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| __NOTOC__
| | #REDIRECT [[Penbutolol#Overdosage]] |
| {{Penbutolol}}
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| {{CMG}}; {{AE}} {{SS}}
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| ==Overdosage==
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| There is no actual experience with levatol® overdose. The signs and symptoms that would be expected with overdosage of ß-adrenergic receptor antagonists are symptomatic [[bradycardia]], [[hypotension]], bronchospasm, and acute cardiac failure. In addition to discontinuation of levatol®, gastric emptying, and close observation of the patient, the following measures might be considered as appropriate:
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| Excessive [[bradycardia]]: Administer atropine sulfate to induce vagal blockade. If [[bradycardia]] persists, intravenous [[isoproterenol]] hydrochloride may be administered cautiously; larger than usual doses may be needed. In refractory cases, the use of a transvenous cardiac pacemaker may be necessary.
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| [[hypotension]]: Sympathomimetic drug therapy, such as [[dopamine]], [[dobutamine]], or [[levarterenol]], may be considered if [[hypotension]] persists despite correction of [[bradycardia]]. In refractory cases, administration of glucagon hydrochloride has been reported to be useful.
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| Bronchospasm: A ß-2-agonist or [[isoproterenol]] hydrochloride may be administered. Additional therapy with [[aminophylline]] may be considered.
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| Acute Cardiac Failure: Institute conventional therapy immediately. Intravenous administration of [[dobutamine]] and glucagon hydrochloride has been reported to be useful.
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| Heart Block (Second or Third Degree): [[isoproterenol]] hydrochloride or a transvenous cardiac pacemaker may be used.
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| <ref name="dailymed.nlm.nih.gov">{{Cite web | last = | first = | title = LEVATOL (PENBUTOLOL SULFATE) TABLET [ACTIENT PHARMACEUTICALS, LLC] | url = http://dailymed.nlm.nih.gov/dailymed/lookup.cfm?setid=d241fc80-2c55-4dbb-bdb2-44f731afa137 | publisher = | date = | accessdate = 4 February 2014 }}</ref>
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| ==References==
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| {{Reflist|2}}
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| [[Category:Beta blockers]]
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| [[Category:Cardiovascular Drugs]]
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| [[Category:Drugs]]
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