Template:Benazepril: Difference between revisions

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{| style="margin: 0 0 3em 3em; border: 1px solid #696969; float: right; width:20em" cellpadding="0" cellspacing="0";
{{Drugbox
! style="padding: 0 5px; font-size: 100%; background:#F8F8FF" align=center | '''''[[Benazepril|{{fontcolor|#6C7B8B|Benazepril}}]]'''''
| verifiedrevid = 459529583
|-
| IUPAC_name = 2-[(3''S'')-3-{[(2''S'')-1-ethoxy-1-oxo-4-phenylbutan-2-yl]amino}-
! style="padding: 0 5px; font-size: 85%; background:#F5F5F5" align=left | LOTENSIN<sup>®</sup> FDA Package Insert
| image = Benazepril structure.png
|-
 
! style="font-size: 80%; padding: 0 5px; background: #DCDCDC" align=left | [[Benazepril indications and usage|Indications and Usage]]
<!--Clinical data-->
|-
| tradename = Lotensin
! style="font-size: 80%; padding: 0 5px; background: #DCDCDC" align=left | [[Benazepril dosage and administration|Dosage and Administration]]
| Drugs.com = {{drugs.com|monograph|benazepril-hydrochloride}}
|-
| MedlinePlus = a692011
! style="font-size: 80%; padding: 0 5px; background: #DCDCDC" align=left | [[Benazepril contraindications|Contraindications]]
| pregnancy_category = D
|-
| legal_status = Rx-only
! style="font-size: 80%; padding: 0 5px; background: #DCDCDC" align=left | [[Benazepril warnings and precautions|Warnings and Precautions]]
| routes_of_administration = Oral
|-
 
! style="font-size: 80%; padding: 0 5px; background: #DCDCDC" align=left | [[Benazepril adverse reactions|Adverse Reactions]]
<!--Pharmacokinetic data-->
|-
| bioavailability = 
! style="font-size: 80%; padding: 0 5px; background: #DCDCDC" align=left | [[Benazepril drug interactions|Drug Interactions]]
| protein_bound = 96.7%
|-
| metabolism = [[Liver|Hepatic]] [[glucuronidation]]
! style="font-size: 80%; padding: 0 5px; background: #DCDCDC" align=left | [[Benazepril overdosage|Overdosage]]
| elimination_half-life = 10-11 hours
|-
| excretion = [[Kidney|Renal]] and biliary
! style="font-size: 80%; padding: 0 5px; background: #DCDCDC" align=left | [[Benazepril description|Description]]
 
|-
<!--Identifiers-->
! style="font-size: 80%; padding: 0 5px; background: #DCDCDC" align=left | [[Benazepril clinical pharmacology|Clinical Pharmacology]]
| CASNo_Ref = {{cascite|correct|CAS}}
|-
| CAS_number_Ref = {{cascite|correct|??}}
! style="font-size: 80%; padding: 0 5px; background: #DCDCDC" align=left | [[Benazepril clinical studies|Clinical Studies]]
| CAS_number = 86541-75-5
|-
| ATC_prefix = C09
! style="font-size: 80%; padding: 0 5px; background: #DCDCDC" align=left | [[Benazepril how supplied storage and handling|How Supplied/Storage and Handling]]
| ATC_suffix = AA07
|-
| PubChem = 5362124
! style="font-size: 80%; padding: 0 5px; background: #DCDCDC" align=left | [[Benazepril patient counseling information|Patient Counseling Information]]
| DrugBank_Ref = {{drugbankcite|correct|drugbank}}
|-
| DrugBank = DB00542
! style="font-size: 80%; padding: 0 5px; background: #DCDCDC" align=left | [[Benazepril labels and packages|Labels and Packages]]
| ChemSpiderID_Ref = {{chemspidercite|correct|chemspider}}
|-
| ChemSpiderID = 4514935
! style="padding: 0 5px; font-size: 85%; background:#F5F5F5" align=left | Clinical Trials on Benazepril
| UNII_Ref = {{fdacite|correct|FDA}}
|-
| UNII = UDM7Q7QWP8
! style="font-size: 80%; padding: 0 5px; background: #DCDCDC" align=left | [http://clinicaltrials.gov/search/open/condition={{urlencode:{{#if:{{{1|}}}|{{{1}}}|{{PAGENAME}}}}}} ClinicalTrials.gov]
| ChEBI_Ref = {{ebicite|correct|EBI}}
|-
| ChEBI = 3011
|}
| ChEMBL_Ref = {{ebicite|correct|EBI}}
| ChEMBL = 838
 
<!--Chemical data-->
| C=24 | H=28 | N=2 | O=5
| molecular_weight = 424.49 g/mol
| smiles = O=C(OCC)[C@@H](N[C@@H]2C(=O)N(c1ccccc1CC2)CC(=O)O)CCc3ccccc3
| InChI = 1/C24H28N2O5/c1-2-31-24(30)20(14-12-17-8-4-3-5-9-17)25-19-15-13-18-10-6-7-11-21(18)26(23(19)29)16-22(27)28/h3-11,19-20,25H,2,12-16H2,1H3,(H,27,28)/t19-,20-/m0/s1
| InChIKey = XPCFTKFZXHTYIP-PMACEKPBBT
| StdInChI_Ref = {{stdinchicite|correct|chemspider}}
| StdInChI = 1S/C24H28N2O5/c1-2-31-24(30)20(14-12-17-8-4-3-5-9-17)25-19-15-13-18-10-6-7-11-21(18)26(23(19)29)16-22(27)28/h3-11,19-20,25H,2,12-16H2,1H3,(H,27,28)/t19-,20-/m0/s1
| StdInChIKey_Ref = {{stdinchicite|correct|chemspider}}
| StdInChIKey = XPCFTKFZXHTYIP-PMACEKPBSA-N
}}

Revision as of 15:52, 24 March 2014

Benazepril
Clinical data
Trade namesLotensin
AHFS/Drugs.comMonograph
MedlinePlusa692011
Pregnancy
category
  • D
Routes of
administration		Oral
ATC code
Legal status
Legal status
  • In general: ℞ (Prescription only)
Pharmacokinetic data
Protein binding96.7%
MetabolismHepatic glucuronidation
Elimination half-life10-11 hours
ExcretionRenal and biliary
Identifiers
CAS Number
PubChem CID
DrugBank
ChemSpider
UNII
ChEBI
ChEMBL
E number{{#property:P628}}
ECHA InfoCard{{#property:P2566}}Lua error in Module:EditAtWikidata at line 36: attempt to index field 'wikibase' (a nil value).
Chemical and physical data
FormulaC24H28N2O5
Molar mass424.49 g/mol
3D model (JSmol)
  (verify)
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