Ofloxacin (oral): Difference between revisions

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{{drugbox
__NOTOC__
| IUPAC_name = (+/-)-9-fluoro-2, 3-dihydro-3-methyl-10-(4-methyl-1-piperazinyl)- 7-oxo-7''H''-pyrido [1,2,3-de]-1, 4-benzoxazine-6-carboxylic acid
{{Ofloxacin}}
| image = Ofloxacin.svg
'''''For patient information, click <u>[[Ofloxacin (patient information)|here]]</u>'''''.
| CAS_number = 82419-36-1
| ATC_prefix = J01
| ATC_suffix = MA01
| ATC_supplemental = {{ATC|J01|MA02}}, {{ATC|J01|MA12}}, {{ATC|S01|AX11}}, {{ATC|S01|AX13}}, {{ATC|S01|AX19}}, {{ATC|S03|AA07}}
| PubChem = 4583
| DrugBank = APRD00502
| C = 18 | H = 20 | F = 1 | N = 3 | O = 4
| molecular_weight = 361.368 g/mol
| bioavailability =
| protein_bound = 32%
| metabolism =
| elimination_half-life = 9 hours
| pregnancy_US = C
| legal_US = Rx-only
| routes_of_administration = [[Topical]] ([[ear drop]]s)
}}
{{SI}}


{{CMG}}


'''Ofloxacin''' (sold under the brand name '''Floxin&reg;''' in the [[United States]], '''Tarivid®''' in Europe and some other countries) is a [[fluoroquinolone]] [[antibiotic]]. Ofloxacin is the [[racemate|racemic]] mixture of the [[Chirality (chemistry)|chiral]] compound. The biologically active [[enantiomer]] is sold separately under the name of [[levofloxacin]].  It is used as a treatment for [[Gonorrhoea#Treatment|gonorrhoea]] and is an alternative treatment to [[ciprofloxacin]] for [[anthrax]].
==Overview==
'''Ofloxacin''' (sold under the brand name '''Floxin&reg;''' in the [[United States]], '''Tarivid®''' in Europe and some other countries) is a[[fluoroquinolone]] [[antibiotic]]. Ofloxacin is the [[racemate|racemic]] mixture of the [[Chirality (chemistry)|chiral]] compound. The biologically active [[enantiomer]] is sold separately under the name of [[levofloxacin]].  It is used as a treatment for [[Gonorrhoea#Treatment|gonorrhoea]] and is an alternative treatment to [[ciprofloxacin]] for [[anthrax]].
==Category==
Fluoroquinolone
==US Brand Names==
Ocuflox<sup>®</sup>
==FDA Package Insert==


==External links==
'''  [[Ofloxacin description|Description]]'''
* [http://www.cbwinfo.com/Pharmaceuticals/Ofloxacin.html Ofloxacin: an overview] - A site with its chemical properties and alternate brand names.
'''| [[Ofloxacin clinical pharmacology|Clinical Pharmacology]]'''
'''| [[Ofloxacin microbiology|Microbiology]]'''
'''| [[Ofloxacin indications and usage|Indications and Usage]]'''
'''| [[Ofloxacin contraindications|Contraindications]]'''
'''| [[Ofloxacin warnings and precautions|Warnings and Precautions]]'''
'''| [[Ofloxacin adverse reactions|Adverse Reactions]]'''
'''| [[Ofloxacin drug interactions|Drug Interactions]]'''
'''| [[Ofloxacin overdosage|Overdosage]]'''
'''| [[Ofloxacin clinical studies|Clinical Studies]]'''
'''| [[Ofloxacin dosage and administration|Dosage and Administration]]'''
'''| [[Ofloxacin how supplied|How Supplied]]'''
'''| [[Ofloxacin labels and packages|Labels and Packages]]'''


{{QuinoloneAntiBiotics}}
==Mechanism of Action==


==References==
{{Reflist|2}}


[[Category:Fluoroquinolone antibiotics]]
[[Category:Antibiotics]]
 
[[Category:Wikinfect]]
 
[[de:Ofloxacin]]
[[fr:Ofloxacine]]
[[nl:Ofloxacine]]
[[pl:Ofloksacyna]]
[[pt:Ofloxacina]]
[[th:ออฟลอกซาซิน]]
[[zh:氧氟沙星]]
 
{{WH}}
{{WikiDoc Sources}}

Revision as of 22:05, 8 January 2014

Ofloxacin
OCUFLOX ® FDA Package Insert
Description
Clinical Pharmacology
Microbiology
Indications and Usage
Contraindications
Warnings and Precautions
Adverse Reactions
Drug Interactions
Dosage and Administration
How Supplied
Labels and Packages

For patient information, click here.

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Overview

Ofloxacin (sold under the brand name Floxin® in the United States, Tarivid® in Europe and some other countries) is afluoroquinolone antibiotic. Ofloxacin is the racemic mixture of the chiral compound. The biologically active enantiomer is sold separately under the name of levofloxacin. It is used as a treatment for gonorrhoea and is an alternative treatment to ciprofloxacin for anthrax.

Category

Fluoroquinolone

US Brand Names

Ocuflox®

FDA Package Insert

Description | Clinical Pharmacology | Microbiology | Indications and Usage | Contraindications | Warnings and Precautions | Adverse Reactions | Drug Interactions | Overdosage | Clinical Studies | Dosage and Administration | How Supplied | Labels and Packages

Mechanism of Action

References

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