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===''[[Spironolactone|Spironolactone]]''===
===''[[Spironolactone|Spironolactone]]''===


* [[Toprol XL]]
* [[Aldactone]]
* [[Toprolxl XL]]


===''[[Spironolactone/Hydrochlorothiazide|Spironolactone/Hydrochlorothiazide]]''===
===''[[Spironolactone/Hydrochlorothiazide|Spironolactone/Hydrochlorothiazide]]''===

Revision as of 17:33, 11 April 2014

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Spironolactone

Spironolactone/Hydrochlorothiazide

Overview

Spironolactone is a competitive, β1-selective (cardioselective) blocker used in treatment of angina pectoris, hypertension, arrhythmia, and migraine. Common adverse reactions include bradyarrhythmia, heart block, heart failure, hypotension, pruritus, rash, constipation, diarrhea, indigestion, nausea, dizziness, fatigue, headache, depression, dyspnea, and wheezing.

The active substance metoprolol is employed either as metoprolol succinate or as metoprolol tartrate. The tartrate is an immediate-release and the succinate is an extended-release formulation.

Category

Aldosterone Antagonist