Polymyxin B sulfate: Difference between revisions

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'''Neosporin''' is an antibiotic product marketed for the prevention of [[infection]]s and speeding the healing of [[wound]]s.
'''Neosporin''' is an antibiotic product marketed for the prevention of [[infection]]s and speeding the healing of [[wound]]s.
The original ointment contains three different antibiotics: [[bacitracin]], [[neomycin]], and [[polymyxin B]], in a relatively low molecular weight patented base of cocoa butter, cottonseed oil, sodium pyruvate, tocopheryl acetate, and [[petroleum jelly]].
The original ointment contains three different antibiotics: [[bacitracin]], [[neomycin]], and [[polymyxin B]], in a relatively low molecular weight patented base of cocoa butter, cottonseed oil, sodium pyruvate, tocopheryl acetate, and [[petroleum jelly]].
The generic name for these products, regardless of the base, is "Triple Antibiotic Ointment".
In China, this product is called "Complex Polymyxin B Ointment," which is manufactured by Zhejiang Reachall Pharmaceutical. The product was also marketed by The [[Upjohn]] Company under the name "Mycitracin", until 1997 when that name was acquired by Johnson & Johnson.<ref>{{Cite news
|publication-date=1997 June 5
|title=McNeil Consumer Products Co. strengthens worldwide lead in OTC pain reliever market
|format=Press Release
| periodical=Business Wire
|publisher=Business Wire
| publication-place=Fort Washington, PA
|url=http://www.thefreelibrary.com/-a019478196
|accessdate=June 28, 2011
|postscript=}}</ref>


==Category==
==Category==

Revision as of 03:40, 7 January 2014

Polymyxin B sulfate
NEOSPORIN® FDA Package Insert
Description
Clinical Pharmacology
Microbiology
Indications and Usage
Contraindications
Warnings and Precautions
Adverse Reactions
Dosage and Administration
How Supplied
Labels and Packages

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Mohamed Moubarak, M.D. [2]

Overview

Neosporin is an antibiotic product marketed for the prevention of infections and speeding the healing of wounds. The original ointment contains three different antibiotics: bacitracin, neomycin, and polymyxin B, in a relatively low molecular weight patented base of cocoa butter, cottonseed oil, sodium pyruvate, tocopheryl acetate, and petroleum jelly.

Category

Polymyxin antibiotic

US Brand Names

NEOSPORIN®

FDA Package Insert

Description | Clinical Pharmacology | Microbiology | Indications and Usage | Contraindications | Warnings and Precautions | Adverse Reactions | Dosage and Administration | How Supplied

Mechanism of Action

Polymyxin antibiotic is a surface active agent which penetrates into and disrupts the bacterial cell membrane. It has been shown to have bactericidal activity against most strains of the microorganisms.[1]

References

  1. "NEOSPORIN (NEOMYCIN AND POLYMYXIN B SULFATES AND GRAMICIDIN) SOLUTION [MONARCH PHARMACEUTICALS, INC.]". Text " accessdate" ignored (help)