Dengue fever differential diagnosis: Difference between revisions
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/* Comparison between Chikungunya and Dengue Fever Adapted from Clin Infect Dis. (2009) 49(6):942-948.{{cite journal|last1=Staples|first1=J. Erin|last2=Breiman|first2=Robert F.|last3=Powers|first3=Ann M.|title=Chikungunya Fever: An Epidemiological Revi... |
/* Comparison between Chikungunya and Dengue Fever Adapted from Clin Infect Dis. (2009) 49(6):942-948.{{cite journal|last1=Staples|first1=J. Erin|last2=Breiman|first2=Robert F.|last3=Powers|first3=Ann M.|title=Chikungunya Fever: An Epidemiological Revi... |
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|+ '''''Clinical and laboratory findings of chikunguyna and dengue fever''''' | |+ '''''Clinical and laboratory findings of chikunguyna and dengue fever''''' | ||
! style="width: 180px;background: # | ! style="width: 180px;background: #4479BA"|{{fontcolor|#FFF| Clinical Findings}} | ||
! style="width: 120px;background: # | ! style="width: 120px;background: #4479BA"|{{fontcolor|#FFF| Chikungunya}} | ||
! style="width: 120px;background: # | ! style="width: 120px;background: #4479BA"|{{fontcolor|#FFF| Dengue Fever}} | ||
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| style="width: 120px;font-weight: bold;background: #DCDCDC"|[[Fever]] (>102°F or 39°C) | | style="width: 120px;font-weight: bold;background: #DCDCDC"|[[Fever]] (>102°F or 39°C) | ||
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| style="background: # | | style="background: #4479BA;font-weight: bold; text-align:center"|{{fontcolor|#FFF| Laboratory Findings}} | ||
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| style="width: 120px;font-weight: bold;background: #DCDCDC"|[[Hematocrit#Elevated hematocrit|Elevated hematocrit]] | | style="width: 120px;font-weight: bold;background: #DCDCDC"|[[Hematocrit#Elevated hematocrit|Elevated hematocrit]] | ||
Revision as of 14:31, 16 June 2014
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Overview
Dengue fever must be differentiated from other diseases that prevent with flu like symptoms fever, retro-orbital headache, fatigue, joint aches or arthralgias (joint aches), myalgias (muscle aches), nausea/vomiting, and lymphadenopathy (swollen lymph nodes). Diseases with similar symptoms include influenza, measles, rubella, malaria, and Yellow fever.
Diseases with Similar Symptoms
Comparison between Chikungunya and Dengue Fever Adapted from Clin Infect Dis. (2009) 49(6):942-948.[1]
- Chikungunya should be distinguished from dengue fever, which has the potential for much poorer clinical outcomes, including death. The two diseases can occur together in the same patient.
- Shock or severe hemorrhage is very rarely observed in Chikungunya.
- In Chikungunya the onset of the disease is more acute and the duration of fever is much shorter.
- A maculopapular rash is more frequent in Chikungunya, while petechia may occur in dengue fever.
- In Chikungunya the pain is much more pronounced and localized to the joints and tendons in comparison of dengue fever, which the pain is generalized.
| Clinical Findings | Chikungunya | Dengue Fever |
|---|---|---|
| Fever (>102°F or 39°C) | +++ | ++ |
| Headache | ++ | ++ |
| Rash | ++ | + |
| Arthralgias | +++ | +/– |
| Myalgias | + | ++ |
| Shock | — | +/– |
| Bleeding dyscrasias | +/– | ++ |
| Laboratory Findings | ||
| Elevated hematocrit | — | ++ |
| Leukopenia | ++ | +++ |
| Neutropenia | + | +++ |
| Lymphopenia | +++ | ++ |
| Thrombocytopenia | + | +++ |
| Mean frequency of symptoms from studies where the two diseases were directly compared among patient seeking care; +++ = 70-100% of patients; ++ = 40-69%; + = 10-39%; +/– = <10%; — = 0%[2][3] | ||
References
- ↑ Staples, J. Erin; Breiman, Robert F.; Powers, Ann M. (2009). "Chikungunya Fever: An Epidemiological Review of a Re‐Emerging Infectious Disease". Clinical Infectious Diseases. 49 (6): 942–948. doi:10.1086/605496. ISSN 1058-4838.
- ↑ S. Nimmannitya, S. B. Halstead, S. N. Cohen & M. R. Margiotta (1969). "Dengue and chikungunya virus infection in man in Thailand, 1962-1964. I. Observations on hospitalized patients with hemorrhagic fever". The American journal of tropical medicine and hygiene. 18 (6): 954–971. PMID 5355242. Unknown parameter
|month=ignored (help) - ↑ Patrick Hochedez, Ana Canestri, Amelie Guihot, Segolene Brichler, Francois Bricaire & Eric Caumes (2008). "Management of travelers with fever and exanthema, notably dengue and chikungunya infections". The American journal of tropical medicine and hygiene. 78 (5): 710–713. PMID 18458301. Unknown parameter
|month=ignored (help)