Celiprolol: Difference between revisions
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A recent clinical trial has suggested a use for this medication in the prevention of vascular complications of a rare inherited disease called vascular [[Ehlers–Danlos syndrome]]. This study demonstrated decreased incidence of arterial rupture or dissection (a specific type of arterial rupture in which the layers of the vessel separate prior to complete failure of the artery wall).<ref>{{cite journal | author = Ong K-T et al. | title = Effect of celiprolol on prevention of cardiovascular events in vascular Ehlers-Danlos syndrome: a prospective randomised, open, blinded-endpoints trial | journal = Lancet | year = 2010 | doi=10.1016/S0140-6736(10)60960-9 | volume = 376 | issue = 9751 | pages = 1476–1484 | pmid = 20825986}}</ref> | A recent clinical trial has suggested a use for this medication in the prevention of vascular complications of a rare inherited disease called vascular [[Ehlers–Danlos syndrome]]. This study demonstrated decreased incidence of arterial rupture or dissection (a specific type of arterial rupture in which the layers of the vessel separate prior to complete failure of the artery wall).<ref>{{cite journal | author = Ong K-T et al. | title = Effect of celiprolol on prevention of cardiovascular events in vascular Ehlers-Danlos syndrome: a prospective randomised, open, blinded-endpoints trial | journal = Lancet | year = 2010 | doi=10.1016/S0140-6736(10)60960-9 | volume = 376 | issue = 9751 | pages = 1476–1484 | pmid = 20825986}}</ref> | ||
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==External Links== | ==External Links== | ||
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[[Category:Drug]] | [[Category:Drug]] | ||
[[Category:Beta blockers]] | [[Category:Beta blockers]] | ||
[[Category:Antihypertensive agents]] | |||
Revision as of 02:23, 25 July 2014
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| E number | {{#property:P628}} |
| ECHA InfoCard | {{#property:P2566}}Lua error in Module:EditAtWikidata at line 36: attempt to index field 'wikibase' (a nil value). |
| Chemical and physical data | |
| Formula | C20H33N3O4 |
| Molar mass | 379.49 g/mol |
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Overview
Celiprolol (brand names Cardem, Selectol, Celipres, Celipro, Celol, Cordiax, Dilanorm) is a medication in the class of beta blockers, used in the treatment of high blood pressure. It has a unique pharmacology: it is a selective β1 receptor antagonist, but a β2 receptor partial agonist. It is also a weak α2 receptor antagonist.
A recent clinical trial has suggested a use for this medication in the prevention of vascular complications of a rare inherited disease called vascular Ehlers–Danlos syndrome. This study demonstrated decreased incidence of arterial rupture or dissection (a specific type of arterial rupture in which the layers of the vessel separate prior to complete failure of the artery wall).[1]
References
- ↑ Ong K-T; et al. (2010). "Effect of celiprolol on prevention of cardiovascular events in vascular Ehlers-Danlos syndrome: a prospective randomised, open, blinded-endpoints trial". Lancet. 376 (9751): 1476–1484. doi:10.1016/S0140-6736(10)60960-9. PMID 20825986.
External Links
- Selectol Summary of Product Characteristics (from the IPHA Medicines Compendium)
- Celiprolol data sheet for New Zealand
- Pages with script errors
- CS1 maint: Explicit use of et al.
- E number from Wikidata
- ECHA InfoCard ID from Wikidata
- Chemical articles with unknown parameter in Infobox drug
- Articles without EBI source
- Chemical pages without ChemSpiderID
- Chemical pages without DrugBank identifier
- Articles without KEGG source
- Articles without InChI source
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- Drugs with no legal status
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- Cardiovascular Drugs
- Drug
- Beta blockers
- Antihypertensive agents