Sandbox JA: Difference between revisions
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Hospitalized patients for systemic [[anthrax]] should be immediately treated with a combination of [[broad-spectrum]] [[intravenous]] [[antimicrobial drug]] treatment pending confirmatory test results because any delay may prove fatal. | Hospitalized patients for systemic [[anthrax]] should be immediately treated with a combination of [[broad-spectrum]] [[intravenous]] [[antimicrobial drug]] treatment pending confirmatory test results because any delay may prove fatal. | ||
Because meningitis and hemorrhagic brain parenchymal infection was observed in ≤50% of cases, meningitis must be considered in all cases of systemic anthrax. | Because [[meningitis]] and hemorrhagic brain parenchymal [[infection]] was observed in ≤50% of cases, [[meningitis]] must be considered in all cases of systemic [[anthrax]]. Therefore [[antibiotics]] to treat possible [[meningitis]] must have good penetration of the [[central nervous system]] (CNS). | ||
Because of the presence of a [[spore]] form of [[Bacillus anthracis]], [[antibiotic therapy]] should be continued for 60 days to clear germinating organisms | |||
==Antimicrobial Treatment== | ==Antimicrobial Treatment== | ||
Revision as of 14:37, 17 July 2014
Medical Therapy
The treatment of anthrax infection includes antimicrobial and antitoxin agents. This treatment and postexposure prophylaxis differs from other bacterial infections because:
- Production of toxin
- Potential antibiotic resistance
- Frequent occurrence of meningitis
- Presence of latent spores must be taken into account when selecting postexposure prophylaxis or a combination of antibiotics for treatment of anthrax.
Hospitalized patients for systemic anthrax should be immediately treated with a combination of broad-spectrum intravenous antimicrobial drug treatment pending confirmatory test results because any delay may prove fatal.
Because meningitis and hemorrhagic brain parenchymal infection was observed in ≤50% of cases, meningitis must be considered in all cases of systemic anthrax. Therefore antibiotics to treat possible meningitis must have good penetration of the central nervous system (CNS).
Because of the presence of a spore form of Bacillus anthracis, antibiotic therapy should be continued for 60 days to clear germinating organisms