Magnesium sulfate overdosage: Difference between revisions

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__NOTOC__
#REDIRECT [[Magnesium sulfate#Overdosage]]
{{Magnesium sulfate}}
{{CMG}}; {{AE}} {{AZ}}
 
==Overdosage==
 
Magnesium intoxication is manifested by a sharp drop in blood pressure and respiratory paralysis. Disappearance of the patellar reflex is a useful clinical sign to detect the onset of magnesium intoxication. In the event of overdosage [[artificial ventilatio]]n must be provided until a calcium salt can be injected intravenously to antagonize the effects of magnesium.
 
For Treatment of Overdose
 
Artificial respiration is often required. Intravenous calcium, 10 to 20 mL of a 5% solution (diluted if desirable with isotonic sodium chloride for injection) is used to counteract effects of [[hypermagnesemia]]. Subcutaneous [[physostigmine]], 0.5 to 1 mg may be helpful.
 
[[Hypermagnesemia]] in the newborn may require resuscitation and assisted ventilation via endotracheal intubation or intermittent positive pressure ventilation as well as intravenous calcium.<ref name="dailymed.nlm.nih.gov">{{Cite web  | last =  | first =  | title = MAGNESIUM SULFATE (MAGNESIUM SULFATE HEPTAHYDRATE) INJECTION, SOLUTION [PHYSICIANS TOTAL CARE, INC.] | url = http://dailymed.nlm.nih.gov/dailymed/lookup.cfm?setid=70f46528-7a1c-48e7-9f0f-7e920e708d63 | publisher =  | date =  | accessdate = }}</ref>
 
==References==
{{Reflist}}
 
{{FDA}}
 
[[Category:Drugs]]

Latest revision as of 21:48, 21 July 2014