Levofloxacin (oral): Difference between revisions

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<small>'''''Synonyms / Brand Names: L-Ofloxacin, levofloxacin, Cravit, Cravit Ophthalmic, Elequine, Floxel, Iquix, Leroxacin, Lesacin, Levaquin, Levokacin, Levox, Levoxacin, Mosardal, Nofaxin, Quixin, Reskuin, Tavanic, Volequin
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''''' </small>
{{Levofloxacin}}
{{CMG}};{{AE}}{{AK}}


{{CMG}}
'''''For patient information, click <u>[[Levofloxacin(patient information)|here]]'''''</u>.


==Dosing and Administration==
==Overview==
'''Acute Bacterial Exacerbation of Chronic Bronchitis (Adults)'''<br>
'''Levofloxacin''' (trade names '''Levaquin''' (US), '''Tavanic''' (EU), and others) is a broad spectrum  [[antibiotic]] of the [[fluoroquinolone]] drug class,
PO / IV 500 mg every 24 h for 7 days.
and the levo isomer of its predecessor [[ofloxacin]]. Its spectrum of activity includes most strains of bacterial pathogens responsible for respiratory, urinary tract, gastrointestinal, and abdominal infections.
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'''Acute Bacterial Sinusitis'''(Adults)<br>
PO / IV 500 mg every 24 h for 10 to 14 days or 750 mg every 24 h for 5 days.
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'''Anthrax (inhalational; postexposure)(Adults)'''<br>
PO / IV 500 mg every 24 h for 60 days.
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'''Chronic Bacterial Prostatitis(Adults)'''<br>
PO / IV 500 mg every 24 h for 28 days.
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'''Community-Acquired Pneumonia(Adults)'''<br>
PO / IV 500 mg every 24 h for 7 to 14 days, or 750 mg every 24 h for 5 days.
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<font size="4">
[[{{PAGENAME}}#FDA Package Insert Resources|FDA Package Insert Resources]]
<br></font size><small>Indications, Contraindications, Side Effects, Drug Interactions, etc.</small><font size="4"><br>
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[http://www.pace-med-apps.com/gfrcalc.htm Calculate Creatine Clearance]
<br></font size><small>On line calculator of your patients Cr Cl by a variety of formulas.</small><font size="4"><br>
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[http://home.earthlink.net/~sensei11/convert.htm Convert pounds to Kilograms]
<br></font size><small>On line calculator of your patients weight in pounds to Kg for dosing estimates.</small><font size="4"><br>
<br> [[{{PAGENAME}}#Publication Resources|Publication Resources]]
<br></font size><small>Recent articles, WikiDoc State of the Art Review, Textbook Information</small><font size="4"><br>
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[[{{PAGENAME}}#Trial Resources|Trial Resources]]
<br></font size><small>Ongoing Trials, Trial Results</small><font size="4"><br>
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[[{{PAGENAME}}#Guidelines & Evidence Based Medicine Resources|Guidelines & Evidence Based Medicine Resources]]
<br></font size><small>US National Guidelines, Cochrane Collaboration, etc.</small><font size="4"><br>
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[[{{PAGENAME}}#Media Resources|Media Resources]]
<br></font size><small>Slides, Video, Images, MP3, Podcasts, etc.</small><font size="4"><br><br>
[[{{PAGENAME}}#Patient Resources|Patient Resources]]
<br></font size><small>Discussion Groups, Handouts, Blogs, News, etc.</small><font size="4"><br>
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[[{{PAGENAME}}#International Resources|International Resources]]
<br></font size><small>en Español</small><font size="4"><br>
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==FDA Package Insert Resources==
[[{{PAGENAME}} indications|Indications]]
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[[{{PAGENAME}} contraindications|Contraindications]]
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[[{{PAGENAME}} side effects|Side Effects]]
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[[{{PAGENAME}} drug interactions|Drug Interactions]]
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[[{{PAGENAME}} precautions|Precautions]]
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[[{{PAGENAME}} overdose|Overdose]]
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[[{{PAGENAME}} instructions for administration|Instructions for Administration]]
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[[{{PAGENAME}} how supplied|How Supplied]]
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[[{{PAGENAME}} pharmacokinetics and molecular data|Pharmacokinetics and Molecular Data]]
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[http://www.fda.gov/cder/foi/label/2008/020634s051,020635s055,021721s019lbl.pdf FDA label]
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[http://google2.fda.gov/search?q={{urlencode:{{#if:{{{1|}}}|{{{1}}}|{{PAGENAME}}}}}}&x=0&y=0&client=FDA&site=FDA&lr=&proxystylesheet=FDA&output=xml_no_dtd&getfields=* FDA on {{PAGENAME}}]
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</font size><small>[[{{PAGENAME}}#Dosing and Administration|Return to top]]</small><font size="4">
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==Publication Resources==
==Category==
[http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?CMD=search&db=pubmed&term={{urlencode:{{#if:{{{1|}}}|{{{1}}}|{{PAGENAME}}}}}} Most Recent Articles on {{#if:{{{1|}}}|{{{1}}}|{{PAGENAME}}}}]
[[Fluoroquinolone]], third generation.
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[http://www.ncbi.nlm.nih.gov/sites/entrez?cmd=search&db=pubmed&term={{urlencode:{{#if:{{{1|}}}|{{{1}}}|{{PAGENAME}}}}}}%20AND%20systematic%5Bsb%5D  Review Articles on {{PAGENAME}}]
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[http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&db=pubmed&term={{urlencode:{{#if:{{{1|}}}|{{{1}}}|{{PAGENAME}}}}}}+AND+%28%28N+Engl+J+Med%5Bta%5D%29+OR+%28Lancet%5Bta%5D%29+OR+%28BMJ%5Bta%5D%29%29 Articles on {{PAGENAME}} in N Eng J Med, Lancet, BMJ]
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[[WikiDoc state of the art review on {{PAGENAME}}|WikiDoc State of the Art Review]]
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[http://books.google.com/books?ie=UTF-8&oe=utf-8&q={{urlencode:{{#if:{{{1|}}}|{{{1}}}|{{PAGENAME}}}}}}&qt_s=Search&sa=N&tab=gp Textbook Information on {{PAGENAME}}]
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</font size><small>[[{{PAGENAME}}#Dosing and Administration|Return to top]]</small><font size="4">
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==Trial Resources==
==US Brand Names==
[http://clinicaltrials.gov/search/open/condition={{urlencode:{{#if:{{{1|}}}|{{{1}}}|{{PAGENAME}}}}}} Ongoing Trials with {{PAGENAME}} at Clinical Trials.gov]
LEVAQUIN®, LEVOFLOXACIN®.
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[http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&db=pubmed&term={{urlencode:{{#if:{{{1|}}}|{{{1}}}|{{PAGENAME}}}}}}+AND+%28randomized+controlled+trial%5BPublication+Type%5D+OR+%28randomized%5BTitle%2FAbstract%5D+AND+controlled%5BTitle%2FAbstract%5D+AND+trial%5BTitle%2FAbstract%5D%29%29 Trial Results with {{PAGENAME}}]
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</font size><small>[[{{PAGENAME}}#Dosing and Administration|Return to top]]</small><font size="4">
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==Guidelines & Evidence Based Medicine Resources==
[http://www.guideline.gov/search/searchresults.aspx?Type=3&txtSearch={{urlencode:{{#if:{{{1|}}}|{{{1}}}|{{PAGENAME}}}}}}&num=20 US National Guidelines Clearinghouse on {{PAGENAME}}]
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[http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&db=pubmed&term={{urlencode:({{#if:{{{1|}}}|{{{1}}}|{{PAGENAME}}}}) AND (Cochrane Database Syst Rev[ta])}} Cochrane Collaboration on {{PAGENAME}}]
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[http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&db=pubmed&term={{urlencode:({{#if:{{{1|}}}|{{{1}}}|{{PAGENAME}}}}) AND (Cost effectiveness)}} Cost Effectiveness of {{PAGENAME}}]
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</font size><small>[[{{PAGENAME}}#Dosing and Administration|Return to top]]</small><font size="4">
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==Media Resources==
[http://www.google.com/search?q={{urlencode:{{#if:{{{1|}}}|{{{1}}}|{{PAGENAME}}}}}}+ppt&ie=utf-8&oe=utf-8&aq=t&rls=org.mozilla:en-US:official&client=firefox-a Powerpoint Slides on {{PAGENAME}}]
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[http://images.google.com/images?q={{urlencode:{{#if:{{{1|}}}|{{{1}}}|{{PAGENAME}}}}}}&ie=UTF-8&oe=utf-8&rls=org.mozilla:en-US:official&client=firefox-a&um=1&sa=N&tab=wi Images of {{PAGENAME}}]
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[http://www.google.com/search?hl=en&client=firefox-a&rls=org.mozilla%3Aen-US%3Aofficial&hs=hPo&q={{urlencode:{{#if:{{{1|}}}|{{{1}}}|{{PAGENAME}}}}}}+podcasts+OR+MP3&btnG=Search Podcasts & MP3s on {{PAGENAME}}]
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[http://video.google.com/videosearch?q={{urlencode:{{#if:{{{1|}}}|{{{1}}}|{{PAGENAME}}}}}}&ie=UTF-8&oe=utf-8&rls=org.mozilla:en-US:official&um=1&sa=N&tab=fv# Videos on {{PAGENAME}}]
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</font size><small>[[{{PAGENAME}}#Dosing and Administration|Return to top]]</small><font size="4">
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==Patient Resources==
[[{{PAGENAME}} (patient information)|Patient Information from National Library of Medicine]]
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[http://www.google.com/search?hl=en&q={{urlencode:{{#if:{{{1|}}}|{{{1}}}|{{PAGENAME}}}}}}+more:for_patients&cx=disease_for_patients&sa=N&oi=cooptsr&resnum=0&ct=col3&cd=1  Patient Resources on {{PAGENAME}}]
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[http://groups.google.com/groups/search?ie=UTF-8&oe=utf-8&q={{urlencode:{{#if:{{{1|}}}|{{{1}}}|{{PAGENAME}}}}}}&qt_s=Search Discussion Groups on {{PAGENAME}}]
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[http://www.google.com/search?hl=en&client=firefox-a&rls=org.mozilla:en-US:official&q={{urlencode:{{#if:{{{1|}}}|{{{1}}}|{{PAGENAME}}}}}}+more:patient_handouts&cx=disease_for_health_professionals&sa=N&oi=coopctx&resnum=0&ct=col1&cd=3 Patient Handouts on {{PAGENAME}}]
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[http://blogsearch.google.com/blogsearch?q={{urlencode:{{#if:{{{1|}}}|{{{1}}}|{{PAGENAME}}}}}}&ie=UTF-8&oe=utf-8&rls=org.mozilla:en-US:official&client=firefox-a&um=1&sa=N&tab=wb Blogs on {{PAGENAME}}]
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[http://news.google.com/news?q={{urlencode:{{#if:{{{1|}}}|{{{1}}}|{{PAGENAME}}}}}}&ie=UTF-8&oe=utf-8&rls=org.mozilla:en-US:official&client=firefox-a&um=1&sa=N&tab=wn {{PAGENAME}} in the News]
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[http://finance.google.com/finance?ie=UTF-8&oe=utf-8&q={{urlencode:{{#if:{{{1|}}}|{{{1}}}|{{PAGENAME}}}}}}&qt_s=Search&sa=N&tab=te {{PAGENAME}} in the Marketplace]
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</font size><small>[[{{PAGENAME}}#Dosing and Administration|Return to top]]</small><font size="4">
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==International Resources==
==FDA Package Insert==
[http://www.google.com/search?q={{urlencode:{{#if:{{{1|}}}|{{{1}}}|{{PAGENAME}}}}}}+en+espanol&ie=utf-8&oe=utf-8&aq=t&rls=org.mozilla:en-US:official&client=firefox-a {{PAGENAME}} en Español]
'''  [[Levofloxacin description|Description]]'''
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'''| [[Levofloxacin clinical pharmacology|Clinical Pharmacology]]'''
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'''| [[Levofloxacin microbiology|Microbiology]]'''
</font size><small>[[{{PAGENAME}}#Dosing and Administration|Return to top]]</small><font size="4">
'''| [[Levofloxacin indications and usage|Indications and Usage]]'''
<br>
'''| [[Levofloxacin contraindications|Contraindications]]'''
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'''| [[Levofloxacin warnings|Warnings]]'''
</font size>
'''| [[Levofloxacin precautions|Precautions]]'''
----
'''| [[Levofloxacin adverse reactions|Adverse Reactions]]'''
{{FDA}}
'''| [[Levofloxacin overdosage|Overdosage]]'''
'''| [[Levofloxacin clinical studies|Clinical Studies]]'''
'''| [[Levofloxacin dosage and administration|Dosage and Administration]]'''
'''| [[Levofloxacin how supplied|How Supplied]]'''
'''| [[Levofloxacin labels and packages|Labels and Packages]]'''


[[Category:Drugs]]
 
 
 
 
==References==
{{Reflist|2}}
http://www.fda.gov/downloads/Drugs/EmergencyPreparedness/BioterrorismandDrugPreparedness/UCM133684.pdf
[[Category:Antibiotics]]
[[Category:Wikinfect]]

Revision as of 04:42, 9 January 2014

Template:Levofloxacin Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1];Associate Editor(s)-in-Chief: Abdurahman Khalil, M.D. [2]

For patient information, click here.

Overview

Levofloxacin (trade names Levaquin (US), Tavanic (EU), and others) is a broad spectrum antibiotic of the fluoroquinolone drug class, 

and the levo isomer of its predecessor ofloxacin. Its spectrum of activity includes most strains of bacterial pathogens responsible for respiratory, urinary tract, gastrointestinal, and abdominal infections.


Category

Fluoroquinolone, third generation.

US Brand Names

LEVAQUIN®, LEVOFLOXACIN®.


FDA Package Insert

Description | Clinical Pharmacology | Microbiology | Indications and Usage | Contraindications | Warnings | Precautions | Adverse Reactions | Overdosage | Clinical Studies | Dosage and Administration | How Supplied | Labels and Packages



References

http://www.fda.gov/downloads/Drugs/EmergencyPreparedness/BioterrorismandDrugPreparedness/UCM133684.pdf

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