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| ==SAMPLE==
| | __NOTOC__ |
| | {{Gemfibrozil}} |
| | {{CMG}}; {{AE}} {{SS}} |
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| <SMALL><font color="#FF4C4C">'''▸ Click on the following categories to expand treatment regimens.'''</font></SMALL>
| | '''''For patient information about Gemfibrozil, click [[Gemfibrozil (patient information)|here]].''''' |
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| {| | | {{SB}} LOPID<sup>®</sup>,generic |
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| <div style="border-radius: 5px 5px 0 0; border: solid 1px #20538D; border-bottom: 0px; text-shadow: 0 -1px 0 rgba(0, 0, 0, 0.5); box-shadow: inset 0 1px 1px rgba(255, 255, 255, 0.5), 0 1px 1px rgba(0, 0, 0, 0.5); height: 30px; line-height: 30px; width: 225px; background: #A1BCDD; text-align: center;"> | |
| <font color="#FFF">
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| '''Title'''
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| </font> | |
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| <div class="mw-customtoggle-table98" style="cursor: pointer; border-radius: 0 0 0 0; border: solid 1px #20538D; text-shadow: 0 -1px 0 rgba(0, 0, 0, 0.5); box-shadow: inset 0 1px 1px rgba(255, 255, 255, 0.5), 0 1px 1px rgba(0, 0, 0, 0.5); height: 30px; line-height: 30px; width: 225px; background: #4479BA;">
| | ==Overview== |
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| ▸ '''Subtitle'''
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| </div>
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| <div class="mw-customtoggle-table99" style="cursor: pointer; border-radius: 0 0 0 0; border: solid 1px #20538D; text-shadow: 0 -1px 0 rgba(0, 0, 0, 0.5); box-shadow: inset 0 1px 1px rgba(255, 255, 255, 0.5), 0 1px 1px rgba(0, 0, 0, 0.5); height: 30px; line-height: 30px; width: 225px; background: #4479BA;">
| | '''Gemfibrozil''' is the [[International Nonproprietary Name|generic name]] for an oral drug used to lower [[lipid]] levels. It belongs to a group of drugs known as [[fibrates]]. It is most commonly sold as the brand name, '''Lopid'''. |
| <font color="#FFF">
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| ▸ '''Subtitle'''
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| </font>
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| </div>
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| | ==Category== |
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| | Cardiovascular Drug,Phenol ethers,Fibrates,Lipid modifying agents |
| {| class="mw-collapsible mw-collapsed" id="mw-customcollapsible-table98" style="background: #FFFFFF;"
| | ==FDA Package Insert== |
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| ! style="height: 30px; line-height: 30px; background: #4479BA; border: 0px; font-size: 100%; text-shadow: 0 -1px 0 rgba(0, 0, 0, 0.5);" align=center | {{fontcolor|#FFF|Table 1}}
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| ! style="height: 30px; line-height: 30px; background: #4479BA; border: 0px; font-size: 100%; text-shadow: 0 -1px 0 rgba(0, 0, 0, 0.5);" align=center | {{fontcolor|#FFF|Table 2}}
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| | ''' [[Gemfibrozil indications and usage|Indications and Usage]]''' |
| | '''| [[Gemfibrozil dosage and administration|Dosage and Administration]]''' |
| | '''| [[Gemfibrozil contraindications|Contraindications]]''' |
| | '''| [[Gemfibrozil warnings and precautions|Warnings and Precautions]]''' |
| | '''| [[Gemfibrozil adverse reactions|Adverse Reactions]]''' |
| | '''| [[Gemfibrozil drug interactions|Drug Interactions]]''' |
| | '''| [[Gemfibrozil use in specific populations|Use in Specific Populations]]''' |
| | '''| [[Gemfibrozil overdosage|Overdosage]]''' |
| | '''| [[Gemfibrozil description|Description]]''' |
| | '''| [[Gemfibrozil clinical pharmacology|Clinical Pharmacology]]''' |
| | '''| [[Gemfibrozil nonclinical toxicology|Nonclinical Toxicology]]''' |
| | '''| [[Gemfibrozil how supplied storage and handling|How Supplied/Storage and Handling]]''' |
| | '''| [[Gemfibrozil labels and packages|Labels and Packages]]''' |
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| ==Empiric Therapy== | | ==Mechanism of Action== |
| <SMALL><font color="#FF4C4C">'''▸ Click on the following categories to expand treatment regimens.'''</font></SMALL>
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| {|
| | The mechanism of action of gemfibrozil has not been definitely established. In man, LOPID has been shown to inhibit peripheral lipolysis and to decrease the hepatic extraction of free fatty acids, thus reducing hepatic [[triglyceride]] production. LOPID inhibits synthesis and increases clearance of VLDL carrier [[apolipoprotein B]], leading to a decrease in [[VLDL]] production. |
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| <div style="border-radius: 5px 5px 0 0; border: solid 1px #20538D; border-bottom: 0px; text-shadow: 0 -1px 0 rgba(0, 0, 0, 0.5); box-shadow: inset 0 1px 1px rgba(255, 255, 255, 0.5), 0 1px 1px rgba(0, 0, 0, 0.5); height: 30px; line-height: 30px; width: 350px; background: #A1BCDD; text-align: center;">
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| '''Empiric Therapy'''
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| | ==References== |
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| '''Community-acquired Pneumonia '''
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| <div class="mw-customtoggle-table01" style="cursor: pointer; border-radius: 0 0 0 0; border: solid 1px #20538D; text-shadow: 0 -1px 0 rgba(0, 0, 0, 0.5); box-shadow: inset 0 1px 1px rgba(255, 255, 255, 0.5), 0 1px 1px rgba(0, 0, 0, 0.5); height: 30px; line-height: 30px; width: 350px; background: #4479BA;">
| | {{Reflist|2}} |
| <font color="#FFF">
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| ▸ '''Outpatient'''
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| </font>
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| <div class="mw-customtoggle-table02" style="cursor: pointer; border-radius: 0 0 0 0; border: solid 1px #20538D; text-shadow: 0 -1px 0 rgba(0, 0, 0, 0.5); box-shadow: inset 0 1px 1px rgba(255, 255, 255, 0.5), 0 1px 1px rgba(0, 0, 0, 0.5); height: 30px; line-height: 30px; width: 350px; background: #4479BA;">
| | {{Lipid modifying agents}} |
| <font color="#FFF">
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| ▸ '''Non-ICU Inpatient'''
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| </font>
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| <div class="mw-customtoggle-table03" style="cursor: pointer; border-radius: 0 0 0 0; border: solid 1px #20538D; text-shadow: 0 -1px 0 rgba(0, 0, 0, 0.5); box-shadow: inset 0 1px 1px rgba(255, 255, 255, 0.5), 0 1px 1px rgba(0, 0, 0, 0.5); height: 30px; line-height: 30px; width: 350px; background: #4479BA;">
| | [[Category:Fibrates]] |
| <font color="#FFF">
| | [[Category:Phenol ethers]] |
| ▸ '''ICU Inpatient'''
| | [[Category:Cardiovascular Drug]] |
| </font>
| | [[Category:Drug]] |
| </div>
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| <div class="mw-customtoggle-table04" style="cursor: pointer; border-radius: 0 0 0 0; border: solid 1px #20538D; text-shadow: 0 -1px 0 rgba(0, 0, 0, 0.5); box-shadow: inset 0 1px 1px rgba(255, 255, 255, 0.5), 0 1px 1px rgba(0, 0, 0, 0.5); height: 30px; line-height: 30px; width: 350px; background: #4479BA;">
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| <font color="#FFF">
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| ▸ '''Special Situations'''
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| </font>
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| </div>
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| <div style="border-radius: 0 0 0 0; border: solid 1px #20538D; border-bottom: 0px; text-shadow: 0 -1px 0 rgba(0, 0, 0, 0.5); box-shadow: inset 0 1px 1px rgba(255, 255, 255, 0.5), 0 1px 1px rgba(0, 0, 0, 0.5); height: 30px; line-height: 30px; width: 350px; background: #A1BCDD; text-align: center;">
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| <font color="#FFF">
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| '''Hospital-acquired and Healthcare-acquired Pneumonia '''
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| </font>
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| </div>
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| <div class="mw-customtoggle-table05" style="cursor: pointer; border-radius: 0 0 0 0; border: solid 1px #20538D; text-shadow: 0 -1px 0 rgba(0, 0, 0, 0.5); box-shadow: inset 0 1px 1px rgba(255, 255, 255, 0.5), 0 1px 1px rgba(0, 0, 0, 0.5); height: 30px; line-height: 30px; width: 350px; background: #4479BA;">
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| <font color="#FFF">
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| ▸ '''Early Onset'''
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| </font>
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| <div class="mw-customtoggle-table06" style="cursor: pointer; border-radius: 0 0 5px 5px; border: solid 1px #20538D; text-shadow: 0 -1px 0 rgba(0, 0, 0, 0.5); box-shadow: inset 0 1px 1px rgba(255, 255, 255, 0.5), 0 1px 1px rgba(0, 0, 0, 0.5); height: 30px; line-height: 30px; width: 350px; background: #4479BA;">
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| ▸ '''Late Onset'''
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