Diverticulitis resident survival guide: Difference between revisions

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{{familytree | | | | B01 | | | | | | | | | | | | B02 | | | | | | | | | | B01= '''Uncomplicated'''  | B02= '''Complicated'''<ref name="pmid16885694">{{cite journal| author=Floch MH| title=A hypothesis: is diverticulitis a type of inflammatory bowel disease? | journal=J Clin Gastroenterol | year= 2006 | volume= 40 Suppl 3 | issue=  | pages= S121-5 | pmid=16885694 | doi=10.1097/01.mcg.0000225502.29498.ba | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=16885694  }} </ref>  }}
{{familytree | | | | B01 | | | | | | | | | | | | B02 | | | | | | | | | | B01= '''Uncomplicated'''  | B02= '''Complicated'''<ref name="pmid16885694">{{cite journal| author=Floch MH| title=A hypothesis: is diverticulitis a type of inflammatory bowel disease? | journal=J Clin Gastroenterol | year= 2006 | volume= 40 Suppl 3 | issue=  | pages= S121-5 | pmid=16885694 | doi=10.1097/01.mcg.0000225502.29498.ba | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=16885694  }} </ref>  }}
{{familytree | | |,|-|^|-|.| | | | | | | | | | | |!| | | | | | | | | | | }}
{{familytree | | |,|-|^|-|.| | | | | | | | | | | |!| | | | | | | | | | | }}
{{familytree | | C01 | | C02 | | | | | | | | | | C03 | | | | | | | | | | C01= '''Outpatient''' <div style="float: left; text-align: left; padding:1em;">
{{familytree | | C01 | | C02 | | | | | | | | | | C03 | | | | | | | | | | C01='''Outpatient''' <div style="float: left; text-align: left; padding:1em;">
  ❑ Inmunocompetent patient <br> ❑Tolerated oral intake<br> ❑Single episode<br> ❑Mild to moderate pain </div>
  ❑ Inmunocompetent patient <br> ❑Tolerated oral intake<br> ❑Single episode<br> ❑Mild to moderate pain </div>
| C02= '''Hospitalized''' <div style="float: left; text-align: left; padding:1em;"> ❑Unable to tolerate oral intake <br> ❑Severe pain <br> ❑Inmunocompromised patients </div>
| C02= '''Hospitalized''' <div style="float: left; text-align: left; padding:1em;"> ❑Unable to tolerate oral intake <br> ❑Severe pain <br> ❑Inmunocompromised patients </div>
| C03= <div style="float: left; text-align: left; padding:1em;"> ❑[[Abscess]] <br> ❑[[Phlegmon]] <br> ❑[[Obstruction]] <br> ❑[[Fistula|Fistulization]] <br> ❑[[Bleeding]] <br> ❑[[Sepsis]] </div> }}
| C03= <div style="float: left; text-align: left; padding:1em;"> ❑[[Abscess]] <br> ❑[[Phlegmon]] <br> ❑[[Obstruction]] <br> ❑[[Fistula|Fistulization]] <br> ❑[[Bleeding]] <br> ❑[[Sepsis]] </div> }}
{{familytree | | |!| | | |!| | | | | | | | | | | |!| | | | | | | | | | | }}
{{familytree | | |!| | | |!| | | | | | | | | | | |!| | | | | | | | | | | }}
{{familytree | | D01 | | D02 | | | | | | | | | | D03 | | | | | | | | | | D01= '''Medical Treatment'''<ref name="pmid18003962">{{cite journal| author=Jacobs DO| title=Clinical practice. Diverticulitis. | journal=N Engl J Med | year= 2007 | volume= 357 | issue= 20 | pages= 2057-66 | pmid=18003962 | doi=10.1056/NEJMcp073228 | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=18003962  }} </ref> <div style="float: left; text-align: left; padding:1em;"> ❑[[Metronidazole]] (500mg / 6 - 8 hrs) + [[Quinolone]]   (e.g [[Ciprofloxacin]] 500 - 700mg / 12hrs) <br>
{{familytree | | D01 | | D02 | | | | | | | | | | D03 | | | | | | | | | | D01= '''Medical Treatment'''<ref name="pmid18003962">{{cite journal| author=Jacobs DO| title=Clinical practice. Diverticulitis. | journal=N Engl J Med | year= 2007 | volume= 357 | issue= 20 | pages= 2057-66 | pmid=18003962 | doi=10.1056/NEJMcp073228 | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=18003962  }} </ref> <div style="float: left; text-align: left; padding:1em;"> Oral regimens <br>
❑[[Metronidazole]] (500mg / 6 - 8 hrs) + [[Quinolone]] (e.g. [[Ciprofloxacin]] 500 - 700mg / 12hrs) <br>
❑[[Metronidazole]] (500mg / 6 - 8 hrs) + [[Trimethoprim]] (160mg / 12 hrs) - [[Sulfamethoxazole]] (800mg / 12hrs)<br>
❑[[Metronidazole]] (500mg / 6 - 8 hrs) + [[Trimethoprim]] (160mg / 12 hrs) - [[Sulfamethoxazole]] (800mg / 12hrs)<br>
❑[[Amoxicillin]]- clavulanate (875mg / 12hrs)
❑[[Amoxicillin]]- clavulanate (875mg / 12hrs)
</div>
</div>
| D02=
| D02= '''Medical Treatment'''<ref name="pmid18003962">{{cite journal| author=Jacobs DO| title=Clinical practice. Diverticulitis. | journal=N Engl J Med | year= 2007 | volume= 357 | issue= 20 | pages= 2057-66 | pmid=18003962 | doi=10.1056/NEJMcp073228 | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=18003962  }} </ref> <div style="float: left; text-align: left; padding:1em;"> Oral regimens <br>Intravenous regimen <br>
| D03= }}
❑[[Metronidazole]] (500mg / 6 - 8 hrs) + [[Quinolone]] (e.g. [[Ciprofloxacin]] 400mg / 12hrs) <br>
❑[[Metronidazole]] (500mg / 6 - 8 hrs) + [[Cephalosporin#Third generation|Third-generation cephalosporin]] (e.g. [[Ceftriaxone]] 1 - 2g / 12hrs)
❑[[Beta-lactam]] with [[Beta-lactamase]] inhibitor (e.g. [[Ampicillin sulbactam]] 3g / 6hrs)</div>
| D03= Stage the severity by using:<div style="float: left; text-align: left; padding:1em;">
❑ [[Diverticulitis resident survival guide#European Association for Endoscopic Surgery clinical Classification|European Association for Endoscopic Surgery clinical Classification]] <br>
❑ [[Diverticulitis resident survival guide#Buckley Classification|Buckley Classification]] </div>}}
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{{familytree | | | | |,|-|^|-|.| | | |,|-|-|-|-|-|+|-|-|-|-|.| | | | | | }}
{{familytree | | | | E01 | | E02 | | E03 | | | | E04 | | | E05 | | | | | E01= | E02= | E03= | E04= | E05=}}
{{familytree | | | | E01 | | E02 | | E03 | | | | E04 | | | E05 | | | | | E01= | E02= | E03= | E04= | E05=}}
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====Buckley Classification====
====Buckley Classification<ref name="pmid18479497">{{cite journal| author=Sheth AA, Longo W, Floch MH| title=Diverticular disease and diverticulitis. | journal=Am J Gastroenterol | year= 2008 | volume= 103 | issue= 6 | pages= 1550-6 | pmid=18479497 | doi=10.1111/j.1572-0241.2008.01879.x | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=18479497  }} </ref>====


{| Class="wikitable"
{| Class="wikitable"

Revision as of 17:32, 21 February 2014

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Andrea Tamayo Soto [2]

Definition

Causes

Life Threatening Causes

Common Causes

Management

Diagnostic Approach

Shown below is an algorithm depicting the diagnostic approach to diverticulitis according to the American Society of Colon and Rectal Surgeons[1] and the American Journal of Gastroenterology[2]

Characterize the symptoms:[3]

Abdominal pain

❑ Lower left quadrant

❑ Abdominal or preirectal fullness
Fever
Leukocytosis
Nausea
Vomits
Fecaluria[1]
Pneumaturia

Pyuria
 
 
 
 
 
Obtain a detailed history:[4]

❑ Age
❑ Previous history of diverticular disease
❑ Previous episodes of diverticulitis
❑ Chronic Abdominal pain
❑ Previous history of abdominal surgery
❑ Dietary regime
❑ History of:

Irritable bowel syndrome
❑ Inflammatory bowel disease
Colitis[5]
Immunodeficiency[6]
 
 
 
 
 
Examine the patient:

❑ Ectoscopy:

❑ Obesity

❑ Measure the heart rate
❑ Measure the temperature
❑ Abdomen:

❑ Rigidty
❑ Tendernes
 
 
 
 
 
Order labs and tests:[3]

❑ CT
❑ Blood Count:

❑ Leukocytes

❑ Abdominal X-rays with soluble contrast

Urianalysis

Therapeutic Approach

Shown below is an algorithm depicting the therapeutic approach to diverticulitis according to the American Journal of Gastroenterology[2] and the American Society of Colon and Rectal Surgeons [1]

 
 
 
 
 
 
 
 
 
Initial Management
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
Uncomplicated
 
 
 
 
 
 
 
 
 
 
 
Complicated[7]
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
Outpatient
❑ Inmunocompetent patient
❑Tolerated oral intake
❑Single episode
❑Mild to moderate pain
 
Hospitalized
❑Unable to tolerate oral intake
❑Severe pain
❑Inmunocompromised patients
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
Medical Treatment[3]
Oral regimens

Metronidazole (500mg / 6 - 8 hrs) + Quinolone (e.g. Ciprofloxacin 500 - 700mg / 12hrs)
Metronidazole (500mg / 6 - 8 hrs) + Trimethoprim (160mg / 12 hrs) - Sulfamethoxazole (800mg / 12hrs)
Amoxicillin- clavulanate (875mg / 12hrs)

 
Medical Treatment[3]
Oral regimens
Intravenous regimen

Metronidazole (500mg / 6 - 8 hrs) + Quinolone (e.g. Ciprofloxacin 400mg / 12hrs)
Metronidazole (500mg / 6 - 8 hrs) + Third-generation cephalosporin (e.g. Ceftriaxone 1 - 2g / 12hrs)

Beta-lactam with Beta-lactamase inhibitor (e.g. Ampicillin sulbactam 3g / 6hrs)
 
 
 
 
 
 
 
 
 
Stage the severity by using:
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
{{{ I0}}}
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 

European Association for Endoscopic Surgery clinical Classification[8]

Grades Clinical Description
Grade I
  • symptomatic
  • uncomplicated disease
  • Fever
  • Abdominal pain
Grade II
  • recurrent
  • symptomatic disease
Recurrence of above
Grade III
  • complicated disease
  • Abscess
  • Hemorrhage
  • Fistula
  • Phelgmom
  • Perforation
  • Obstruction
  • Purulent and fecal peritonitis

Buckley Classification[2]

CT Findings
Mild
Bowel wall thickening
Moderate
  • Bowel wall thickening > 3mm
  • Phelgmon or small abscess
Severe
  • Bowel wall thickening > 5mm
  • Perforation with subdiaphragmatic free air
  • Abscess > 5mm

Hinchey's Classification [3]

Stages CT Findings
Stage 1
  • small confined precolic or mesenteric abscess
Stage 2
  • Large abscess confined to the pelvis
Stage 3
  • Perforated diverticulitis
  • Peridiverticular abscess has ruptured
Stage 4
  • Free rupture of diverticula into the peritoneal cavity

Do´s

Don'ts

References

  1. 1.0 1.1 1.2 Feingold D, Steele SR, Lee S, Kaiser A, Boushey R, Buie WD; et al. (2014). "Practice parameters for the treatment of sigmoid diverticulitis". Dis Colon Rectum. 57 (3): 284–94. doi:10.1097/DCR.0000000000000075. PMID 24509449.
  2. 2.0 2.1 2.2 Sheth AA, Longo W, Floch MH (2008). "Diverticular disease and diverticulitis". Am J Gastroenterol. 103 (6): 1550–6. doi:10.1111/j.1572-0241.2008.01879.x. PMID 18479497.
  3. 3.0 3.1 3.2 3.3 3.4 Jacobs DO (2007). "Clinical practice. Diverticulitis". N Engl J Med. 357 (20): 2057–66. doi:10.1056/NEJMcp073228. PMID 18003962.
  4. Andeweg CS, Knobben L, Hendriks JC, Bleichrodt RP, van Goor H (2011). "How to diagnose acute left-sided colonic diverticulitis: proposal for a clinical scoring system". Ann Surg. 253 (5): 940–6. doi:10.1097/SLA.0b013e3182113614. PMID 21346548.
  5. Lamps LW, Knapple WL (2007). "Diverticular disease-associated segmental colitis". Clin Gastroenterol Hepatol. 5 (1): 27–31. doi:10.1016/j.cgh.2006.10.024. PMID 17234553.
  6. Tyau ES, Prystowsky JB, Joehl RJ, Nahrwold DL (1991). "Acute diverticulitis. A complicated problem in the immunocompromised patient". Arch Surg. 126 (7): 855–8, discussion 858-9. PMID 1854245.
  7. Floch MH (2006). "A hypothesis: is diverticulitis a type of inflammatory bowel disease?". J Clin Gastroenterol. 40 Suppl 3: S121–5. doi:10.1097/01.mcg.0000225502.29498.ba. PMID 16885694.
  8. Köhler L, Sauerland S, Neugebauer E (1999). "Diagnosis and treatment of diverticular disease: results of a consensus development conference. The Scientific Committee of the European Association for Endoscopic Surgery". Surg Endosc. 13 (4): 430–6. PMID 10094765.


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