Silver sulfadiazine: Difference between revisions
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==Overview== | ==Overview== | ||
'''Silver sulfadiazine''' ([[International Nonproprietary Name|INN]], or '''silvadene''') is a [[topical]] [[sulfonamide (medicine)|sulfonamide]]/[[silver]]<ref name="pmid14512929">{{cite journal |author=Fisher NM, Marsh E, Lazova R |title=Scar-localized argyria secondary to silver sulfadiazine cream |journal=J. Am. Acad. Dermatol. |volume=49 |issue=4 |pages=730–2 |year=2003 |month=October |pmid=14512929 |doi= 10.1067/S0190-9622(02)61574-9|url=http://linkinghub.elsevier.com/retrieve/pii/S0190962202615749}}</ref> [[antibacterial]] used as a topical cream on [[burn]]s. Studies have found that silver sulfadiazine may increase healing times; and it is therefore not recommended by the authors of a [[Cochrane review]].<ref>{{cite journal |author=Wasiak J, Cleland H, Campbell F |title=Dressings for superficial and partial thickness burns |journal=Cochrane Database Syst Rev |volume= |issue=4 |pages=CD002106 |year=2008|pmid=18843629 |doi=10.1002/14651858.CD002106.pub3 |quote=The use of silver sulphadiazine (SSD) as a comparator on burn wounds for the full duration of treatment needs to be reconsidered, as a number of studies showed delays in time to wound healing and increased number of dressing applications in patients treated with SSD dressings}}</ref> | |||
Silver sulfadiazine is typically delivered in a 1% [[cream (pharmaceutical)|cream]] or [[aqueous]] [[suspension (chemistry)|suspension]]. Brand names include '''Silvadene''' (a [[genericized trademark]]), '''Silverex''', '''Silverol,''' '''Silvazine''', '''Flamazine''', '''Thermazene''', '''BurnHeal''', and '''SSD'''.<ref>http://www.drugs.com/mtm/ssd.html This source names Silvadene, SSD, SSD AF, Thermazene</ref> | |||
==Category== | ==Category== | ||
Revision as of 05:28, 9 January 2014
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Chetan Lokhande, M.B.B.S [2]
Overview
Silver sulfadiazine (INN, or silvadene) is a topical sulfonamide/silver[1] antibacterial used as a topical cream on burns. Studies have found that silver sulfadiazine may increase healing times; and it is therefore not recommended by the authors of a Cochrane review.[2]
Silver sulfadiazine is typically delivered in a 1% cream or aqueous suspension. Brand names include Silvadene (a genericized trademark), Silverex, Silverol, Silvazine, Flamazine, Thermazene, BurnHeal, and SSD.[3]
Category
US Brand Names
FDA Package Insert
Description | Clinical Pharmacology | Microbiology | Indications and Usage | Contraindications | Warnings and Precautions | Adverse Reactions | Drug Interactions | Overdosage | Clinical Studies | Dosage and Administration | How Supplied | Labels and Packages
Mechanism of Action
References
- ↑ Fisher NM, Marsh E, Lazova R (2003). "Scar-localized argyria secondary to silver sulfadiazine cream". J. Am. Acad. Dermatol. 49 (4): 730–2. doi:10.1067/S0190-9622(02)61574-9. PMID 14512929. Unknown parameter
|month=ignored (help) - ↑ Wasiak J, Cleland H, Campbell F (2008). "Dressings for superficial and partial thickness burns". Cochrane Database Syst Rev (4): CD002106. doi:10.1002/14651858.CD002106.pub3. PMID 18843629.
The use of silver sulphadiazine (SSD) as a comparator on burn wounds for the full duration of treatment needs to be reconsidered, as a number of studies showed delays in time to wound healing and increased number of dressing applications in patients treated with SSD dressings
- ↑ http://www.drugs.com/mtm/ssd.html This source names Silvadene, SSD, SSD AF, Thermazene