Fluconazole (oral): Difference between revisions

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__NOTOC__
{{DrugProjectFormSinglePage
{{Fluconazole}}
|authorTag=
'''''For patient information, click <u>[[Fluconazole (patient information)|here]]'''''</u>.


{{CMG}}; {{AE}} {{AZ}}


==Overview==
<!--Overview-->
'''Fluconazole''' is a [[triazole]] [[antifungal drug]] used in the treatment and prevention of superficial and systemic fungal infections. In a bulk powder form, it appears as a white crystalline powder, and it is very slightly soluble in water and soluble in alcohol.<ref>[http://www.mpbio.com/product_info.php?products_id=198986 MP Biomedicals]</ref> It is commonly marketed under the trade names Diflucan and Trican ([[Pfizer]]).
==Category==
Antifungal
==US Brand Names==
DIFLUCAN<sup>®</sup>
==FDA Package Insert==


'''  [[Fluconazole description|Description]]'''
|genericName=
'''| [[Fluconazole clinical pharmacology|Clinical Pharmacology]]'''
'''| [[Fluconazole microbiology|Microbiology]]'''
'''| [[Fluconazole indications and usage|Indications and Usage]]'''
'''| [[Fluconazole contraindications|Contraindications]]'''
'''| [[Fluconazole warnings and precautions|Warnings and Precautions]]'''
'''| [[Fluconazole adverse reactions|Adverse Reactions]]'''
'''| [[Fluconazole drug interactions|Drug Interactions]]'''
'''| [[Fluconazole overdosage|Overdosage]]'''
'''| [[Fluconazole clinical studies|Clinical Studies]]'''
'''| [[Fluconazole dosage and administration|Dosage and Administration]]'''
'''| [[Fluconazole how supplied|How Supplied]]'''
'''| [[Fluconazole labels and packages|Labels and Packages]]'''


==Mechanism of Action==
Azole group antifungal drug.
==References==
{{Reflist|2}}


[[Category:Antibiotics]]
 
[[Category:Wikinfect]]
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a
 
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Yes
 
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|fdaLIADAdult=
 
=====Condition1=====
 
* Dosing Information
 
:* Dosage
 
=====Condition2=====
 
* Dosing Information
 
:* Dosage
 
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* Dosing Information
 
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* Dosing Information
 
:* Dosage
 
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=====Condition1=====
 
* Developed by:
 
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|warnings=
 
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=====Body as a Whole=====
 
 
 
=====Cardiovascular=====
 
 
 
=====Digestive=====
 
 
 
=====Endocrine=====
 
 
 
=====Hematologic and Lymphatic=====
 
 
 
=====Metabolic and Nutritional=====
 
 
 
=====Musculoskeletal=====
 
 
 
=====Neurologic=====
 
 
 
=====Respiratory=====
 
 
 
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|useInRace=
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|useInRenalImpair=
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|useInHepaticImpair=
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|useInImmunocomp=
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<!--Administration and Monitoring-->
 
|administration=
 
* Oral
 
* Intravenous
 
|monitoring=
 
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===Acute Overdose===
 
====Signs and Symptoms====
 
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[[Category:Drug]]

Revision as of 17:41, 16 October 2014

Fluconazole (oral)
Black Box Warning
Adult Indications & Dosage
Pediatric Indications & Dosage
Contraindications
Warnings & Precautions
Adverse Reactions
Drug Interactions
Use in Specific Populations
Administration & Monitoring
Overdosage
Pharmacology
Clinical Studies
How Supplied
Images
Patient Counseling Information
Precautions with Alcohol
Brand Names
Look-Alike Names

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1];

Disclaimer

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Black Box Warning

Title
See full prescribing information for complete Boxed Warning.
ConditionName:
  • Content

Overview

Fluconazole (oral) is a that is FDA approved for the {{{indicationType}}} of . There is a Black Box Warning for this drug as shown here. Common adverse reactions include .

Adult Indications and Dosage

FDA-Labeled Indications and Dosage (Adult)

Condition1
  • Dosing Information
  • Dosage
Condition2
  • Dosing Information
  • Dosage
Condition3
  • Dosing Information
  • Dosage
Condition4
  • Dosing Information
  • Dosage

Off-Label Use and Dosage (Adult)

Guideline-Supported Use

Condition1
  • Developed by:
  • Class of Recommendation:
  • Strength of Evidence:
  • Dosing Information
  • Dosage
Condition2

There is limited information regarding Off-Label Guideline-Supported Use of Fluconazole (oral) in adult patients.

Non–Guideline-Supported Use

Condition1
  • Dosing Information
  • Dosage
Condition2

There is limited information regarding Off-Label Non–Guideline-Supported Use of Fluconazole (oral) in adult patients.

Pediatric Indications and Dosage

FDA-Labeled Indications and Dosage (Pediatric)

Condition1
  • Dosing Information
  • Dosage
Condition2

There is limited information regarding FDA-Labeled Use of Fluconazole (oral) in pediatric patients.

Off-Label Use and Dosage (Pediatric)

Guideline-Supported Use

Condition1
  • Developed by:
  • Class of Recommendation:
  • Strength of Evidence:
  • Dosing Information
  • Dosage
Condition2

There is limited information regarding Off-Label Guideline-Supported Use of Fluconazole (oral) in pediatric patients.

Non–Guideline-Supported Use

Condition1
  • Dosing Information
  • Dosage
Condition2

There is limited information regarding Off-Label Non–Guideline-Supported Use of Fluconazole (oral) in pediatric patients.

Contraindications

  • Condition1

Warnings

Title
See full prescribing information for complete Boxed Warning.
ConditionName:
  • Content
  • Description

Precautions

  • Description

Adverse Reactions

Clinical Trials Experience

There is limited information regarding Clinical Trial Experience of Fluconazole (oral) in the drug label.

Body as a Whole
Cardiovascular
Digestive
Endocrine
Hematologic and Lymphatic
Metabolic and Nutritional
Musculoskeletal
Neurologic
Respiratory
Skin and Hypersensitivy Reactions
Special Senses
Urogenital
Miscellaneous

Postmarketing Experience

There is limited information regarding Postmarketing Experience of Fluconazole (oral) in the drug label.

Body as a Whole
Cardiovascular
Digestive
Endocrine
Hematologic and Lymphatic
Metabolic and Nutritional
Musculoskeletal
Neurologic
Respiratory
Skin and Hypersensitivy Reactions
Special Senses
Urogenital
Miscellaneous

Drug Interactions

  • Drug
  • Description

Use in Specific Populations

Pregnancy

Pregnancy Category (FDA):

  • Pregnancy Category


Pregnancy Category (AUS):

  • Australian Drug Evaluation Committee (ADEC) Pregnancy Category

There is no Australian Drug Evaluation Committee (ADEC) guidance on usage of Fluconazole (oral) in women who are pregnant.

Labor and Delivery

There is no FDA guidance on use of Fluconazole (oral) during labor and delivery.

Nursing Mothers

There is no FDA guidance on the use of Fluconazole (oral) with respect to nursing mothers.

Pediatric Use

There is no FDA guidance on the use of Fluconazole (oral) with respect to pediatric patients.

Geriatic Use

There is no FDA guidance on the use of Fluconazole (oral) with respect to geriatric patients.

Gender

There is no FDA guidance on the use of Fluconazole (oral) with respect to specific gender populations.

Race

There is no FDA guidance on the use of Fluconazole (oral) with respect to specific racial populations.

Renal Impairment

There is no FDA guidance on the use of Fluconazole (oral) in patients with renal impairment.

Hepatic Impairment

There is no FDA guidance on the use of Fluconazole (oral) in patients with hepatic impairment.

Females of Reproductive Potential and Males

There is no FDA guidance on the use of Fluconazole (oral) in women of reproductive potentials and males.

Immunocompromised Patients

There is no FDA guidance one the use of Fluconazole (oral) in patients who are immunocompromised.

Administration and Monitoring

Administration

  • Oral
  • Intravenous

Monitoring

There is limited information regarding Monitoring of Fluconazole (oral) in the drug label.

  • Description

IV Compatibility

There is limited information regarding IV Compatibility of Fluconazole (oral) in the drug label.

Overdosage

Acute Overdose

Signs and Symptoms

  • Description

Management

  • Description

Chronic Overdose

There is limited information regarding Chronic Overdose of Fluconazole (oral) in the drug label.

Pharmacology

There is limited information regarding Fluconazole (oral) Pharmacology in the drug label.

Mechanism of Action

Structure

File:Fluconazole (oral)01.png
This image is provided by the National Library of Medicine.

Pharmacodynamics

There is limited information regarding Pharmacodynamics of Fluconazole (oral) in the drug label.

Pharmacokinetics

There is limited information regarding Pharmacokinetics of Fluconazole (oral) in the drug label.

Nonclinical Toxicology

There is limited information regarding Nonclinical Toxicology of Fluconazole (oral) in the drug label.

Clinical Studies

There is limited information regarding Clinical Studies of Fluconazole (oral) in the drug label.

How Supplied

Storage

There is limited information regarding Fluconazole (oral) Storage in the drug label.

Images

Drug Images

{{#ask: Page Name::Fluconazole (oral) |?Pill Name |?Drug Name |?Pill Ingred |?Pill Imprint |?Pill Dosage |?Pill Color |?Pill Shape |?Pill Size (mm) |?Pill Scoring |?NDC |?Drug Author |format=template |template=DrugPageImages |mainlabel=- |sort=Pill Name }}

Package and Label Display Panel

{{#ask: Label Page::Fluconazole (oral) |?Label Name |format=template |template=DrugLabelImages |mainlabel=- |sort=Label Page }}

Patient Counseling Information

There is limited information regarding Patient Counseling Information of Fluconazole (oral) in the drug label.

Precautions with Alcohol

  • Alcohol-Fluconazole (oral) interaction has not been established. Talk to your doctor about the effects of taking alcohol with this medication.

Brand Names

Look-Alike Drug Names

Drug Shortage Status

Price

References

The contents of this FDA label are provided by the National Library of Medicine.

  1. ↑ Empty citation (help)
  2. ↑ "http://www.ismp.org". External link in |title= (help)


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