Fosfomycin: Difference between revisions

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{{drugbox
__NOTOC__
| IUPAC_name        = [(2''R'',3''S'')-3-methyloxiran-2-yl]phosphonic acid
| image            = Fosfomycin skeletal.svg
| CAS_number        = 23155-02-4
| CAS_supplemental  = {{CAS|78964-85-9}} (tromethamine)
| ATC_prefix        = J01
| ATC_suffix        = XX01
| PubChem          = 446987
| DrugBank          = APRD00987
| C=3|H=7|O=4|P=1
| molecular_weight  = 138.059 g/mol
| bioavailability  = 30–37% (oral, fosfomycin tromethamine); varies with food intake
| protein_bound    = Nil
| metabolism        = Nil
| elimination_half-life = 5.7 hours (mean)
| excretion        = [[Kidney|Renal]] and fecal, unchanged
| pregnancy_AU      =  <!-- A / B1 / B2 / B3 / C / D / X -->
| pregnancy_US      = B
| pregnancy_category= 
| legal_AU          =  <!-- Unscheduled / S2 / S3 / S4 / S5 / S6 / S7 / S8 / S9 -->
| legal_CA          =  <!--            / Schedule I, II, III, IV, V, VI, VII, VIII -->
| legal_UK          =  <!-- GSL        / P      / POM / CD / Class A, B, C -->
| legal_US          = Rx-only
| legal_status      =
| routes_of_administration = Oral
}}
{{SI}}


{{Fosfomycin}}


{{CMG}}; {{AE}} {{AK}}
==Overview==
'''Fosfomycin''' (also known as phosphomycin and phosphonomycin) is a [[broad-spectrum antibiotic]] produced by certain ''[[Streptomyces]]'' species. It is indicated in the treatment of [[urinary tract infection]]s. It is usually administered as fosfomycin tromethamine, trade name Monurol.
'''Fosfomycin''' (also known as phosphomycin and phosphonomycin) is a [[broad-spectrum antibiotic]] produced by certain ''[[Streptomyces]]'' species. It is indicated in the treatment of [[urinary tract infection]]s. It is usually administered as fosfomycin tromethamine, trade name Monurol.


Fosfomycin is usually administered as a single dose.  
Fosfomycin is usually administered as a single dose.


==See also==
==US Brand Names ==
* [[Fosmidomycin]]


==External links==
MONUROL®
*[http://www.rxlist.com/cgi/generic/fosfomycin.htm Fosfomycin information at RxList]
==FDA Package Insert==


'''  [[Fosfomycin description|Description]]'''
'''| [[Fosfomycin clinical pharmacology|Clinical Pharmacology]]'''
'''| [[Fosfomycin microbiology|Microbiology]]'''
'''| [[Fosfomycin indications and usage|Indications and Usage]]'''
'''| [[Fosfomycin contraindications|Contraindications]]'''
'''| [[Fosfomycin warnings|Warnings]]'''
'''| [[Fosfomycin precautions|Precautions]]'''
'''| [[Fosfomycin adverse reactions|Adverse Reactions]]'''
'''| [[Fosfomycin overdosage|Overdosage]]'''
'''| [[Fosfomycin Information for Patients|Information for Patients]'''
'''| [[Fosfomycin dosage and administration|Dosage and Administration]]'''
'''| [[Fosfomycin how supplied|How Supplied]]'''
'''| [[Fosfomycin labels and packages|Labels and Packages]]'''


{{Other antibacterials}}
==References==
 
{{Reflist|2}}
http://www.accessdata.fda.gov/drugsatfda_docs/label/2008/050717s005lbl.pdf
[[Category:Antibiotics]]
[[Category:Antibiotics]]
 
[[Category:Wikinfect]]
 
[[ru:Фосфомицин]]
 
{{WH}}
{{WS}}

Revision as of 15:28, 9 January 2014


Fosfomycin
MONUROL® FDA Package Insert
Description
Clinical Pharmacology
Microbiology
Indications and Usage
Contraindications
Warnings
Precautions
Adverse Reactions
Overdosage
Clinical Studies
Dosage and Administration
How Supplied
Labels and Packages

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Abdurahman Khalil, M.D. [2]

Overview

Fosfomycin (also known as phosphomycin and phosphonomycin) is a broad-spectrum antibiotic produced by certain Streptomyces species. It is indicated in the treatment of urinary tract infections. It is usually administered as fosfomycin tromethamine, trade name Monurol.

Fosfomycin is usually administered as a single dose.

US Brand Names

MONUROL®

FDA Package Insert

Description | Clinical Pharmacology | Microbiology | Indications and Usage | Contraindications | Warnings | Precautions | Adverse Reactions | Overdosage | [[Fosfomycin Information for Patients|Information for Patients] | Dosage and Administration | How Supplied | Labels and Packages

References

http://www.accessdata.fda.gov/drugsatfda_docs/label/2008/050717s005lbl.pdf