Lymphadenopathy medical therapy

Lymphadenopathy Microchapters
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Raviteja Guddeti, M.B.B.S. [2]; Vendhan Ramanujam M.B.B.S [3]

Principles of Therapy

Medical management of lymphadenopathy depends on the underlying cause.

• Antibiotics, antivirals, antifungals and antiparasitic medications are prescribed for infections due to bacteria, virus, fungi and parasites respectively.
• Chemotherapy is instituted for those tumors that cannot be treated by surgery.
• Radiation therapy is used in refractory tumors and metastatic tumors.

Therapy Based on Clinical Form

Generalized Lymphadenitis

Pathogen Based Therapy

▸ Click on the following categories to expand treatment regimens.

Bacteria   ▸  Mycobacterium Tuberculosis   ▸  Brucella   ▸  Leptospira   ▸  Treponema pallidum   ▸  Burkholderia   ▸  Salmonella Typhi Chlamydia   ▸  Chlamydia Trachomatis Fungi   ▸  Histoplasma   ▸  Cryptococcus Neoformans Viral   ▸  Measles Virus   ▸  Rubella Virus   ▸  Epstein-Barr Virus   ▸  Cytomegalovirus   ▸  Herpes Simplex Virus   ▸  Human Immunodeficiency Virus Protozoans   ▸  Leishmania   ▸  Trypanosoma   ▸  Toxoplasma Gondii Helminths   ▸  Brugia Malayi   ▸  Wuchereria Bancrofti Regional Lymphadenitis Pathogen Based Therapy ▸ Click on the following categories to expand treatment regimens. Cervical Lymphadentitis - Bacteria   ▸  Group A Beta-Hemolytic Streptococci   ▸  Staphylococcus Aureus   ▸  Mycobacterium Tuberculosis   ▸  Mycobacterium Scrofulaceum   ▸  Mycobacterium Avium-Intracellulare   ▸  Bartonella Henselae   ▸  Francisella Tularensis Cervical Lymphadentitis - Protozoans   ▸  Toxoplasma gondii Axillary Lymphadentitis - Bacteria   ▸  Group A Beta-Hemolytic Streptococci   ▸  Staphylococcus Aureus   ▸  Bartonella Henselae   ▸  Francisella Tularensis   ▸  Yersinia Pestis Axillary Lymphadentitis - Fungi   ▸  Sporotrichosis Inguinal Lymphadentitis - Bacteria   ▸  Group A Beta-Hemolytic Streptococci   ▸  Staphylococcus Aureus   ▸  Bartonella Henselae   ▸  Francisella Tularensis   ▸  Yersinia Pestis   ▸  Treponema Pallidum   ▸  Haemophilus Ducreyi Inguinal Lymphadentitis - Chlamydia   ▸  Chlamydia Trachomatis Inguinal Lymphadentitis - Viral   ▸  Herpes Simplex Virus Lymphadentitis of Extremities - Bacteria   ▸  Francisella Tularensis   ▸  Mycobacterium Marinum   ▸  Mycobacterium Chelonae   ▸  Nocardia Brasiliensis Lymphadentitis of Extremities - Fungi   ▸  Sporotrichosis Lymphadentitis of Extremities - Protozoans   ▸  Leishmania Mycobacterium Tuberculosis Preferred Regimen Intensive Phase † ▸ Isoniazid 5 mg/kg PO qd OR ▸ Isoniazid 10 mg/kg PO 3 times per week PLUS ▸ Rifampicin 10 mg/kg PO qd OR ▸ Rifampicin 10 mg/kg PO 3 times per week PLUS ▸ Pyrazinamide 25 mg/kg PO qd OR ▸ Pyrazinamide 35 mg/kg PO 3 times per week PLUS ▸ Ethambutol 14.5-21.1 mg/kg PO qd OR ▸ Ethambutol 36.4-52.6 mg/kg PO 3 times per week' Continuation Phase †† ▸ Isoniazid 5 mg/kg PO qd OR ▸ Isoniazid 10 mg/kg PO 3 times per week × 2 months PLUS ▸ Rifampicin 10 mg/kg PO qd OR ▸ Rifampicin 10 mg/kg PO 3 times per week × 2 months † For 2 months †† For 4 months; Adapted from Treatment of Tuberculosis: Guidelines. References