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| __NOTOC__
| | #REDIRECT [[Acetazolamide#Drug Interactions]] |
| {{Acetazolamide}}
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| {{CMG}}; {{AE}} {{SS}}
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| ==Drug Interactions==
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| ===Aspirin - See WARNINGS===
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| DIAMOX modifies phenytoin metabolism with increased serum levels of [[phenytoin]]. This may increase or enhance the occurrence of [[osteomalacia]] in some patients receiving chronic phenytoin therapy. Caution is advised in patients receiving chronic concomitant therapy. By decreasing the gastrointestinal absorption of primidone, DIAMOX may decrease serum concentrations of [[primidone]] and its metabolites, with a consequent possible decrease in anticonvulsant effect. Caution is advised when beginning, discontinuing, or changing the dose of DIAMOX in patients receiving [[primidone]].
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| Because of possible additive effects with other carbonic anhydrase inhibitors, concomitant use is not advisable.
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| Acetazolamide may increase the effects of other folic acid antagonists.
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| Acetazolamide decreases urinary excretion of amphetamine and may enhance the magnitude and duration of their effect.
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| Acetazolamide reduces urinary excretion of [[quinidine]] and may enhance its effect. | |
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| Acetazolamide may prevent the urinary antiseptic effect of [[methenamine]]. Acetazolamide increases [[lithium]] excretion and the [[lithium]] may be decreased.
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| Acetazolamide and sodium bicarbonate used concurrently increase the risk of renal calculus formation.
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| Acetazolamide may elevate [[cyclosporine]] levels.
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| ===Drug/laboratory test interactions===
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| [[Sulfonamides]] may give false negative or decreased values for urinary phenolsulfonphthalein and phenol red elimination values for urinary protein, serum non-protein, and serum uric acid. Acetazolamide may produce an increased level of crystals in the urine.
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| Acetazolamide interferes with the HPLC method of assay for [[theophylline]]. Interference with the [[theophylline]] assay by [[acetazolamide]] depends on the solvent used in the extraction; acetazolamide may not interfere with other assay methods for [[theophylline]].<ref name="dailymed.nlm.nih.gov">{{Cite web | last = | first = | title = DIAMOX SEQUELS (ACETAZOLAMIDE) CAPSULE, EXTENDED RELEASE [DURAMED PHARMACEUTICALS, INC.] | url = http://dailymed.nlm.nih.gov/dailymed/lookup.cfm?setid=74e47451-2bc8-496e-88ad-c10002ee8e22 | publisher = | date = | accessdate = 25 February 2014 }}</ref>
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| ==References==
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| {{reflist|2}}
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| {{Anticonvulsants}}
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| {{Antiglaucoma preparations and miotics}}
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| {{Diuretics}}
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| [[Category:Carbonic anhydrase inhibitors]]
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| [[Category:Mountaineering and health]]
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| [[Category:Anticonvulsants]]
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| [[Category:Sulfonamides]]
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| [[Category:World Health Organization essential medicines]]
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| [[Category:Thiadiazoles]]
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| [[Category:Amides]]
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| [[Category:Cardiovascular Drugs]]
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| [[Category:Drugs]]
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