Acebutolol overdosage: Difference between revisions

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__NOTOC__
#REDIRECT [[Acebutolol#Overdosage]]
{{Acebutolol}}
{{CMG}}; {{AE}} {{SS}}
 
==Overdosage==
 
No specific information on emergency treatment of overdosage is available for Sectral. However, overdosage with other β-blocking agents has been accompanied by extreme [[bradycardia]], advanced atrioventricular block, intraventricular conduction defects, hypotension, severe congestive heart failure, seizures, and in susceptible patients, [[bronchospasm]] and [[hypoglycemia]]. Although specific information on the emergency treatment of Sectral overdose is not available, on the basis of the pharmacological actions and the observations in treating overdoses with other β-blockers, the following general measures should be considered:
 
Empty stomach by emesis or lavage.
'''[[bradycardia]]''': IV [[atropine]] (1 to 3 mg in divided doses). If antivagal response is inadequate, administer isoproterenol cautiously since larger than usual doses of isoproterenol may be required.
Persistent hypotension in spite of correction of [[bradycardia]]: Administer vasopressor (e.g., [[epinephrine]], [[levarterenol]], [[dopamine]], or [[dobutamine]]) with frequent monitoring of blood pressure and pulse rate.
'''[[Bronchospasm]]''': A theophylline derivative, such as aminophylline and/or parenteral β2-stimulant, such as [[terbutaline]].
Cardiac failure: Digitalize the patient and/or administer a [[diuretic]]. It has been reported that glucagon is useful in this situation.
 
Sectral is dialyzable.
 
<ref name="dailymed.nlm.nih.gov">{{Cite web  | last =  | first =  | title = SECTRAL (ACEBUTOLOL HYDROCHLORIDE) CAPSULE [PROMIUS PHARMA, LLC] | url = http://dailymed.nlm.nih.gov/dailymed/lookup.cfm?setid=7eee95bf-0452-4d6e-9712-33403768695a | publisher =  | date =  | accessdate = 3 February 2014 }}</ref>
 
==References==
 
{{Reflist|2}}
 
[[Category:Beta blockers]]
[[Category:Cardiovascular Drugs]]
[[Category:Drugs]]
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Latest revision as of 14:57, 21 July 2014