Lopressor/contraindications: Difference between revisions

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{{CMG}}
__NOTOC__
__NOTOC__
==List of contraindications==
{{Metoprolol}}
<br>
{{CMG}}; {{AE}} {{AZ}}
<font size="4">[[Metoprolol contraindications#Hypertension and Angina|Hypertension and Angina]]</font>
<br>
<br>
<font size="4">[[Metoprolol contraindications#Hypersensitivity|Hypersensitivity]]</font>
<br>
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<font size="4">[[Metoprolol contraindications#Sick-sinus syndrome|Sick-sinus syndrome]]</font>
<br>
<br>
<font size="4">[[Metoprolol contraindications#Pheochromocytoma|Pheochromocytoma]]</font>
<br>
<br>
<font size="4">[[Metoprolol contraindications#Myocardial Infarction|Myocardial Infarction]]</font>
<br>
<br>
------------
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===Hypertension and Angina===


Metoprolol tartrate tablets are contraindicated in [[sinus bradycardia]], [[heart block]] greater than first degree, [[cardiogenic shock]], and overt [[cardiac failure]]


''[[Metoprolol contraindications#List of contraindications|Return to top]]''
<br>


===Hypersensitivity===
<ref name="dailymed.nlm.nih.gov">{{Cite web  | last = | first = | title = LOPRESSOR (METOPROLOL TARTRATE) TABLET [NOVARTIS PHARMACEUTICALS CORPORATION] | url =http://dailymed.nlm.nih.gov/dailymed/lookup.cfm?setid=bb05420c-fd24-4672-9f62-fdd313819287 | publisher =  | date =  | accessdate = }}</ref>


Hypersensitivity to Metoprolol and related derivatives, or to any of the excipients; [[hypersensitivity]] to other [[beta-blockers]] (cross sensitivity between [[beta-blockers]] can occur).
==References==
 
{{Reflist}}
''[[Metoprolol contraindications#List of contraindications|Return to top]]''
<br>
 
===Sick-sinus syndrome===
 
Severe peripheral arterial circulatory disorders.
 
''[[Metoprolol contraindications#List of contraindications|Return to top]]''
<br>
 
===Pheochromocytoma===
''[[Metoprolol contraindications#List of contraindications|Return to top]]''
<br>
===Myocardial Infarction===
Metoprolol tartrate tablets are contraindicated in patients with a heart rate < 45 beats/min; second- and third-degree heart block; significant first-degree heart block (P-R interval ≥ 0.24 sec); systolic blood pressure < 100 mmHg; or moderate-to-severe cardiac failure.
 
''[[Metoprolol contraindications#List of contraindications|Return to top]]''
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<br>
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{{FDA}}
{{FDA}}


[[Category:Drugs]]
[[Category:Drugs]]

Revision as of 23:39, 3 February 2014

Metoprolol
Clinical data
Trade namesLopressor, Toprol-xl
AHFS/Drugs.comMonograph
MedlinePlusa682864
[[Regulation of therapeutic goods |Template:Engvar data]]
Pregnancy
category
  • AU: C
  • US: C (Risk not ruled out)
Routes of
administration		Oral, IV
ATC code
Legal status
Legal status
  • In general: ℞ (Prescription only)
Pharmacokinetic data
Bioavailability12%
MetabolismHepatic via CYP2D6, CYP3A4
Elimination half-life3-7 hours
ExcretionRenal
Identifiers
CAS Number
PubChem CID
IUPHAR/BPS
DrugBank
ChemSpider
UNII
KEGG
ChEBI
ChEMBL
E number{{#property:P628}}
ECHA InfoCard{{#property:P2566}}Lua error in Module:EditAtWikidata at line 36: attempt to index field 'wikibase' (a nil value).
Chemical and physical data
FormulaC15H25NO3
Molar mass267.364 g/mol
3D model (JSmol)
Melting point120 °C (248 °F)
  (verify)

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Ahmed Zaghw, M.D. [2]


[1]

References

  1. ↑ "LOPRESSOR (METOPROLOL TARTRATE) TABLET [NOVARTIS PHARMACEUTICALS CORPORATION]".

Adapted from the FDA Package Insert.

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