step in the synthesis of the [[peptidoglycan ]]is facilitated by transpeptidases known as [[penicillins]] binding proteins (PBPs) | Cefazolin sodium belongs to the first-genaration [[Cephalosporins]].[[Cephalosporins]] are bactericidal and have the same mode of action as other beta-lactam antibiotics (such as [[penicillins]]). [[Cephalosporins]] disrupt the synthesis of the [[peptidoglycan ]]layer of bacterial cell walls. The [[peptidoglycan ]]layer is important for cell wall structural integrity, especially in Gram-positive organisms. The final transpeptidation step in the synthesis of the [[peptidoglycan ]]is facilitated by transpeptidases known as [[penicillins]] binding proteins (PBPs) | ||
Revision as of 00:18, 6 January 2014
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Sheng Shi, M.D. [2]
Overview
Cefazolin (INN), also known as cefazoline or cephazolin, is a first generation cephalosporin antibiotic.
The drug is usually administrated either by intramuscular injection (injection into a large muscle) or intravenous infusion (intravenous fluid into a vein).
Category
Cephalosporin, First-Generation
US Brand Names
ANCEF®
FDA Package Insert
Description | Clinical Pharmacology | Microbiology | Indications and Usage | Contraindications | Warnings and Precautions | Adverse Reactions | Clinical Studies | Dosage and Administration | Compatibility, Reconstitution, and Stability | Directions For Use | How Supplied | Labels and Packages
Mechanism of Action
Cefazolin sodium belongs to the first-genaration Cephalosporins.Cephalosporins are bactericidal and have the same mode of action as other beta-lactam antibiotics (such as penicillins). Cephalosporins disrupt the synthesis of the peptidoglycan layer of bacterial cell walls. The peptidoglycan layer is important for cell wall structural integrity, especially in Gram-positive organisms. The final transpeptidation step in the synthesis of the peptidoglycan is facilitated by transpeptidases known as penicillins binding proteins (PBPs)