Leprosy other diagnostic studies: Difference between revisions
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===Smear test=== | ===Smear test=== | ||
May be obtained from any [[skin lesion]], from the [[nasal mucosa]] and/or the [[ear lobe]]. This test has a [[sensitivity]] of 50% and a [[specificity]] of 100%. After collection of the [[specimen]], in order to visualize the [[bacteria]], the ''Ziehl-Neelsen stain'' should be used.<ref name="EichelmannGonzález González2013">{{cite journal|last1=Eichelmann|first1=K.|last2=González González|first2=S.E.|last3=Salas-Alanis|first3=J.C.|last4=Ocampo-Candiani|first4=J.|title=Leprosy. An Update: Definition, Pathogenesis, Classification, Diagnosis, and Treatment|journal=Actas Dermo-Sifiliográficas (English Edition)|volume=104|issue=7|year=2013|pages=554–563|issn=15782190|doi=10.1016/j.adengl.2012.03.028}}</ref> | May be obtained from any [[skin lesion]], from the [[nasal mucosa]] and/or the [[ear lobe]]. This test has a [[sensitivity]] of 50% and a [[specificity]] of 100%. After collection of the [[specimen]], in order to visualize the [[bacteria]], the ''Ziehl-Neelsen stain'' should be used.<ref name="EichelmannGonzález González2013">{{cite journal|last1=Eichelmann|first1=K.|last2=González González|first2=S.E.|last3=Salas-Alanis|first3=J.C.|last4=Ocampo-Candiani|first4=J.|title=Leprosy. An Update: Definition, Pathogenesis, Classification, Diagnosis, and Treatment|journal=Actas Dermo-Sifiliográficas (English Edition)|volume=104|issue=7|year=2013|pages=554–563|issn=15782190|doi=10.1016/j.adengl.2012.03.028}}</ref><ref name="pmid7570870">{{cite journal| author=Hatta M, van Beers SM, Madjid B, Djumadi A, de Wit MY, Klatser PR| title=Distribution and persistence of Mycobacterium leprae nasal carriage among a population in which leprosy is endemic in Indonesia. | journal=Trans R Soc Trop Med Hyg | year= 1995 | volume= 89 | issue= 4 | pages= 381-5 | pmid=7570870 | doi= | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=7570870 }} </ref> | ||
===Skin Biopsy=== | ===Skin Biopsy=== | ||
Revision as of 05:42, 6 July 2014
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: João André Alves Silva, M.D. [2]
Overview
Other Diagnostic Studies
Smear test
May be obtained from any skin lesion, from the nasal mucosa and/or the ear lobe. This test has a sensitivity of 50% and a specificity of 100%. After collection of the specimen, in order to visualize the bacteria, the Ziehl-Neelsen stain should be used.[1][2]
Skin Biopsy
Lepromin Test
Serology
Polymerase Chain Reaction
References
- ↑ Eichelmann, K.; González González, S.E.; Salas-Alanis, J.C.; Ocampo-Candiani, J. (2013). "Leprosy. An Update: Definition, Pathogenesis, Classification, Diagnosis, and Treatment". Actas Dermo-Sifiliográficas (English Edition). 104 (7): 554–563. doi:10.1016/j.adengl.2012.03.028. ISSN 1578-2190.
- ↑ Hatta M, van Beers SM, Madjid B, Djumadi A, de Wit MY, Klatser PR (1995). "Distribution and persistence of Mycobacterium leprae nasal carriage among a population in which leprosy is endemic in Indonesia". Trans R Soc Trop Med Hyg. 89 (4): 381–5. PMID 7570870.