Diethylcarbamazine description: Difference between revisions
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==Description== | |||
A filaricidal piperazine derivative that kills both the microfilariae and some adult worms of Wuchereria bancrofti, Brugia malayi and B. timori. | |||
It is almost completely absorbed after oral administration and is widely distributed in non-fatty tissues. It is rapidly and extensively metabolized and the residuum is recovered unchanged in the urine within 48 hours. The plasma half-life is usually within the range of 6-12 hours.<ref>{{Cite web | last = | first = | title = WHO Model Prescribing Information: Drugs Used in Parasitic Diseases - Second Edition: Helminths: Lymphatic filariasis: Diethylcarbamazine | url = http://apps.who.int/medicinedocs/en/d/Jh2922e/3.5.1.html#Jh2922e.3.5.1 | publisher = | date = | accessdate = }}</ref> | |||
<ref>{{Cite web | last = | first = | title = WHO Model Prescribing Information: Drugs Used in Parasitic Diseases - Second Edition: Helminths: Lymphatic filariasis: Diethylcarbamazine | url = http://apps.who.int/medicinedocs/en/d/Jh2922e/3.5.1.html#Jh2922e.3.5.1 | publisher = | date = | accessdate = }}</ref> | |||
==References== | ==References== | ||
Latest revision as of 02:09, 7 January 2014
| Diethylcarbamazine |
|---|
| HETRAZAN® WHO Prescribing Information |
| Description |
| Indications and Usage |
| Contraindications |
| Warnings and Precautions |
| Adverse Reactions |
| Overdosage |
| Dosage and Administration |
| How Supplied |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Description
A filaricidal piperazine derivative that kills both the microfilariae and some adult worms of Wuchereria bancrofti, Brugia malayi and B. timori.
It is almost completely absorbed after oral administration and is widely distributed in non-fatty tissues. It is rapidly and extensively metabolized and the residuum is recovered unchanged in the urine within 48 hours. The plasma half-life is usually within the range of 6-12 hours.[1]
References
Adapted from the FDA Package Insert.