Chikungunya laboratory findings: Difference between revisions

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Revision as of 17:03, 13 June 2014

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Alejandro Lemor, M.D. [2], Alonso Alvarado, M.D. [3]

Overview

Laboratory findings of Chikungunya virus (CHIKV) infection include lymphopenia, thrombocytopenia, elevated creatinine, and elevated hepatic transaminases.

Laboratory Findings

Clinical laboratory findings can include lymphopenia, thrombocytopenia, elevated creatinine, and elevated hepatic transaminases.

References

External Links

CDC Chikungunya virus

@@ Line 2: / Line 2: @@
 {{Chikungunya}}
 {{CMG}}; {{AE}} {{AL}}, {{Alonso}}
+==Overview==
+Laboratory findings of Chikungunya virus (CHIKV) infection include [[lymphopenia]], [[thrombocytopenia]], elevated [[creatinine]], and elevated [[hepatic transaminases]].
 ==Laboratory Findings==
-* Clinical laboratory findings can include [[lymphopenia]], [[thrombocytopenia]], elevated [[creatinine]], and elevated [[hepatic transaminases]].
+Clinical laboratory findings can include [[lymphopenia]], [[thrombocytopenia]], elevated [[creatinine]], and elevated [[hepatic transaminases]].
-* Laboratory diagnosis is generally accomplished by testing serum or plasma to detect [[virus]], [[viral]] nucleic acid, or virus-specific [[immunoglobulin]] (Ig) M and neutralizing [[antibodies]].
-* [[Viral culture]] may detect [[virus]] in the first 3 days of illness; however, chikungunya [[virus]] should be handled under biosafety level (BSL) 3 conditions.
-* During the first 8 days of illness, chikungunya [[viral]] [[RNA]] can often be identified in serum.
-* Chikungunya [[virus]] [[antibodies]] normally develop toward the end of the first week of illness. Therefore, to definitively rule out the diagnosis, convalescent-phase samples should be obtained from patients whose acute-phase samples test negative.
-* Chikungunya [[virus]] testing is performed at CDC, a few state health departments, and one commercial laboratory.
-* Test results are normally available 4 to 14 days after specimen receipt.
-* Reporting times for test results may be longer during summer months when [[arbovirus]] activity increases.
-* Receipt of a hard copy of the results will take at least 2 weeks after testing is completed.
-* Initial [[serological testing]] will be performed using IgM-capture [[ELISA]] and IgG [[ELISA]]. If the initial results are positive, further confirmatory testing will be performed and it may delay the reporting of final results.
 ==References==
-* [http://www.cdc.gov/Chikungunya/index.html CDC Chikungunya virus]
 {{Reflist|2}}
+==External Links==
+* [http://www.cdc.gov/Chikungunya/index.html CDC Chikungunya virus]
 [[Category:Disease]]
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 [[Category:Togaviruses]]
 [[Category:Tropical disease]]
-[[Category:Needs overview]]
-{{WH}}
-{{WS}}