Chikungunya history and symptoms: Difference between revisions

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Revision as of 18:59, 5 June 2014

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

The common symptoms of Chikungunya include fever, petechial or maculopapular rash and arthralgia or arthritis affecting multiple joints.

The majority of people infected with chikungunya virus become symptomatic.
The incubation period is typically 3–7 days (range, 1–12 days).
The disease is most often characterized by acute onset of fever (typically >39°C [102°F]) and polyarthralgia.
Joint symptoms are usually bilateral and symmetric, and can be severe and debilitating.
Other symptoms may include headache, myalgia, arthritis, conjunctivitis, nausea/vomiting, or maculopapular rash.
Acute symptoms typically resolve within 7–10 days.

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 * Joint symptoms are usually bilateral and symmetric, and can be severe and debilitating.
 * Other symptoms may include headache, myalgia, arthritis, conjunctivitis, nausea/vomiting, or maculopapular rash.
-* Clinical laboratory findings can include lymphopenia, thrombocytopenia, elevated creatinine, and elevated hepatic transaminases.
 * Acute symptoms typically resolve within 7–10 days.
-* Rare complications include uveitis, retinitis, myocarditis, hepatitis, nephritis, bullous skin lesions, hemorrhage, meningoencephalitis, myelitis, Guillain-Barré syndrome, and cranial nerve palsies.
-* Persons at risk for severe disease include neonates exposed intrapartum, older adults (e.g., > 65 years), and persons with underlying medical conditions (e.g., hypertension, diabetes, or cardiovascular disease).
-* Some patients might have relapse of rheumatologic symptoms (e.g., polyarthralgia, polyarthritis, tenosynovitis) in the months following acute illness.
-* Studies report variable proportions of patients with persistent joint pains for months to years.
-* Mortality is rare and occurs mostly in older adults.
 ==References==