|
|
Line 1: |
Line 1: |
| ==Stage II==
| | | | |,|-|-|-|-|-|^|-|-|-|-|.| | | | | |}} |
| | | {{familytree | | | | F01 | | | | | | | | F02 | | | | | | | | | F03 | | | | | | | | | | | | | F01=Superior suculus tumor|F02=Preferred option: Surgery + pathological determination of microscopic residual tumor|F03=Neoadjuvant Chemotherapy <br>OR<br>Chemotherapy + radiation therapy}} |
| {{familytree/start}}
| | {{familytree | | | | |!| | | | | | | | | |!| | | | | | | | | | |!| | | | | | | | | | | | | | | |}} |
| {{familytree | | | | | | | | | | | | A01 | | | | | | | | | | | | | A01=<div style="float: left; text-align: left; width: 18em; padding:1em;">Has the [[tumor]] invaded adjacent structures, such as: chest walls, [[diaphragm]], [[phrenic nerve]], [[mediastinal pleura]], parietal [[pericardium]] or bronchial [[tumor]] smaller than 2 cm?</div>}}
| | {{familytree | | | | G01 | | | | | | | | G02 | | | | | | | | | G03 | | | | | | | | | | | | | | | G01=<div style="float: left; text-align: left; width: 14em; padding:1em;">Is the tumor larger than 7 cm or invaded adjacent structures (T3) with or without invasion of ipsilateral peribronchial or hiliar nodes (N1)? <br>OR<br> Has the tumor has estended to any of the following: |
| {{familytree | | | |,|-|-|-|-|-|-|-|-|^|-|-|-|-|-|-|-|.| | | |}}
| |
| {{familytree | | | B01 | | | | | | | | | | | | | | | B02 | | | | | | | | | | B01='''NO''' <br>
| |
| * T1a-b, 2a-b, N1<br>
| |
| * T2b, N0<br>
| |
| * T3 Tumor larger than 7 cm (not invasive)
| |
| |B02='''Yes''' <br>IIB: T3 (invasive [[tumor]])}}
| |
| {{familytree | | | |!| | | | | | | | | | | | | | | | |!| | | | | | | | | | |}} | |
| {{familytree | | | C01 | | | | | | | | | | | | | | | C02 | | | | | | | | | | C01=<div style="float: left; text-align: left; width: 14em; padding:1em;">'''Perform a pretreatment evaluation'''<br>
| |
| * If not done, perform [[pulmonary function tests]]<br>
| |
| * Perform [[bronchoscopy]] (if possible intraoperative)<br>
| |
| * Perform a pathological [[lymph node]] evaluation<br>
| |
| * If not done, order [[PET]] scan or [[CT scan]]
| |
| </div>|C02=<div style="float: left; text-align: left; width: 14em; padding:1em;">'''Perform a pretreatment evaluation'''<br>
| |
| * If not done, perform [[pulmonary function tests]]<br>
| |
| * Perform [[bronchoscopy]] (if possible intraoperative)<br>
| |
| * Perform a pathological [[lymph node]] evaluation<br>
| |
| * If not done, order [[PET]] scan or [[CT scan]]<br>
| |
| * Perform a [[Brain tumor MRI|brain MRI]]<br>
| |
| * Perform a spine [[MRI]] with thoracic inlet searching for superior suculus lesions and infiltration to the [[subclavian vessels]] or [[spine]]</div>}}
| |
| {{familytree | | | |!| | | | | | | | | | | | | | | | |!| | | | | | | | | | | | |}}
| |
| {{familytree | | | D01 | | | | | | | | | | | | | | | D02 | | | | | | | | | | | | | | |D01=Does the pathological evaluation showed positive disease in the mediastinal [[lymph nodes]]?|D02=What is the location of the [[tumor]]?}}
| |
| {{familytree | |,|-|^|-|.| | | | | | | | | | |,|-|-|-|^|-|-|-|.| | | | | | | |}}
| |
| {{familytree | E01 | | E02 | | | | | | | | | E03 | | | | | | E04 | | | | | | | | | | | | | E01=Yes|E02=No|E03=Superior suculus tumor|E04=Proximal airway <br>OR<br> Chest wall <br>OR<br> Mediastinum}}
| |
| {{familytree | |!| | | |!| | | | | | | | | | |!| | | | | | | | | | | | | | | | | |}} | |
| {{familytree | F01 | | F02 | | | | | | | | | F03 | | | | | | | | | | | | | | | | | | | | | | F01=[[Non small cell carcinoma of the lung#Stage III|Click here for the stage III treatment]]|F02=Is the tumor operable?|F03=Superior suculus tumor|F04=}}
| |
| {{familytree | | | |,|-|^|-|.| | | | | | | | |!| | | | | | | | | | | | | | | | | | | | | | | | | |}} | |
| {{familytree | | | G01 | | G02 | | | | | | | G03 | | | | | | | | | | | | | | | | | | | | | | | | | | | G01=Yes|G02=No|G03=<div style="float: left; text-align: left; width: 14em; padding:1em;">Is the tumor larger than 7 cm or invaded adjacent structures (T3) with or without invasion of ipsilateral peribronchial or hiliar nodes (N1)? <br>OR<br> Has the tumor has estended to any of the following:
| |
| * Carina<br> | | * Carina<br> |
| * Esophagus<br> | | * Esophagus<br> |
Line 37: |
Line 10: |
| * Mediastinum<br> | | * Mediastinum<br> |
| * Trachea<br> | | * Trachea<br> |
| * Nodules in a different ipsilateral lobe</div>}} | | * Nodules in a different ipsilateral lobe |
| {{familytree | | | |!| | | |!| | | | | |,|-|-|^|-|-|.| | | | | | | | | | | | | | | | | | | | | | | | |}} | | </div>|G02=Are margins from the surgical piece positive or negative for residual tumor?|G03=Perform surgery + pathological determination of residual tumor}} |
| {{familytree | | | H01 | | H02 | | | | H03 | | | | H02 | | | | | | | | | | | | | | | | | H01=Surgical resection + [[lymph node]] dissection|H02=Does the patient presents metastasis to ipsilateral peribronchial and/or hiliar nodesand intrapulmonar nodes (N1)?|H03=T3, N0-1|H04=T4}} | | {{familytree | |,|-|-|^|-|-|.| | | |,|-|-|^|-|-|.| | | | | | | |!| | | | | | | | | |}} |
| {{familytree | | | | | |,|-|^|-|.| | | |!| | | | | |!| | | | | | | | | | | | | | | | | | | | | | | | |}} | | {{familytree | H01 | | | | H02 | | H03 | | | | H04 | | | | | | H05 | | | | | | | | H01=T3, N0-1|H02=T4|H03=Negative (R0)|H04=Positive: Is the residual tumor microscopic (R1) or macroscopic (R2)|H05=Are margins from the surgical piece positive or negative for residual tumor?}} |
| {{familytree | | | | | I01 | | I02 | | I03 | | | | I04 | | | | | | | | | | | | | | | | | | | | | | | | | | | I01=Yes|I02=No|I03=Initiate neoadjuvant chemotherapy + radiation therapy|I04=Is the tumor resectable?}} | | {{familytree | |!| | | | | |!| | | |!| | | |,|-|^|-|.| | | |,|-|^|-|.| | | | | | | |}} |
| {{familytree | | | | | |!| | | |!| | | |!| | | |,|-|^|-|.| | | | | | | | | | | | | | | | | | | | | | | |}} | | {{familytree | I01 | | | | I02 | | I03 | | I04 | | I05 | | I06 | | I07 | | | | | | | | | | I01=Initiate neoadjuvant chemotherapy + radiation therapy|I02=Is the tumor resectable?|I03=Adjuvant chemotherapy|I04=Microscopic (R1)|I05=Macroscopic (R2)|I06=Negative (R1)|I07=Positive (R1-2)}} |
| {{familytree | | | | | J01 | | J02 | | J03 | | J04 | | J05 | | | | | | | | | | | | | | | | | | | | | | | | | | J01=[[Chemotherapy]] + [[radiation therapy]]|J02=Radiotherapy with stereotactic ablative radiotherapy<br>Adjuvant [[chemotherapy]] should be added for high-risk stages|J03=Surgery + adjuvant [[chemotherapy]]|J04=Yes|J05=No}} | | {{familytree | |!| | | |,|-|^|-|.| | | | | |!| | | |!| | | |!| | | |!| | | | | |}} |
| {{familytree | | | | | | | | | | | | | | | | | |!| | | |!| | | | | | | | | | | | | | | | | | | | | | | | | |}} | | {{familytree | J01 | | J02 | | J03 | | | | J04 | | J05 | | J06 | | J07 | | | | | | | | | | | | J01=Surgery + adjuvant [[chemotherapy]]|J02=Yes|J03=No|J04=Tumor resection + adjuvant chemotherapy<br>OR<br>Chemotherapy + radiotherapy|J05=Tumor resection + adjuvant chemotherapy<br>OR<br>Chemotherapy + radiotherapy|J06=Observation|J07=Tumor resection}} |
| {{familytree | | | | | | | | | | | | | | | | | K01 | | K02 | | | | | | | | | | | | | | | | | | | | | K01=Initiate neoadjuvant chemotherapy + radiation therapy|K02=Initiate definitive chemotherapy + radiation therapy}} | | {{familytree | | | | | |!| | | |!| | | | | | | | | | | | | | | | | | | | | | | | | |}} |
| {{familytree | | | | | | | | | | | | | | | | | |!| | | | | | | | | | | | | | | |}} | | {{familytree | | | | | K01 | | K02 | | | | | | | | | | | | | | | | | | | | | K01=Initiate neoadjuvant chemotherapy + radiation therapy|K02=Initiate definitive chemotherapy + radiation therapy}} |
| {{familytree | | | | | | | | | | | | | | | | | L01 | | | | | | | | | | | | | | | | L01=Perform a surgical evaluation: Is the tumor resectable?}} | | {{familytree | | | | | |!| | | | | | | | | | | | | | | |}} |
| {{familytree | | | | | | | | | | | | | | |,|-|-|^|-|-|.| | | | | | | |}} | | {{familytree | | | | | L01 | | | | | | | | | | | | | | | | L01=Perform a surgical evaluation: Is the tumor resectable?}} |
| {{familytree | | | | | | | | | | | | | | M01 | | | | M02 | | | | | | | | | | M01=Yes|M02=No}} | | {{familytree | | |,|-|-|^|-|-|.| | | | | | | |}} |
| {{familytree | | | | | | | | | | | | | | |!| | | | | |!| | | | | | | | | | |}} | | {{familytree | | M01 | | | | M02 | | | | | | | | | | M01=Yes|M02=No}} |
| {{familytree | | | | | | | | | | | | | | N01 | | | | N02 | | | | | | | | | | N01=Tumor extraction + adjuvant chemotherapy|N02=Definitive chemotherapy + radiation therapy}} | | {{familytree | | |!| | | | | |!| | | | | | | | | | |}} |
| | {{familytree | | N01 | | | | N02 | | | | | | | | | | N01=Tumor extraction + adjuvant chemotherapy|N02=Definitive chemotherapy + radiation therapy}} |
| {{familytree/end}} | | {{familytree/end}} |
| | |,|-|-|-|-|-|^|-|-|-|-|.| | | | | |}}
Superior suculus tumor
Preferred option: Surgery + pathological determination of microscopic residual tumor
Neoadjuvant Chemotherapy
OR
Chemotherapy + radiation therapy
Is the tumor larger than 7 cm or invaded adjacent structures (T3) with or without invasion of ipsilateral peribronchial or hiliar nodes (N1)?
OR
Has the tumor has estended to any of the following:
- Carina
- Esophagus
- Great vessels
- Heart
- Laryngeal nerve
- Mediastinum
- Trachea
- Nodules in a different ipsilateral lobe
Are margins from the surgical piece positive or negative for residual tumor?
Perform surgery + pathological determination of residual tumor
T3, N0-1
T4
Negative (R0)
Positive: Is the residual tumor microscopic (R1) or macroscopic (R2)
Are margins from the surgical piece positive or negative for residual tumor?
Initiate neoadjuvant chemotherapy + radiation therapy
Is the tumor resectable?
Adjuvant chemotherapy
Microscopic (R1)
Macroscopic (R2)
Negative (R1)
Positive (R1-2)
Surgery + adjuvant chemotherapy
Yes
No
Tumor resection + adjuvant chemotherapy
OR
Chemotherapy + radiotherapy
Tumor resection + adjuvant chemotherapy
OR
Chemotherapy + radiotherapy
Observation
Tumor resection
Initiate neoadjuvant chemotherapy + radiation therapy
Initiate definitive chemotherapy + radiation therapy
Perform a surgical evaluation: Is the tumor resectable?
Yes
No
Tumor extraction + adjuvant chemotherapy
Definitive chemotherapy + radiation therapy