Malaria laboratory findings: Difference between revisions
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* Specific diagnostic tests for malaria | * Specific diagnostic tests for malaria | ||
* Laboratory workup | * Laboratory workup | ||
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, , and and increases in lactic dehydrogenase may be marked with large P. falciparum parasite burdens. | |||
Microcytosis may be seen in patients from malaria-endemic areas but is often due to iron deficiency or thalassemia. | |||
Leukocyte counts may be high, normal, or low. | |||
Platelet counts may be normal or slightly low but have been observed to be <70,000/μL in P. falciparum infection398 and occasion- ally in P. vivax infection. | |||
Sodium may be slightly low, possibly owing to syndrome of inappropriate antidiuretic hormone, excessive vomiting, or urinary losses. | |||
Acidemia (pH less than 7.35), acidosis (bicarbonate < 15 mmol/L), and lactate levels >5 mmol/L can be seen in severe P. falciparum malaria (see later). | |||
Some degree of renal impairment is common in falciparum malaria and may be associated with increased creatinine, proteinuria, and hemoglobinuria. | |||
Serum glucose is often low in children with falciparum malaria, but it is commonly normal in adults. | |||
In children with severe falciparum malaria, bacteremia/sepsis may be present at the time of initial clinical evalua-tion and blood cultures may be positive.402,403 | |||
Revision as of 20:04, 24 July 2014
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Overview
Laboratory Findings
Whenever possible, the diagnosis of malaria should always be confirmed by laboratory tests. These should include:
- Specific diagnostic tests for malaria
- Laboratory workup
Laboratory Findings
The table below displays the nonspecific laboratory abnormalities associated with Ebola infection, including:[1]
| Test | Findings |
|---|---|
| Complete Blood Count count | Decreased Hemoglobin Decreased Hematocrit Decreased Haptoglobin Microcytosis |
| White blood cell count | Increased or Decreased Leukocyte Count |
| Biochemistry | Hypoglycemia Increased LDH Possible Hyponatremia Acidosis: High Lactate; Low Bicarbonate |
| Coagulation | Thrombocytopenia |
| Liver function tests | Raised [[]] [[]] [[]] [[]] |
| Urinalysis | Proteinuria Hemoglobinuria |
References
- ↑ Feldmann H, Geisbert TW (2011). "Ebola haemorrhagic fever". Lancet. 377 (9768): 849–62. doi:10.1016/S0140-6736(10)60667-8. PMC 3406178. PMID 21084112.