Lovastatin indications and usage: Difference between revisions

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==Indications and Usage==
==Indications and Usage==


===INDICATIONS AND USAGE===
Therapy with lipid-altering agents should be one component of multiple risk factor intervention in individuals who require modifications of their lipid profile. Drug therapy is recommended as an adjunct to a diet restricted in saturated fat and [[cholesterol]] only when the response to diet and other non-pharmacological measures has been inadequate.


Therapy with lipid-altering agents should be one component of multiple risk factor intervention in individuals who require modifications of their lipid profile. Drug therapy is recommended as an adjunct to a diet restricted in saturated fat and cholesterol only when the response to diet and other non-pharmacological measures has been inadequate.
===Prevention of Coronary Heart Disease===


1.1  Prevention of Coronary Heart Disease
In patients without symptomatic [[coronary heart disease]] ([[CHD]]), but at high risk, Altoprev® is indicated to reduce the risk of:


In patients without symptomatic coronary heart disease (CHD), but at high risk, Altoprev® is indicated to reduce the risk of:
[[Myocardial infarction]]
 
[[Unstable angina]]
Myocardial infarction
Unstable angina
Coronary revascularization procedures
Coronary revascularization procedures


Coronary Heart Disease  
[[Coronary Heart Disease]]
Altoprev® is indicated to slow the progression of coronary atherosclerosis in patients with coronary heart disease as part of a treatment strategy to lower Total-C and LDL-C to target levels.
Altoprev® is indicated to slow the progression of coronary [[atherosclerosis]] in patients with coronary heart disease as part of a treatment strategy to lower Total-C and LDL-C to target levels.
 
1.2  Hyperlipidemia


Altoprev® is indicated as an adjunct to diet for the reduction of elevated Total-C, LDL-C, Apo B, and TG, and to increase HDL-C in patients with primary hypercholesterolemia (heterozygous familial and non-familial) and mixed dyslipidemia (Fredrickson types IIa and IIb).
===Hyperlipidemia===


1.3  Limitations of Use
Altoprev® is indicated as an adjunct to diet for the reduction of elevated Total-C, LDL-C, Apo B, and TG, and to increase HDL-C in patients with primary [[hypercholesterolemia]] (heterozygous familial and non-familial) and mixed [[dyslipidemia]] (Fredrickson types IIa and IIb).


Altoprev® has not been studied in Fredrickson Types I, III, and V.
===Limitations of Use===


<ref name="dailymed.nlm.nih.gov">{{Cite web  | last =  | first =  | title = ALTOPREV (LOVASTATIN) TABLET, EXTENDED RELEASE [SHIONOGI INC.] | url = http://dailymed.nlm.nih.gov/dailymed/lookup.cfm?setid=e8b6ccc2-e6e7-45fd-ab66-c312bcbe2b01 | publisher =  | date =  | accessdate = 13 February 2014 }}</ref>
Altoprev® has not been studied in Fredrickson Types I, III, and V.<ref name="dailymed.nlm.nih.gov">{{Cite web  | last =  | first =  | title = ALTOPREV (LOVASTATIN) TABLET, EXTENDED RELEASE [SHIONOGI INC.] | url = http://dailymed.nlm.nih.gov/dailymed/lookup.cfm?setid=e8b6ccc2-e6e7-45fd-ab66-c312bcbe2b01 | publisher =  | date =  | accessdate = 13 February 2014 }}</ref>


==References==
==References==

Revision as of 23:52, 13 February 2014

Lovastatin
ALTOPREV® FDA Package Insert
Indications and Usage
Dosage and Administration
Dosage Forms and Strengths
Contraindications
Warnings and Precautions
Adverse Reactions
Drug Interactions
Use in Specific Populations
Overdosage
Description
Clinical Pharmacology
Nonclinical Toxicology
Clinical Studies
How Supplied/Storage and Handling
Labels and Packages
Clinical Trials on Lovastatin
ClinicalTrials.gov

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Sheng Shi, M.D. [2]

Indications and Usage

Therapy with lipid-altering agents should be one component of multiple risk factor intervention in individuals who require modifications of their lipid profile. Drug therapy is recommended as an adjunct to a diet restricted in saturated fat and cholesterol only when the response to diet and other non-pharmacological measures has been inadequate.

Prevention of Coronary Heart Disease

In patients without symptomatic coronary heart disease (CHD), but at high risk, Altoprev® is indicated to reduce the risk of:

Myocardial infarction Unstable angina Coronary revascularization procedures

Coronary Heart Disease Altoprev® is indicated to slow the progression of coronary atherosclerosis in patients with coronary heart disease as part of a treatment strategy to lower Total-C and LDL-C to target levels.

Hyperlipidemia

Altoprev® is indicated as an adjunct to diet for the reduction of elevated Total-C, LDL-C, Apo B, and TG, and to increase HDL-C in patients with primary hypercholesterolemia (heterozygous familial and non-familial) and mixed dyslipidemia (Fredrickson types IIa and IIb).

Limitations of Use

Altoprev® has not been studied in Fredrickson Types I, III, and V.[1]

References

  1. "ALTOPREV (LOVASTATIN) TABLET, EXTENDED RELEASE [SHIONOGI INC.]". Retrieved 13 February 2014.

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