Caspofungin: Difference between revisions

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|offLabelAdultGuideSupport=There is limited information regarding <i>Off-Label Guideline-Supported Use</i> of Caspofungin in adult patients.
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|offLabelPedGuideSupport=There is limited information regarding <i>Off-Label Guideline-Supported Use</i> of Caspofungin in pediatric patients.
|offLabelPedNoGuideSupport=There is limited information regarding <i>Off-Label Non–Guideline-Supported Use</i> of Caspofungin in pediatric patients.
|alcohol=Alcohol-Caspofungin interaction has not been established. Talk to your doctor about the effects of taking alcohol with this medication.
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Revision as of 12:58, 9 December 2014

Caspofungin
Adult Indications & Dosage
Pediatric Indications & Dosage
Contraindications
Warnings & Precautions
Adverse Reactions
Drug Interactions
Use in Specific Populations
Administration & Monitoring
Overdosage
Pharmacology
Clinical Studies
How Supplied
Images
Patient Counseling Information
Precautions with Alcohol
Brand Names
Look-Alike Names

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Kiran Singh, M.D. [2]

Disclaimer

WikiDoc MAKES NO GUARANTEE OF VALIDITY. WikiDoc is not a professional health care provider, nor is it a suitable replacement for a licensed healthcare provider. WikiDoc is intended to be an educational tool, not a tool for any form of healthcare delivery. The educational content on WikiDoc drug pages is based upon the FDA package insert, National Library of Medicine content and practice guidelines / consensus statements. WikiDoc does not promote the administration of any medication or device that is not consistent with its labeling. Please read our full disclaimer here.

Overview

Caspofungin is {{{aOrAn}}} {{{drugClass}}} that is FDA approved for the {{{indicationType}}} of {{{indication}}}. Common adverse reactions include {{{adverseReactions}}}.

Adult Indications and Dosage

FDA-Labeled Indications and Dosage (Adult)

There is limited information regarding Caspofungin FDA-Labeled Indications and Dosage (Adult) in the drug label.

Off-Label Use and Dosage (Adult)

Guideline-Supported Use

There is limited information regarding Off-Label Guideline-Supported Use of Caspofungin in adult patients.

Non–Guideline-Supported Use

There is limited information regarding Off-Label Non–Guideline-Supported Use of Caspofungin in adult patients.

Pediatric Indications and Dosage

FDA-Labeled Indications and Dosage (Pediatric)

There is limited information regarding Caspofungin FDA-Labeled Indications and Dosage (Pediatric) in the drug label.

Off-Label Use and Dosage (Pediatric)

Guideline-Supported Use

There is limited information regarding Off-Label Guideline-Supported Use of Caspofungin in pediatric patients.

Non–Guideline-Supported Use

There is limited information regarding Off-Label Non–Guideline-Supported Use of Caspofungin in pediatric patients.

Contraindications

There is limited information regarding Caspofungin Contraindications in the drug label.

Warnings

There is limited information regarding Caspofungin Warnings' in the drug label.

Adverse Reactions

Clinical Trials Experience

There is limited information regarding Caspofungin Clinical Trials Experience in the drug label.

Postmarketing Experience

There is limited information regarding Caspofungin Postmarketing Experience in the drug label.

Drug Interactions

There is limited information regarding Caspofungin Drug Interactions in the drug label.

Use in Specific Populations

Pregnancy

Pregnancy Category (FDA): There is no FDA guidance on usage of Caspofungin in women who are pregnant.
Pregnancy Category (AUS): There is no Australian Drug Evaluation Committee (ADEC) guidance on usage of Caspofungin in women who are pregnant.

Labor and Delivery

There is no FDA guidance on use of Caspofungin during labor and delivery.

Nursing Mothers

There is no FDA guidance on the use of Caspofungin in women who are nursing.

Pediatric Use

There is no FDA guidance on the use of Caspofungin in pediatric settings.

Geriatic Use

There is no FDA guidance on the use of Caspofungin in geriatric settings.

Gender

There is no FDA guidance on the use of Caspofungin with respect to specific gender populations.

Race

There is no FDA guidance on the use of Caspofungin with respect to specific racial populations.

Renal Impairment

There is no FDA guidance on the use of Caspofungin in patients with renal impairment.

Hepatic Impairment

There is no FDA guidance on the use of Caspofungin in patients with hepatic impairment.

Females of Reproductive Potential and Males

There is no FDA guidance on the use of Caspofungin in women of reproductive potentials and males.

Immunocompromised Patients

There is no FDA guidance one the use of Caspofungin in patients who are immunocompromised.

Administration and Monitoring

Administration

There is limited information regarding Caspofungin Administration in the drug label.

Monitoring

There is limited information regarding Caspofungin Monitoring in the drug label.

IV Compatibility

There is limited information regarding the compatibility of Caspofungin and IV administrations.

Overdosage

There is limited information regarding Caspofungin overdosage. If you suspect drug poisoning or overdose, please contact the National Poison Help hotline (1-800-222-1222) immediately.

Pharmacology

There is limited information regarding Caspofungin Pharmacology in the drug label.

Mechanism of Action

There is limited information regarding Caspofungin Mechanism of Action in the drug label.

Structure

There is limited information regarding Caspofungin Structure in the drug label.

Pharmacodynamics

There is limited information regarding Caspofungin Pharmacodynamics in the drug label.

Pharmacokinetics

There is limited information regarding Caspofungin Pharmacokinetics in the drug label.

Nonclinical Toxicology

There is limited information regarding Caspofungin Nonclinical Toxicology in the drug label.

Clinical Studies

There is limited information regarding Caspofungin Clinical Studies in the drug label.

How Supplied

There is limited information regarding Caspofungin How Supplied in the drug label.

Storage

There is limited information regarding Caspofungin Storage in the drug label.

Images

Drug Images

{{#ask: Page Name::Caspofungin |?Pill Name |?Drug Name |?Pill Ingred |?Pill Imprint |?Pill Dosage |?Pill Color |?Pill Shape |?Pill Size (mm) |?Pill Scoring |?NDC |?Drug Author |format=template |template=DrugPageImages |mainlabel=- |sort=Pill Name }}

Package and Label Display Panel

{{#ask: Label Page::Caspofungin |?Label Name |format=template |template=DrugLabelImages |mainlabel=- |sort=Label Page }}

Patient Counseling Information

There is limited information regarding Caspofungin Patient Counseling Information in the drug label.

Precautions with Alcohol

Alcohol-Caspofungin interaction has not been established. Talk to your doctor about the effects of taking alcohol with this medication.

Brand Names

There is limited information regarding Caspofungin Brand Names in the drug label.

Look-Alike Drug Names

There is limited information regarding Caspofungin Look-Alike Drug Names in the drug label.

Drug Shortage Status

Price

References

The contents of this FDA label are provided by the National Library of Medicine.


Caspofungin
CANCIDAS® FDA Package Insert
Description
Clinical Pharmacology
Microbiology
Indications and Usage
Contraindications
Warnings and Precautions
Adverse Reactions
Drug Interactions
Overdosage
Clinical Studies
Dosage and Administration
How Supplied
Labels and Packages

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [3]; Associate Editor(s)-in-Chief: Ahmed Zaghw, M.D. [4]

Overview

Caspofungin (INN[1]) (brand name Cancidas worldwide) is a lipopeptide antifungal drug from Merck & Co., Inc.. It is a member of a new class of antifungals termed the echinocandins. It works by inhibiting the enzyme (1→3)-β-D-glucan synthase and thereby disturbing the integrity of the fungal cell wall. Caspofungin was the first inhibitor of fungal (1→3)-β-D-glucan synthesis to be approved by the United States Food and Drug Administration.[2] Caspofungin is administered intravenously.

Category

Antifungal

US Brand Names

CANCIDAS®

FDA Package Insert

Description | Clinical Pharmacology | Microbiology | Indications and Usage | Contraindications | Warnings and Precautions | Adverse Reactions | Drug Interactions | Overdosage | Clinical Studies | Dosage and Administration | How Supplied | Labels and Packages

Mechanism of Action

References

  1. European Medicines Agency's list of authorised medicines for human use (C)
  2. Deresinski SC; Stevens DA (2003). "Caspofungin". Clin Infect Dis. 36 (11): 1445&ndash, 1457. doi:10.1086/375080. PMID 12766841. Unknown parameter |author-separator= ignored (help)