Proparacaine

Proparacaine
Adult Indications & Dosage
Pediatric Indications & Dosage
Contraindications
Warnings & Precautions
Adverse Reactions
Drug Interactions
Use in Specific Populations
Administration & Monitoring
Overdosage
Pharmacology
Clinical Studies
How Supplied
Images
Patient Counseling Information
Precautions with Alcohol
Brand Names
Look-Alike Names

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Chetan Lokhande, M.B.B.S [2]

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Overview

Proparacaine is a local anesthetic that is FDA approved for the {{{indicationType}}} of anesthesia for procedures on eye.. Common adverse reactions include ophthalmic: conjunctival hemorrhage, corneal erosion, cycloplegia (rare ), passive conjunctival congestion.

Adult Indications and Dosage

FDA-Labeled Indications and Dosage (Adult)

There is limited information regarding Proparacaine FDA-Labeled Indications and Dosage (Adult) in the drug label.

Off-Label Use and Dosage (Adult)

Guideline-Supported Use

Trigeminal neuralgia

Non–Guideline-Supported Use

There is limited information regarding Off-Label Non–Guideline-Supported Use of Proparacaine in adult patients.

Pediatric Indications and Dosage

FDA-Labeled Indications and Dosage (Pediatric)

safety and effectiveness in pediatric patients have not been established; however the use of proparacaine HCl as a topical ophthalmic anesthetic agent in pediatric patients has been cited in the literature

Off-Label Use and Dosage (Pediatric)

Guideline-Supported Use

There is limited information regarding Off-Label Guideline-Supported Use of Proparacaine in pediatric patients.

Non–Guideline-Supported Use

There is limited information regarding Off-Label Non–Guideline-Supported Use of Proparacaine in pediatric patients.

Contraindications

ALCAINE® ophthalmic solution should be considered contraindicated in patients with known hypersensitivity to any of the ingredients of this preparation.

Warnings

NOT FOR INJECTION - FOR TOPICAL OPHTHALMIC USE ONLY. Prolonged use of a topical ocular anesthetic is not recommended. It may produce permanent corneal opacification with accompanying visual loss.

Adverse Reactions

Clinical Trials Experience

There is limited information regarding Proparacaine Clinical Trials Experience in the drug label.

Postmarketing Experience

There is limited information regarding Proparacaine Postmarketing Experience in the drug label.

Drug Interactions

There is limited information regarding Proparacaine Drug Interactions in the drug label.

Use in Specific Populations

Pregnancy

Pregnancy Category (FDA): There is no FDA guidance on usage of Proparacaine in women who are pregnant.
Pregnancy Category (AUS): There is no Australian Drug Evaluation Committee (ADEC) guidance on usage of Proparacaine in women who are pregnant.

Labor and Delivery

There is no FDA guidance on use of Proparacaine during labor and delivery.

Nursing Mothers

There is no FDA guidance on the use of Proparacaine in women who are nursing.

Pediatric Use

There is no FDA guidance on the use of Proparacaine in pediatric settings.

Geriatic Use

There is no FDA guidance on the use of Proparacaine in geriatric settings.

Gender

There is no FDA guidance on the use of Proparacaine with respect to specific gender populations.

Race

There is no FDA guidance on the use of Proparacaine with respect to specific racial populations.

Renal Impairment

There is no FDA guidance on the use of Proparacaine in patients with renal impairment.

Hepatic Impairment

There is no FDA guidance on the use of Proparacaine in patients with hepatic impairment.

Females of Reproductive Potential and Males

There is no FDA guidance on the use of Proparacaine in women of reproductive potentials and males.

Immunocompromised Patients

There is no FDA guidance one the use of Proparacaine in patients who are immunocompromised.

Administration and Monitoring

Administration

There is limited information regarding Proparacaine Administration in the drug label.

Monitoring

There is limited information regarding Proparacaine Monitoring in the drug label.

IV Compatibility

There is limited information regarding the compatibility of Proparacaine and IV administrations.

Overdosage

There is limited information regarding Proparacaine overdosage. If you suspect drug poisoning or overdose, please contact the National Poison Help hotline (1-800-222-1222) immediately.

Pharmacology

There is limited information regarding Proparacaine Pharmacology in the drug label.

Mechanism of Action

There is limited information regarding Proparacaine Mechanism of Action in the drug label.

Structure

There is limited information regarding Proparacaine Structure in the drug label.

Pharmacodynamics

There is limited information regarding Proparacaine Pharmacodynamics in the drug label.

Pharmacokinetics

There is limited information regarding Proparacaine Pharmacokinetics in the drug label.

Nonclinical Toxicology

There is limited information regarding Proparacaine Nonclinical Toxicology in the drug label.

Clinical Studies

There is limited information regarding Proparacaine Clinical Studies in the drug label.

How Supplied

There is limited information regarding Proparacaine How Supplied in the drug label.

Storage

There is limited information regarding Proparacaine Storage in the drug label.

Images

Drug Images

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Package and Label Display Panel

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Patient Counseling Information

There is limited information regarding Proparacaine Patient Counseling Information in the drug label.

Precautions with Alcohol

Alcohol-Proparacaine interaction has not been established. Talk to your doctor about the effects of taking alcohol with this medication.

Brand Names

There is limited information regarding Proparacaine Brand Names in the drug label.

Look-Alike Drug Names

There is limited information regarding Proparacaine Look-Alike Drug Names in the drug label.

Drug Shortage Status

Price

References

The contents of this FDA label are provided by the National Library of Medicine.