Topiramate use in specific populations: Difference between revisions
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* Renal impairment: In renally impaired patients (creatinine clearance less than 70 mL/min/1.73 m2), one-half of the adult dose is recommended. | |||
* Patients undergoing hemodialysis: Topiramate is cleared by hemodialysis. Dosage adjustment is necessary to avoid rapid drops in topiramate plasma concentration during hemodialysis. | |||
* Pregnancy: Increased risk of cleft lip and/or palate. Pregnancy registry available. | |||
* Nursing mothers: Caution should be exercised when administered to a nursing mother . | |||
* Geriatric use: Dosage adjustment may be necessary for elderly with impaired renal function.<ref name="dailymed.nlm.nih.gov">{{Cite web | last = | first = | title = TOPIRAMATE (TOPIRAMATE ) TABLET, FILM COATED [AUROBINDO PHARMA LIMITED] | url = http://dailymed.nlm.nih.gov/dailymed/lookup.cfm?setid=32b48ea0-a215-43b8-83b4-a5435a686d68 | publisher = | date = | accessdate = 6 February 2014 }}</ref> | |||
==References== | ==References== | ||
Revision as of 23:19, 6 February 2014
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Pratik Bahekar, MBBS [2]
For patient information, click here.
Specific Populations
- Renal impairment: In renally impaired patients (creatinine clearance less than 70 mL/min/1.73 m2), one-half of the adult dose is recommended.
- Patients undergoing hemodialysis: Topiramate is cleared by hemodialysis. Dosage adjustment is necessary to avoid rapid drops in topiramate plasma concentration during hemodialysis.
- Pregnancy: Increased risk of cleft lip and/or palate. Pregnancy registry available.
- Nursing mothers: Caution should be exercised when administered to a nursing mother .
- Geriatric use: Dosage adjustment may be necessary for elderly with impaired renal function.[1]
References
- ↑ "TOPIRAMATE (TOPIRAMATE ) TABLET, FILM COATED [AUROBINDO PHARMA LIMITED]". Retrieved 6 February 2014.