Lithium carbonate: Difference between revisions

Revision as of 20:05, 26 May 2014

{{DrugProjectFormSinglePage |authorTag=Pratik Bahekar, MBBS [1] |genericName=Lithium carbonate |aOrAn=a |drugClass=mood Stabilizer |indication=bipolar disorder, maintenance therapy and manic episode |adverseReactions=acne, hypothyroidism, weight increased, gastritis, nausea, xerostomia, leukocytosis, fine tremor, hyperreflexia, deep tendon, nephrotoxicity, polyuria, increased thirst. |blackBoxWarningTitle=TITLE |blackBoxWarningBody=Condition Name: (Content) |fdaLIADAdult=*Bipolar disorder, maintenance therapy

Maintenance 900 to 1200 mg/day PO in 2 to 3 divided doses

Bipolar disorder, manic episode

1800 mg/day PO in 2 to 3 divided doses

|offLabelAdultGuideSupport=There is limited information about Off-Label Guideline-Supported Use of Lithium carbonate in adult patients. |offLabelAdultNoGuideSupport=There is limited information about Off-Label Non–Guideline-Supported Use of Lithium carbonate in adult patients. |fdaLIADPed=*Safety below the age of 12 have not been established. B*ipolar disorder, maintenance therapy

12 yr and older, extended-release tablets, maintenance, 900 to 1200 mg/day ORALLY in 2 to 3 divided doses; desired serum lithium levels ranging between 0.6 to 1.2 mEq/L

Bipolar disorder, maintenance therapy

Immediate-release tablet and capsule formulations, maintenance, 300 mg PO 3 to 4 times daily

Bipolar disorder, manic episode

12 yr and older, extended-release tablets, acute mania, 1800 mg/day PO in 2 to 3 divided doses

|offLabelPedGuideSupport=There is limited information about Off-Label Guideline-Supported Use of Lithium carbonate in pediatric patients. |offLabelPedNoGuideSupport=There is limited information about Off-Label Non–Guideline-Supported Use of Lithium carbonate in pediatric patients. |drugBox=

Template:Chembox header2 \| Lithium carbonate
Identifiers
CAS Number	554-13-2^Y
3D model (JSmol)	Interactive image
ChEBI	CHEBI:6504^Y
ChEMBL	ChEMBL1200826^N
ChemSpider	10654^Y
ECHA InfoCard	Lua error in Module:Wikidata at line 879: attempt to index field 'wikibase' (a nil value). Lua error in Module:Wikidata at line 879: attempt to index field 'wikibase' (a nil value).
KEGG	D00801^Y
PubChem CID	11125
UNII	2BMD2GNA4V^Y
InChI InChI=1S/CH2O3.2Li/c2-1(3)4;;/h(H2,2,3,4);;/q;2+1/p-2^Y Key: XGZVUEUWXADBQD-UHFFFAOYSA-L^Y InChI=1/CH2O3.2Li/c2-1(3)4;;/h(H2,2,3,4);;/q;2+1/p-2 Key: XGZVUEUWXADBQD-NUQVWONBAY
SMILES [Li+].[Li+].[O-]C([O-])=O
Properties
Chemical formula	CLi₂O₃
Molar mass	73.89 g·mol⁻¹
Template:Chembox header2 \| Except where noted otherwise, data are given for materials in their standard state (at 25 °C, 100 kPa) Infobox disclaimer and references

↑ Pradyot Patnaik. Handbook of Inorganic Chemicals. McGraw-Hill, 2002, ISBN 0-07-049439-8

[1] Pradyot Patnaik. Handbook of Inorganic Chemicals. McGraw-Hill, 2002, ISBN 0-07-049439-8

@@ Line 23: / Line 23: @@
 |offLabelPedGuideSupport=There is limited information about <i>Off-Label Guideline-Supported Use</i> of Lithium carbonate in pediatric patients.
 |offLabelPedNoGuideSupport=There is limited information about <i>Off-Label Non–Guideline-Supported Use</i> of Lithium carbonate in pediatric patients.
+|drugBox={{chembox2
+| Verifiedfields = changed
+| Watchedfields = changed
+| verifiedrevid = 476992822
+| Name = Lithium carbonate
+| ImageFile = 225px-Lithium carbonate.jpg
+| ImageSize = 225px
+| ImageName = Lithium carbonate
+| IUPACName = Lithium carbonate
+| OtherNames = Dilithium carbonate, Carbolith, Cibalith-S, Duralith, Eskalith, Lithane, Lithizine, Lithobid, Lithonate, Lithotabs Priadel, [[Zabuyelite]]
+| Section1 = {{Chembox Identifiers
+| ChemSpiderID_Ref = {{chemspidercite|correct|chemspider}}
+| ChemSpiderID = 10654
+| UNII_Ref = {{fdacite|correct|FDA}}
+| UNII = 2BMD2GNA4V
+| ChEMBL_Ref = {{ebicite|changed|EBI}}
+| ChEMBL = 1200826
+| InChI = 1/CH2O3.2Li/c2-1(3)4;;/h(H2,2,3,4);;/q;2*+1/p-2
+| InChIKey = XGZVUEUWXADBQD-NUQVWONBAY
+| ChEBI_Ref = {{ebicite|correct|EBI}}
+| ChEBI = 6504
+| SMILES = [Li+].[Li+].[O-]C([O-])=O
+| StdInChI_Ref = {{stdinchicite|correct|chemspider}}
+| StdInChI = 1S/CH2O3.2Li/c2-1(3)4;;/h(H2,2,3,4);;/q;2*+1/p-2
+| StdInChIKey_Ref = {{stdinchicite|correct|chemspider}}
+| StdInChIKey = XGZVUEUWXADBQD-UHFFFAOYSA-L
+| CASNo = 554-13-2
+| CASNo_Ref = {{cascite|correct|CAS}}
+| PubChem = 11125
+| RTECS = OJ5800000
+| KEGG_Ref = {{keggcite|correct|kegg}}
+| KEGG = D00801
+ }}
+| Section2 = {{Chembox Properties
+| Li=2|C=1|O=3
+| Appearance = Odorless white powder
+| Density = 2.11 g/cm<sup>3</sup>
+| MeltingPtC = 720-723
+| BoilingPtC = 1310
+| Boiling_notes = decomposes
+| Solubility = 1.54 g/100ml (0 °C)<br> 1.32 g/100ml (20 °C)<br> 1.27 g/100ml (25 °C)<br> 1.00 g/100ml (60 °C)<br> 0.72 g/100ml (100 °C)
+| SolubleOther = insoluble in [[acetone]], [[ammonia]] and [[ethanol]]
+| RefractIndex = 1.428 <ref>Pradyot Patnaik. ''Handbook of Inorganic Chemicals''. McGraw-Hill, 2002, ISBN 0-07-049439-8</ref>
+ }}
+| Section4 = {{Chembox Thermochemistry
+|   DeltaGf = -1132.4 kJ/mol<ref name=chemister>http://chemister.ru/Database/properties-en.php?dbid=1&id=608</ref>
+|   DeltaHf = -16.46 kJ/g<br> -1215.6 kJ/mol<ref name=chemister />
+|   DeltaHc =
+|   Entropy = 90.37 J/mol·K<ref name=chemister />
+|   HeatCapacity = 1.341 J/(g·K)<br> 97.4 J/mol·K<ref name=chemister />
+ }}
 |alcohol=Alcohol-Lithium carbonate interaction has not been established. Talk to your doctor about the effects of taking alcohol with this medication.
 }}

Lithium carbonate: Difference between revisions

Revision as of 20:05, 26 May 2014

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