Metoprolol: Difference between revisions
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====Lopressor HCT (metoprolol tartrate and hydrochlorothiazide) tablet==== | ====Lopressor HCT (metoprolol tartrate and hydrochlorothiazide) tablet==== | ||
====Metoprolol (metoprolol tartrate) injection==== | ====Metoprolol (metoprolol tartrate) injection==== | ||
====Metoprolol succinate (metoprolol succinate) tablet, film coated, extended release==== | ====Metoprolol succinate (metoprolol succinate) tablet, film coated, extended release==== | ||
====Metoprolol succinate tablet, extended release==== | ====Metoprolol succinate tablet, extended release==== |
Revision as of 13:31, 20 March 2014
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Clinical data | |
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Trade names | Lopressor, Toprol-xl |
AHFS/Drugs.com | Monograph |
MedlinePlus | a682864 |
[[Regulation of therapeutic goods |Template:Engvar data]] |
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Pregnancy category | |
Routes of administration | Oral, IV |
ATC code | |
Legal status | |
Legal status |
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Pharmacokinetic data | |
Bioavailability | 12% |
Metabolism | Hepatic via CYP2D6, CYP3A4 |
Elimination half-life | 3-7 hours |
Excretion | Renal |
Identifiers | |
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CAS Number | |
PubChem CID | |
IUPHAR/BPS | |
DrugBank | |
ChemSpider | |
UNII | |
KEGG | |
ChEBI | |
ChEMBL | |
E number | {{#property:P628}} |
ECHA InfoCard | {{#property:P2566}}Lua error in Module:EditAtWikidata at line 36: attempt to index field 'wikibase' (a nil value). |
Chemical and physical data | |
Formula | C15H25NO3 |
Molar mass | 267.364 g/mol |
3D model (JSmol) | |
Melting point | 120 °C (248 °F) |
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Synonyms / Brand Names: Lopressor, Toprol XL
Overview
Metoprolol is a competitive, β1-selective (cardioselective) blocker used in treatment of angina pectoris, hypertension, arrhythmia, and migraine. Common adverse reactions include bradyarrhythmia, heart block, heart failure, hypotension, pruritus, rash, constipation, diarrhea, indigestion, nausea, dizziness, fatigue, headache, depression, dyspnea, and wheezing.
The active substance metoprolol is employed either as metoprolol succinate or as metoprolol tartrate (where 100 mg metoprolol tartrate corresponds to 95 mg metoprolol succinate). The tartrate is an immediate-release and the succinate is an extended-release formulation.[1]
Category
Anti-anginal, antiarrhythmic, beta-adrenergic blocker
Prescribing Information
Dutoprol (metoprolol succinate and hydrochlorothiazide) tablet, film coated
Hypertensolol (metoprolol tartrate, arginine) kit
Lopressor (metoprolol tartrate) injection, solution
Lopressor (metoprolol tartrate) tablet
Lopressor HCT (metoprolol tartrate and hydrochlorothiazide) tablet
Metoprolol (metoprolol tartrate) injection
Metoprolol succinate (metoprolol succinate) tablet, film coated, extended release
Metoprolol succinate tablet, extended release
Metoprolol succinate tablet, film coated, extended release
Metoprolol tartrate (metoprolol tartrate) injection
Metoprolol tartrate (metoprolol tartrate) tablet, film coated
Metoprolol tartrate (metoprolol tartrate) tablet
Metoprolol tartrate (metoprolol tartrate) tablet, film coated
Metoprolol tartrate (metoroprolol tartrate) injection, solution
Metoprolol tartrate and hydrochlorothiazide 100 mg-25 mg (metoprolol tartrate and hydrochlorothiazide) tablet
Metoprolol tartrate and hydrochlorothiazide 100 mg-50 mg (metoprolol tartrate and hydrochlorothiazide) tablet
Metoprolol tartrate and hydrochlorothiazide 50 mg-25 mg (metoprolol tartrate and hydrochlorothiazide) tablet
Metoprolol tartrate and hydrochlorothiazide tablet
Metoprolol tartrate injection, solution
Metoprolol tartrate tablet
Metoprolol tartrate tablet, film coated
Toprol XL (metoprolol succinate) tablet, extended release
Toprolxl XL (metoprolol succinate) tablet, extended release
References
- ↑ Cupp M (2009). "Alternatives for Metoprolol Succinate" (pdf). Pharmacist's Letter / Prescriber's Letter. 25 (250302).
- Pages with script errors
- Template:drugs.com link with non-standard subpage
- Drugs with non-standard legal status
- E number from Wikidata
- ECHA InfoCard ID from Wikidata
- Chemical articles with unknown parameter in Infobox drug
- Infobox drug articles with non-default infobox title
- Antianginals
- Antiarrhythmic agents
- Antihypertensive agents
- Antimigraine drugs
- Beta blockers
- Cardiovascular Drugs