Malaria laboratory findings: Difference between revisions

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Revision as of 20:09, 24 July 2014

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Overview

Laboratory Findings

Whenever possible, the diagnosis of malaria should always be confirmed by laboratory tests. These should include:

Specific diagnostic tests for malaria
Laboratory workup

Laboratory Findings

The table below displays the nonspecific laboratory abnormalities associated with Ebola infection, including:^[1]

**Laboratory findings**
Test	Findings
Complete Blood Count	Decreased Hemoglobin Decreased Hematocrit Microcytosis Decreased Haptoglobin
White blood cell count	Increased or Decreased Leukocyte Count
Biochemistry	Hypoglycemia Increased Creatinine Increased LDH Possible Hyponatremia Acidosis: High Lactate; Low Bicarbonate
Coagulation	Thrombocytopenia
Urinalysis	Proteinuria Hemoglobinuria

References

↑ Feldmann H, Geisbert TW (2011). "Ebola haemorrhagic fever". Lancet. 377 (9768): 849–62. doi:10.1016/S0140-6736(10)60667-8. PMC 3406178. PMID 21084112.CS1 maint: PMC format (link)

Template:WH Template:WS

[pmid21084112-1] Feldmann H, Geisbert TW (2011). "Ebola haemorrhagic fever". Lancet. 377 (9768): 849–62. doi:10.1016/S0140-6736(10)60667-8. PMC 3406178. PMID 21084112.CS1 maint: PMC format (link)

[1]

@@ Line 22: / Line 22: @@
 ! style="width: 200px; background: #4479BA; text-align: center;"| {{fontcolor|#FFF|Findings}}
 |-
-| style="background: #F5F5F5; padding: 5px; text-align: center;"| '''[[Complete Blood Count]] count'''
+| style="background: #F5F5F5; padding: 5px; text-align: center;"| '''[[Complete Blood Count]]'''
-| style="background: #DCDCDC; padding: 5px;"| Decreased [[Hemoglobin]]<br>Decreased [[Hematocrit]]<br>Decreased [[Haptoglobin]]<br>[[Microcytosis]]
+| style="background: #DCDCDC; padding: 5px;"| Decreased [[Hemoglobin]]<br>Decreased [[Hematocrit]]<br>[[Microcytosis]]<br>Decreased [[Haptoglobin]]
 |-
 | style="background: #F5F5F5; padding: 5px; text-align: center;"| '''[[White blood cell]] count'''
@@ Line 29: / Line 29: @@
 |-
 | style="background: #F5F5F5; padding: 5px; text-align: center;"| '''[[Biochemistry]]'''
-| style="background: #DCDCDC; padding: 5px;"| [[Hypoglycemia]]<br>Increased [[LDH]]<br>Possible [[Hyponatremia]]<br> Acidosis: High [[Lactate]]; Low [[Bicarbonate]]
+| style="background: #DCDCDC; padding: 5px;"| [[Hypoglycemia]]<br> Increased [[Creatinine]]<br>Increased [[LDH]]<br>Possible [[Hyponatremia]]<br> Acidosis: High [[Lactate]]; Low [[Bicarbonate]]
 |-
 | style="background: #F5F5F5; padding: 5px; text-align: center;"| '''[[Coagulation]]'''
 | style="background: #DCDCDC; padding: 5px;"| [[Thrombocytopenia]]
-|-
-| style="background: #F5F5F5; padding: 5px; text-align: center;"| '''[[Liver function tests]]'''
-| style="background: #DCDCDC; padding: 5px;"| Raised [[]]<br>[[]]<br>[[]]<br>[[]]
 |-
 | style="background: #F5F5F5; padding: 5px; text-align: center;"| '''[[Urinalysis]]'''
@@ Line 42: / Line 39: @@
 <!--
-, , and and increases in lactic dehydrogenase may be marked with large P. falciparum parasite burdens.
-Microcytosis may be seen in patients from malaria-endemic areas but is often due to iron deficiency or thalassemia.
-Leukocyte counts may be high, normal, or low.
-Platelet counts may be normal or slightly low but have been observed to be <70,000/μL in P. falciparum infection398 and occasion- ally in P. vivax infection.
-Sodium may be slightly low, possibly owing to syndrome of inappropriate antidiuretic hormone, excessive vomiting, or urinary losses.
-Acidemia (pH less than 7.35), acidosis (bicarbonate < 15 mmol/L), and lactate levels >5 mmol/L can be seen in severe P. falciparum malaria (see later).
-Some degree of renal impairment is common in falciparum malaria and may be associated with increased creatinine, proteinuria, and hemoglobinuria.
-Serum glucose is often low in children with falciparum malaria, but it is commonly normal in adults.
-In children with severe falciparum malaria, bacteremia/sepsis may be present at the time of initial clinical evalua-tion and blood cultures may be positive.402,403

Malaria laboratory findings: Difference between revisions

Revision as of 20:09, 24 July 2014

Overview

Laboratory Findings

Laboratory Findings

References

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