Clarithromycin description: Difference between revisions

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==Description==
__NOTOC__
{{Clarithromycin}}
{{CMG}}; {{AE}} {{chetan}}


Clarithromycin is a semi-synthetic macrolide antibiotic. Chemically, it is 6-0-methylerythromycin. The molecular formula is C38H69NO13, and the molecular weight is 747.96. The structural formula is:


Clarithromycin is a white to off-white crystalline powder. It is soluble in [[acetone]], slightly soluble in [[methanol]], ethanol, and acetonitrile, and practically insoluble in water.


BIAXIN is available as immediate-release tablets, extended-release tablets, and granules for oral suspension.
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Each yellow oval film-coated immediate-release BIAXIN tablet (clarithromycin tablets, USP) contains 250 mg or 500 mg of clarithromycin and the following inactive ingredients:
==References==
{{Reflist}}


250 mg tablets: hypromellose, hydroxypropyl cellulose, croscarmellose sodium, D&C Yellow No. 10, FD&C Blue No. 1, magnesium stearate, microcrystalline cellulose, povidone, pregelatinized starch, propylene glycol, silicon dioxide, sorbic acid, sorbitan monooleate, stearic acid, talc, titanium dioxide, and vanillin.
{{FDA}}
 
500 mg tablets: hypromellose, hydroxypropyl cellulose, colloidal silicon dioxide, croscarmellose sodium, D&C Yellow No. 10, magnesium stearate, microcrystalline cellulose, povidone, propylene glycol, sorbic acid, sorbitan monooleate, titanium dioxide, and vanillin.
 
Each yellow oval film-coated BIAXIN XL tablet (clarithromycin extended-release tablets) contains 500 mg of clarithromycin and the following inactive ingredients: cellulosic polymers, D&C Yellow No. 10, lactose monohydrate, magnesium stearate, propylene glycol, sorbic acid, sorbitan monooleate, talc, titanium dioxide, and vanillin.
 
After constitution, each 5 mL of BIAXIN suspension (clarithromycin for oral suspension, USP) contains 125 mg or 250 mg of clarithromycin. Each bottle of BIAXIN granules contains 1250 mg (50 mL size), 2500 mg (50 and 100 mL sizes) or 5000 mg (100 mL size) of clarithromycin and the following inactive ingredients: carbomer, castor oil, citric acid, hypromellose phthalate, maltodextrin, potassium sorbate, povidone, silicon dioxide, sucrose, xanthan gum, titanium dioxide and fruit punch flavor.
 
 
 
 
 
 
 
 
<ref name="dailymed.nlm.nih.gov">{{Cite web  | last =  | first =  | title = BIAXIN (CLARITHROMYCIN) TABLET, FILM COATED BIAXIN (CLARITHROMYCIN) TABLET, FILM COATED, EXTENDED RELEASE BIAXIN (CLARITHROMYCIN) GRANULE, FOR SUSPENSION [ABBVIE INC.] | url = http://dailymed.nlm.nih.gov/dailymed/lookup.cfm?setid=aa44552c-3cfe-4111-8aa5-4251aeed9be9 | publisher =  | date =  | accessdate = }}</ref>


[[Category:Antibiotics]]
[[Category:Wikinfect]]


==References==
==References==

Revision as of 21:47, 8 January 2014

Clarithromycin
BIAXIN® FDA Package Insert
Description
Clinical Pharmacology
Microbiology
Indications and Usage
Contraindications
Warnings and Precautions
Adverse Reactions
Drug Interactions
Overdosage
Dosage and Administration
How Supplied
Labels and Packages

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Chetan Lokhande, M.B.B.S [2]


Clarithromycin
BIAXIN® FDA Package Insert
Description
Clinical Pharmacology
Microbiology
Indications and Usage
Contraindications
Warnings and Precautions
Adverse Reactions
Drug Interactions
Overdosage
Dosage and Administration
How Supplied
Labels and Packages

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [3]; Associate Editor(s)-in-Chief: Chetan Lokhande, M.B.B.S [4]


[1]

References

  1. "BIAXIN (CLARITHROMYCIN) TABLET, FILM COATED BIAXIN (CLARITHROMYCIN) TABLET, FILM COATED, EXTENDED RELEASE BIAXIN (CLARITHROMYCIN) GRANULE, FOR SUSPENSION [ABBVIE INC.]".

Adapted from the FDA Package Insert.

References

Adapted from the FDA Package Insert.