INTUNIV drug interactions: Difference between revisions

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(Created page with "__NOTOC__ {{Guanfacine}} {{CMG}}; {{AE}} {{SS}} ==Drug Interactions== Guanfacine is primarily metabolized by CYP3A4 and its plasma concentrations can be affected significant...")
 
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{{Guanfacine}}
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==Drug Interactions==
 
Guanfacine is primarily metabolized by CYP3A4 and its plasma concentrations can be affected significantly by CYP3A4 inhibitors or inducers (Figure 1). Dose adjustments are recommended [see Dosage and Administration (2.7)]. Guanfacine does not significantly affect exposures of methylphenidate and lisdexamfetamine when coadministered (Figure 2). Therefore, no dose adjustments in methylphenidate or lisdexamfetamine are necessary.
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|}<ref name="dailymed.nlm.nih.gov">{{Cite web  | last =  | first =  | title = INTUNIV (GUANFACINE) TABLET, EXTENDED RELEASE INTUNIV (GUANFACINE) KIT [SHIRE US MANUFACTURING INC.] | url = http://dailymed.nlm.nih.gov/dailymed/lookup.cfm?setid=b972af81-3a37-40be-9fe1-3ddf59852528#section-12.1 | publisher =  | date =  | accessdate = 25 February 2014 }}</ref>
 
 
 
==References==
{{reflist|2}}
 
{{Antihypertensives and diuretics}}
{{Antihyperkinetics}}
{{Adrenergics}}
 
[[Category:Antihypertensive agents]]
[[Category:Guanidines]]
[[Category:Alpha-adrenergic agonists]]
[[Category:Acetamides]]
[[Category:Organochlorides]]
[[Category:Cardiovascular Drugs]]
[[Category:Drugs]]

Latest revision as of 03:55, 22 July 2014