Amyl nitrite overdosage: Difference between revisions

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#REDIRECT [[Amyl nitrite#Overdosage]]
{{Amyl nitrite}}
{{CMG}}; {{AE}} {{PB}}
 
==Overdosage==
 
 
===Symptons===
Inhaled doses of 5 to 10 drops of amyl nitrite may cause violent flushing of the face, accompanied by a feeling of imminent bursting of the head and very excessive heart action. The inhalation of larger amounts may produce a feeling of suffocation and muscular weakness. Symptons comparable to shock may be produced such as weakness, restlessness, sweating, [[pallor]], [[nausea]], [[vomiting]], [[syncope]] and [[incontinence]] attributable to pooling of blood in the postarteriolar vessels and failure of the venous blood to return to the heart.
 
===Treatment===
Measures which facilitate venous return such as head low posture, deep breathing and movement of extremities may be used. The use of [[epinephrine]] aggravates the shock like reaction. [[Methylene blue]] should be injected for treatment of severe [[methemoglobinemia]] with [[dyspnea]]. For treating [[cyanide poisoning]], [[methylene blue]] is contraindicated where nitrites cause iatrogenic [[methemoglobinemia]].<ref name="dailymed.nlm.nih.gov">{{Cite web  | last =  | first =  | title = AMYL NITRITE INHALANT [JAMES ALEXANDER CORPORATION] | url = http://dailymed.nlm.nih.gov/dailymed/lookup.cfm?setid=c1b6e536-df5f-4f76-8e3c-6dc2f1e9975e | publisher =  | date =  | accessdate = 30 January 2014 }}</ref>
 
==References==
 
{{Reflist|2}}
 
[[Category:Drugs]]

Latest revision as of 22:36, 21 July 2014