Sulfanilamide: Difference between revisions
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==Mechanism of Action== | ==Mechanism of Action== | ||
As a sulfonamide antibiotic, it functions by competitively inhibiting (i.e., by acting as a substrate analogue) enzymatic reactions involving [[para-aminobenzoic acid]] (PABA).<ref>Michael Kent, ''Advanced Biology,'' Oxford University Press, 2000, p. 46 ISBN 978-0-19-914195-1</ref> PABA is needed in enzymatic reactions that produce [[folic acid]] which acts as a coenzyme in the synthesis of purine, pyrimidine and other amino acids. | |||
==References== | ==References== | ||
Revision as of 08:34, 9 January 2014
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Mohamed Moubarak, M.D. [2]
Overview
Category
US Brand Names
AVC VAGINAL®
FDA Package Insert
Description | Clinical Pharmacology | Microbiology | Indications and Usage | Contraindications | Warnings and Precautions | Adverse Reactions | Overdosage | Dosage and Administration | How Supplied | Labels and Packages
Mechanism of Action
As a sulfonamide antibiotic, it functions by competitively inhibiting (i.e., by acting as a substrate analogue) enzymatic reactions involving para-aminobenzoic acid (PABA).[1] PABA is needed in enzymatic reactions that produce folic acid which acts as a coenzyme in the synthesis of purine, pyrimidine and other amino acids.
References
- ↑ Michael Kent, Advanced Biology, Oxford University Press, 2000, p. 46 ISBN 978-0-19-914195-1