Torsemide (tablet): Difference between revisions

Torsemide (tablet)
Clinical data
AHFS/Drugs.com	International Drug Names
MedlinePlus	a601212
Pregnancy; category	US: C (Risk not ruled out) ; ;
Routes of; administration	Oral, IV
ATC code	C03CA04 (WHO) ;
Legal status
Legal status	US: ℞-only ;
Pharmacokinetic data
Bioavailability	80-90%
Protein binding	Highly bound (>99%).
Metabolism	Hepatic (80%)
Elimination half-life	3.5 hours; Cirrhosis: 7-8 hours
Identifiers
	IUPAC name N-[(isopropylamino)carbonyl]-4-[(3-methylphenyl)amino]pyridine-3-sulfonamide;
CAS Number	56211-40-6;
PubChem CID	41781;
DrugBank	DB00214 ;
ChemSpider	38123 ;
UNII	W31X2H97FB;
KEGG	D00382 ;
ChEMBL	ChEMBL1148 ;
E number	{{#property:P628}}
ECHA InfoCard	{{#property:P2566}}Lua error in Module:EditAtWikidata at line 36: attempt to index field 'wikibase' (a nil value).
Chemical and physical data
Formula	C16H20N4O3S
Molar mass	348.421 g/mol
3D model (JSmol)	Interactive image;
	SMILES O=S(=O)(c2c(Nc1cc(ccc1)C)ccnc2)NC(=O)NC(C)C;
	InChI InChI=1S/C16H20N4O3S/c1-11(2)18-16(21)20-24(22,23)15-10-17-8-7-14(15)19-13-6-4-5-12(3)9-13/h4-11H,1-3H3,(H,17,19)(H2,18,20,21) ; Key:NGBFQHCMQULJNZ-UHFFFAOYSA-N ;
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VisualWikitext

Revision as of 19:36, 19 March 2014

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Synonyms / Brand Names: DEMADEX^®; generic

Overview

Torsemide is a diuretic of the pyridine-sulfonylurea class used in treatment of edema associated with congestive heart failure, renal disease, or hepatic disease.

Prescribing Information

Demadex (torsemide) tablet

TORSEMIDE tablet

TORSEMIDE injection, solution

References

Template:Diuretic Catogory:Drugs

@@ Line 1: / Line 1: @@
-{{Metoprolol}}__NOEDITSECTION____NOTOC__
+{{Torsemide}}__NOEDITSECTION____NOTOC__
 {{CMG}}
@@ Line 7: / Line 7: @@
 ==Overview==
-Metoprolol is a selective [[beta blocker|β<sub>1</sub> receptor blocker]] used in treatment of several diseases of the [[cardiovascular system]], especially [[hypertension]]. The active substance metoprolol is employed either as ''metoprolol [[succinic acid|succinate]]'' or as ''metoprolol [[tartrate]]'' (where 100 mg metoprolol [[tartrate]] corresponds to 95 mg metoprolol [[succinic acid|succinate]]). The [[tartrate]] is an immediate-release and the [[succinic acid|succinate]] is an extended-release [[Pharmaceutical formulation|formulation]].<ref>{{cite journal | author = Cupp M | title = Alternatives for Metoprolol Succinate | journal = Pharmacist's Letter / Prescriber's Letter | year = 2009 | volume = 25 | issue = 250302 | url = http://www.ncbop.org/PDF/MetoprololShortageMarch2009.pdf | format = pdf | accessdate = }}</ref>
+Torsemide is a diuretic of the pyridine-sulfonylurea class used in treatment of [[edema]] associated with [[congestive heart failure]], [[renal disease]], or hepatic disease.
 ==Category==
-Antianginals, antiarrhythmic agents, antihypertensive agents, antimigraine drugs, beta blockers, cardiovascular drugs
+Loop Diuretic
 ==Prescribing Information==
-===[[Lopressor|Lopressor (metoprolol tartrate) tablet]]===
+===[[Demadex|Demadex (torsemide) tablet]]===
-===[[Toprol XL|Toprol XL (metoprolol succinate) tablet, extended release]]===
+===[[TORSEMIDE|TORSEMIDE tablet]]===
+===[[TORSEMIDE|TORSEMIDE injection, solution ]]===
 ==References==
@@ Line 23: / Line 25: @@
 {{reflist|2}}
-{{beta blockers}}
+{{diuretic}}
-[[Category:Antianginals]]
-[[Category:Antiarrhythmic agents]]
-[[Category:Antihypertensive agents]]
-[[Category:Antimigraine drugs]]
-[[Category:Beta blockers]]
 [[Category:Cardiovascular Drugs]]
+[[Catogory:Drugs]]