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| {{drugbox
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| | image = Alfentanil.png
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| | IUPAC_name = ''N''-[1-[2-(4-ethyl-5-oxo-1,4-dihydrotetrazol-1-yl)ethyl]-<br />4-(methoxymethyl)-4-piperidyl]-''N''-phenyl-propanamide
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| | CAS_number = 71195-58-9
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| | ATC_prefix = N01
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| | ATC_suffix = AH02
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| | PubChem = 189496
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| | DrugBank = APRD00726
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| | C = 21 | H = 32 | N = 6 | O = 3
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| | molecular_weight = 416.517 g/mol
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| | melting_point = 140.8
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| | bioavailability = Not applicable
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| | protein_bound = 92%
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| | metabolism = [[Liver|Hepatic]]
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| | elimination_half-life = 90–111 minutes
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| | legal_US = Schedule II
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| | routes_of_administration = [[Intravenous therapy|Intravenous]]
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| }}
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| '''Alfentanil''' (trade name '''Alfenta''') is a potent but short-acting synthetic [[opioid]] [[analgesic]] [[medication|drug]], used for [[anaesthesia]] in [[surgery]]. It is an analogue of fentanyl with 10-20% the potency of fentanyl. It is an OP3 mu-agonist.
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| While alfentanil tends to cause less [[cardiovascular]] complications than other similar drugs such as [[fentanyl]] and [[remifentanil]] it tends to give stronger [[respiratory depression]] and so requires careful monitoring of breathing and vital signs. Alfentanil is administered by the [[parenteral]] (injected) route for fast onset of effects and precise control of dosage.
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| Alfentanil is a restricted drug which is classified as [[Schedule II]] in the USA, according to the [[Drug Enforcement Agency|U.S. DEA]] website.<ref name="http://www.deadiversion.usdoj.gov/schedules/listby_sched/sched2.htm">[http://www.deadiversion.usdoj.gov/schedules/listby_sched/sched2.htm From DEA website, accessed 23 Jan 2007]</ref>
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| Alfentanil was discovered at [[Janssen Pharmaceutica]] in [[1976]].
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| ==References==
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| <div class="references-small">
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| <references/>
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| </div>
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| ==External links==
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| * [http://www.nlm.nih.gov/medlineplus/druginfo/medmaster/a601130.html some more info]
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| {{Analgesics}}
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| {{General anesthetics}}
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| [[de:Alfentanil]]
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| [[fr:Alfentanil]]
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| [[pt:Alfentanil]]
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| [[sv:Alfentanil]]
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| [[th:อัลเฟนทานิล]]
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| [[Category:Drugs]]
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