Pravastatin: Difference between revisions
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{{Pravastatin}} | {{Pravastatin}} | ||
{{CMG}}; {{AE}} | {{CMG}}; {{AE}} {{SS}} | ||
'''''For patient information about Pravastatin, click [[Pravastatin (patient information)|here]].''''' | '''''For patient information about Pravastatin, click [[Pravastatin (patient information)|here]].''''' | ||
{{SB}} | {{SB}} PRAVACHOL<sup>®</sup> | ||
==Overview== | ==Overview== | ||
'''Pravastatin''' (marketed as '''Pravachol''' or '''Selektine''') is a member of the drug class of [[statin]]s, used in combination with diet, exercise, and weight-loss for lowering [[cholesterol]] and preventing [[cardiovascular disease]]. | |||
==Category== | ==Category== | ||
Statins,Bristol-Myers Squibb,Diols,Carboxylic acids,Carboxylate esters,Category:Naphthalenes,Cardiovascular Drugs. | |||
==FDA Package Insert== | ==FDA Package Insert== | ||
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==Mechanism of Action== | ==Mechanism of Action== | ||
Pravastatin is a reversible inhibitor of 3-hydroxy-3-methylglutaryl-coenzyme A (HMG-CoA) reductase, the enzyme that catalyzes the conversion of HMG-CoA to mevalonate, an early and rate limiting step in the biosynthetic pathway for [[cholesterol]]. In addition, pravastatin reduces VLDL and TG and increases HDL-C. | |||
==Interaction with Alcohol== | |||
Caution should be exercised when pravastatin is administered to patients who are heavy users of alcohol. | |||
==References== | ==References== | ||
{{Reflist|2}} | {{Reflist|2}} | ||
[[Category:Statins]] | |||
[[Category:Bristol-Myers Squibb]] | |||
[[Category:Diols]] | |||
[[Category:Carboxylic acids]] | |||
[[Category:Carboxylate esters]] | |||
[[Category:Naphthalenes]] | |||
[[Category:Cardiovascular Drugs]] | [[Category:Cardiovascular Drugs]] | ||
[[Category:Drugs]] | [[Category:Drugs]] | ||
Revision as of 03:41, 18 February 2014
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Sheng Shi, M.D. [2]
For patient information about Pravastatin, click here.
Synonyms / Brand Names: PRAVACHOL®
Overview
Pravastatin (marketed as Pravachol or Selektine) is a member of the drug class of statins, used in combination with diet, exercise, and weight-loss for lowering cholesterol and preventing cardiovascular disease.
Category
Statins,Bristol-Myers Squibb,Diols,Carboxylic acids,Carboxylate esters,Category:Naphthalenes,Cardiovascular Drugs.
FDA Package Insert
Indications and Usage | Dosage and Administration | Dosage Forms and Strengths | Contraindications | Warnings and Precautions | Adverse Reactions | Drug Interactions | Use in Specific Populations | Overdosage | Description | Clinical Pharmacology | Nonclinical Toxicology | Clinical Studies | How Supplied/Storage and Handling | Patient Counseling Information | Labels and Packages
Mechanism of Action
Pravastatin is a reversible inhibitor of 3-hydroxy-3-methylglutaryl-coenzyme A (HMG-CoA) reductase, the enzyme that catalyzes the conversion of HMG-CoA to mevalonate, an early and rate limiting step in the biosynthetic pathway for cholesterol. In addition, pravastatin reduces VLDL and TG and increases HDL-C.
Interaction with Alcohol
Caution should be exercised when pravastatin is administered to patients who are heavy users of alcohol.