|
|
| Line 1: |
Line 1: |
| __NOTOC__
| | #REDIRECT [[Pindolol#Overdosage]] |
| {{Pindolol}}
| |
| {{CMG}}
| |
| | |
| ==Overdosage==
| |
| | |
| No specific information on emergency treatment of overdosage is available. Therefore, on the basis of the pharmacologic actions of Visken®(pindolol), the following general measures should be employed as appropriate in addition to gastric lavage:
| |
| | |
| <u>'''Excessive Bradycardia'''</u>: administer atropine; if there is no response to vagal blockade, administer isoproterenol cautiously.
| |
| | |
| <u>'''Cardiac Failure'''</u>: digitalize the patient and/or administer diuretic. It has been reported that glucagon may be useful in this situation.
| |
| | |
| <u>'''Hypotension'''</u>: administer vasopressors, e.g., epinephrine or levarterenol, with serial monitoring of blood pressure. (There is evidence that epinephrine may be the drug of choice.)
| |
| | |
| <u>'''Bronchospasm'''</u>: administer a beta2 stimulating agent such as isoproterenol and/or a theophylline derivative.
| |
| | |
| A case of an acute overdosage has been reported with an intake of 500 mg of Visken® (pindolol) by a hypertensive patient. Blood pressure increased and heart rate was ≥80 beats/min. Recovery was uneventful. In another case, 250 mg of Visken® (pindolol) was taken with 150 mg diazepam and 50 mg nitrazepam, producing coma and hypotension. The patient recovered in 24 hours.<ref name="dailymed.nlm.nih.gov">{{Cite web | last = | first = | title = VISKEN (PINDOLOL) TABLET [NOVARTIS PHARMACEUTICALS CORPORATION] | url = http://dailymed.nlm.nih.gov/dailymed/lookup.cfm?setid=07fe9cc3-1ef2-420c-b45d-7f1e894b6ef9 | publisher = | date = | accessdate = }}</ref>
| |
| | |
| ==References==
| |
| {{Reflist}}
| |
| | |
| {{FDA}}
| |
| | |
| [[Category:Cardiovascular Drugs]]
| |
| [[Category:Beta blockers]]
| |
| [[Category:Drugs]]
| |