Azithromycin (ophthalmic): Difference between revisions
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==Overview== | ==Overview== | ||
'''Azithromycin''' (Zithromax, Azithrocin, Zmax, Azin, Zedd, Azocam, Penalox, Azi-Once, Zeto)<ref>{{cite web |url=http://www.nlm.nih.gov/medlineplus/druginfo/meds/a697037.html |title=Azithromycin |author=[[American Society of Health-System Pharmacists]] |work=[[MedlinePlus]] |publisher=[[United States National Library of Medicine]] |date=October 15, 2012 |accessdate=September 19, 2013}}</ref> is an [[azalide]], a subclass of [[macrolide]] [[antibiotics|antibiotics.]] It is derived from [[erythromycin]], with a [[methyl]]-substituted [[nitrogen]] [[atom]] incorporated into the [[lactone]] ring, thus making the lactone ring 15-membered. | '''Azithromycin''' (Zithromax, Azithrocin, Zmax, Azin, Zedd, Azocam, Penalox, Azi-Once, Zeto)<ref>{{cite web |url=http://www.nlm.nih.gov/medlineplus/druginfo/meds/a697037.html |title=Azithromycin |author=[[American Society of Health-System Pharmacists]] |work=[[MedlinePlus]] |publisher=[[United States National Library of Medicine]] |date=October 15, 2012 |accessdate=September 19, 2013}}</ref> is an [[azalide]], a subclass of [[macrolide]] [[antibiotics|antibiotics.]] It is derived from [[erythromycin]], with a [[methyl]]-substituted [[nitrogen]] [[atom]] incorporated into the [[lactone]] ring, thus making the lactone ring 15-membered. | ||
==Category== | ==Category== | ||
Macrolide, Azalide | |||
==US Brand Names== | ==US Brand Names== | ||
ZITHROMAX<sup>®</sup> | ZITHROMAX<sup>®</sup> | ||
==FDA Package Insert== | ==FDA Package Insert== | ||
'''[[Azithromycin description|Description]]''' | |||
''' [[Azithromycin description|Description]]''' | |||
'''| [[Azithromycin clinical pharmacology|Clinical Pharmacology]]''' | '''| [[Azithromycin clinical pharmacology|Clinical Pharmacology]]''' | ||
'''| [[Azithromycin microbiology|Microbiology]]''' | '''| [[Azithromycin microbiology|Microbiology]]''' | ||
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==Mechanism of Action== | ==Mechanism of Action== | ||
Azithromycin prevents [[bacterium|bacteria]] from growing by interfering with their [[protein synthesis]]. It binds to the 50S subunit of the bacterial [[ribosome]], and thus inhibits [[translation (biology)|translation]] of [[mRNA]]. Nucleic acid synthesis is not affected.<ref>{{cite web|url=http://www.medicinenet.com/azithromycin/article.htm |title=azithromycin (Zithromax, Zmax, Z-Pak) - Side Effects, Drug Interactions |publisher=MedicineNet |date= |accessdate=2013-01-06}}</ref> | Azithromycin prevents [[bacterium|bacteria]] from growing by interfering with their [[protein synthesis]]. It binds to the 50S subunit of the bacterial [[ribosome]], and thus inhibits [[translation (biology)|translation]] of [[mRNA]]. Nucleic acid synthesis is not affected.<ref>{{cite web|url=http://www.medicinenet.com/azithromycin/article.htm |title=azithromycin (Zithromax, Zmax, Z-Pak) - Side Effects, Drug Interactions |publisher=MedicineNet |date= |accessdate=2013-01-06}}</ref> | ||
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{{Reflist|2}} | {{Reflist|2}} | ||
[[Category: | [[Category:Antibiotics]] | ||
[[Category:Wikinfect]] | [[Category:Wikinfect]] | ||
Revision as of 19:45, 5 January 2014
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Overview
Azithromycin (Zithromax, Azithrocin, Zmax, Azin, Zedd, Azocam, Penalox, Azi-Once, Zeto)[1] is an azalide, a subclass of macrolide antibiotics. It is derived from erythromycin, with a methyl-substituted nitrogen atom incorporated into the lactone ring, thus making the lactone ring 15-membered.
Category
Macrolide, Azalide
US Brand Names
ZITHROMAX®
FDA Package Insert
Description | Clinical Pharmacology | Microbiology | Indications and Usage | Contraindications | Warnings and Precautions | Adverse Reactions | Clinical Studies | Dosage and Administration | Compatibility, Reconstitution, and Stability | How Supplied | Labels and Packages
Mechanism of Action
Azithromycin prevents bacteria from growing by interfering with their protein synthesis. It binds to the 50S subunit of the bacterial ribosome, and thus inhibits translation of mRNA. Nucleic acid synthesis is not affected.[2]
References
- ↑ American Society of Health-System Pharmacists (October 15, 2012). "Azithromycin". MedlinePlus. United States National Library of Medicine. Retrieved September 19, 2013.
- ↑ "azithromycin (Zithromax, Zmax, Z-Pak) - Side Effects, Drug Interactions". MedicineNet. Retrieved 2013-01-06.