Yersinia pestis infection medical therapy: Difference between revisions
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{{Yersinia pestis infection}} | {{Yersinia pestis infection}} | ||
{{CMG}}; '''Assistant Editors-In-Chief:''' [[Esther Lee, M.A.]] | {{CMG}}; '''Assistant Editors-In-Chief:''' [[Esther Lee, M.A.]]; {{JS}} | ||
==Overview== | ==Overview== | ||
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==Medical Therapy== | ==Medical Therapy== | ||
When a [[diagnosis]] of human plague is suspected on [[clinical]] and [[epidemiological]] grounds, appropriate specimens for [[diagnosis]] should be obtained immediately and the patient should be started on specific [[antibiotic|antimicrobial therapy]] without waiting for a definitive answer from the laboratory. | |||
Suspect plague patients with evidence of pneumonia should be placed in isolation, and managed under respiratory droplet precautions. | |||
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Persons who have been in close contact with a plague patient, particularly a patient with plague pneumonia, should be identified and evaluated. The [[U.S. Public Health Service]] requires that all cases of suspected plague be reported immediately to local and state health departments and that the diagnosis be confirmed by [[CDC]]. As required by the International Health Regulations, [[CDC]] reports all U.S. plague cases to the [[World Health Organization]]. Early treatment of [[pneumonic plague]] is essential. To prevent a high risk of death, antibiotics should be given within 24 hours of the first symptoms. Several types of [[antibiotics]] are effective for curing the disease and for preventing it. | Persons who have been in close contact with a plague patient, particularly a patient with plague pneumonia, should be identified and evaluated. The [[U.S. Public Health Service]] requires that all cases of suspected plague be reported immediately to local and state health departments and that the diagnosis be confirmed by [[CDC]]. As required by the International Health Regulations, [[CDC]] reports all U.S. plague cases to the [[World Health Organization]]. Early treatment of [[pneumonic plague]] is essential. To prevent a high risk of death, antibiotics should be given within 24 hours of the first symptoms. Several types of [[antibiotics]] are effective for curing the disease and for preventing it. | ||
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Antibiotic treatment for 7 days will protect people who have had direct, close contact with infected patients. Wearing a close-fitting surgical mask also protects against infection. However, antibiotic treatment alone is insufficient for some patients, who may also require circulatory, ventilator, or [[kidney|renal]] support. | Antibiotic treatment for 7 days will protect people who have had direct, close contact with infected patients. Wearing a close-fitting surgical mask also protects against infection. However, antibiotic treatment alone is insufficient for some patients, who may also require circulatory, ventilator, or [[kidney|renal]] support. | ||
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Revision as of 13:39, 25 July 2014
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Yersinia pestis infection Microchapters |
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Differentiating Yersinia Pestis Infection from other Diseases |
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Diagnosis |
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Treatment |
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Case Studies |
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Yersinia pestis infection medical therapy On the Web |
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American Roentgen Ray Society Images of Yersinia pestis infection medical therapy |
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Risk calculators and risk factors for Yersinia pestis infection medical therapy |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Assistant Editors-In-Chief: Esther Lee, M.A.; João André Alves Silva, M.D. [2]
Overview
According to treatment experts, a patient diagnosed with suspected plague should be hospitalized and medically isolated. Laboratory tests should be done, including blood cultures for plague bacteria and microscopic examination of lymph gland, blood, and sputum samples. Antibiotic treatment should begin as soon as possible after laboratory specimens are taken. Effective antibiotics are streptomycin, gentamicin (used when streptomycin is not available), tetracyclines and chloramphenicol. (used for critically ill patients, or rarely for suspected neuro-involvement)
Medical Therapy
When a diagnosis of human plague is suspected on clinical and epidemiological grounds, appropriate specimens for diagnosis should be obtained immediately and the patient should be started on specific antimicrobial therapy without waiting for a definitive answer from the laboratory.
Suspect plague patients with evidence of pneumonia should be placed in isolation, and managed under respiratory droplet precautions.
References