Doxycycline hyclate: Difference between revisions
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{{Doxycycline hyclate}} | |||
'''''For patient information, click <u>[[Doxycycline hyclate (patient information)|here]]'''''</u>. | |||
{{CMG}}; {{AE}} {{MM}} | |||
==Overview== | |||
==Category== | |||
[[Tetracycline]] | |||
==US Brand Names== | |||
DOXY 100 ''''''<sup>®</sup> | |||
==FDA Package Insert== | |||
''' [[Doxycycline hyclate description|Description]]''' | |||
'''| [[Doxycycline hyclate clinical pharmacology|Clinical Pharmacology]]''' | |||
'''| [[Doxycycline hyclate microbiology|Microbiology]]''' | |||
'''| [[Doxycycline hyclate indications and usage|Indications and Usage]]''' | |||
'''| [[Doxycycline hyclate contraindications|Contraindications]]''' | |||
'''| [[Doxycycline hyclate warnings and precautions|Warnings and Precautions]]''' | |||
'''| [[Doxycycline hyclate adverse reactions|Adverse Reactions]]''' | |||
'''| [[Doxycycline hyclate drug interactions|Drug Interactions]]''' | |||
'''| [[Doxycycline hyclate overdosage|Overdosage]]''' | |||
'''| [[Doxycycline hyclate dosage and administration|Dosage and Administration]]''' | |||
'''| [[Doxycycline hyclate how supplied|How Supplied]]''' | |||
'''| [[Doxycycline hyclate labels and packages|Labels and Packages]]''' | |||
==Mechanism of Action== | |||
As with related tetracycline antibiotics, demeclocycline acts by binding to the [[30S]] and [[50S]] ribosomal subunits, which impairs [[protein synthesis]] by bacteria. It is [[bacteriostatic]] (it impairs bacterial growth, but does not kill bacteria directly). | |||
It is not completely understood why demeclocycline impairs the action of [[antidiuretic hormone]], but is thought to block the binding of the hormone from its [[receptor (biochemistry)|receptor]].<ref>{{cite journal |doi=10.1056/NEJM197510302931809 |author=De Troyer A, Demanet JC |title=Correction of antidiuresis by demeclocycline |journal=N Engl J Med |volume=293 |issue=18 |pages=915–8 |year=1975 |pmid=170519}}</ref> | |||
==References== | |||
{{Reflist|2}} | |||
[[Category:Antibiotics]] | |||
[[Category:Wikinfect]] | |||
Revision as of 01:06, 9 January 2014
For patient information, click here.
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Mohamed Moubarak, M.D. [2]
Overview
Category
US Brand Names
DOXY 100 '®
FDA Package Insert
Description | Clinical Pharmacology | Microbiology | Indications and Usage | Contraindications | Warnings and Precautions | Adverse Reactions | Drug Interactions | Overdosage | Dosage and Administration | How Supplied | Labels and Packages
Mechanism of Action
As with related tetracycline antibiotics, demeclocycline acts by binding to the 30S and 50S ribosomal subunits, which impairs protein synthesis by bacteria. It is bacteriostatic (it impairs bacterial growth, but does not kill bacteria directly).
It is not completely understood why demeclocycline impairs the action of antidiuretic hormone, but is thought to block the binding of the hormone from its receptor.[1]
References
- ↑ De Troyer A, Demanet JC (1975). "Correction of antidiuresis by demeclocycline". N Engl J Med. 293 (18): 915–8. doi:10.1056/NEJM197510302931809. PMID 170519.