Gitoformate: Difference between revisions
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==Overview== | ==Overview== | ||
'''Gitoformate''' ([[International Nonproprietary Name|INN]], or '''pentaformylgitoxin''', trade name '''Dynocard''') is a [[cardiac glycoside]], a type of drug that can be used in the treatment of [[congestive heart failure]] and [[cardiac arrhythmia]] (irregular heartbeat). | '''Gitoformate''' ([[International Nonproprietary Name|INN]], or '''pentaformylgitoxin''', trade name '''Dynocard''') is a [[cardiac glycoside]], a type of drug that can be used in the treatment of [[congestive heart failure]] and [[cardiac arrhythmia]] (irregular heartbeat). Produced by Madaus, it is not available in the US, and does not seem to be available in Europe either. | ||
==Chemistry== | ==Chemistry== | ||
Latest revision as of 21:34, 23 July 2014
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| E number | {{#property:P628}} |
| ECHA InfoCard | {{#property:P2566}}Lua error in Module:EditAtWikidata at line 36: attempt to index field 'wikibase' (a nil value). |
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| Formula | C46H64O19 |
| Molar mass | 920.989 g/mol |
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Ongoing Trials on Gitoformate at Clinical Trials.gov Clinical Trials on Gitoformate at Google
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US National Guidelines Clearinghouse on Gitoformate
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Patient resources on Gitoformate Discussion groups on Gitoformate Patient Handouts on Gitoformate Directions to Hospitals Treating Gitoformate Risk calculators and risk factors for Gitoformate
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Overview
Gitoformate (INN, or pentaformylgitoxin, trade name Dynocard) is a cardiac glycoside, a type of drug that can be used in the treatment of congestive heart failure and cardiac arrhythmia (irregular heartbeat). Produced by Madaus, it is not available in the US, and does not seem to be available in Europe either.
Chemistry
Gitoformate is a derivative of the glycoside gitoxin, with five of the six free hydroxyl groups formylated, one on the aglycon and four on the sugar.[1][2] Gitoxin, a cardiac glycoside from the Woolly Foxglove (Digitalis lanata), has an aglycon of the cardenolide type named gitoxigenin, which is also the aglycon of lanatoside B, another Digitalis lanata glycoside.[3]
References
- ↑ PMID 6542412 (PMID 6542412)
Citation will be completed automatically in a few minutes. Jump the queue or expand by hand - ↑ Template:PubChem
- ↑ William O. Foye,Thomas L. Lemke, David A. Williams. Foye's principles of medicinal chemistry. p. 699. ISBN 978-0-7817-6879-5.
- Pages with script errors
- Pages with incomplete PMID references
- CS1 maint: Uses authors parameter
- E number from Wikidata
- ECHA InfoCard ID from Wikidata
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- Drugs with no legal status
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- Cardiac glycosides
- Cardiovascular Drugs
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