Yersinia pestis infection primary prevention: Difference between revisions
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{{Yersinia pestis infection}} | {{Yersinia pestis infection}} | ||
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==Overview== | ==Overview== | ||
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==Hospital Precautions== | ==Hospital Precautions== | ||
Standard patient-care precautions should be applied to management of all suspected plague patients. These include prescribed procedures for: | Standard patient-care precautions should be applied to management of all suspected plague patients. These include prescribed procedures for: | ||
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Persons who must be present in an area where a plague outbreak is occurring can protect themselves for 2 to 3 weeks by taking [[antibiotics]]. The preferred antibiotics for prophylaxis against plague are the [[tetracyclines]] or the [[sulfonamides]]. | Persons who must be present in an area where a plague outbreak is occurring can protect themselves for 2 to 3 weeks by taking [[antibiotics]]. The preferred antibiotics for prophylaxis against plague are the [[tetracyclines]] or the [[sulfonamides]]. | ||
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==References== | ==References== | ||
{{reflist|2}} | {{reflist|2}} |
Revision as of 17:29, 25 July 2014
Yersinia pestis infection Microchapters |
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: João André Alves Silva, M.D. [2]
Overview
A plague vaccine is not currently available for use in the United States. Preventive measures are directed to home, work, and recreational settings where the risk of acquiring plague is high.
Prophylactic Therapy
Post-exposure prophylaxis is indicated in persons who, in the previous six days:
- Have had close contact with pneumonic plague patients
- Are likely to have been exposed to Y. pestis-infected fleas
- Are likely to have had direct contact with body fluids or tissues of a Y. pestis-infected mammal
- Were exposed during a laboratory accident to known infectious materials
The preferred antimicrobials for preventive or abortive therapy are the tetracyclines, chloramphenicol, or one of the effective sulfonamides.[1]
True prophylaxis, meaning the administration of an antibiotic prior to exposure, may be indicated when persons must be present for short periods in plague-active areas under circumstances in which exposure to plague sources (fleas, pneumonic cases) is difficult or impossible to prevent.[1]
persons with known exposure to plague, such as close contact with a pneumonic plague patient or direct contact with infected body fluids or tissues. Duration of post-exposure prophylaxis to prevent plague is 7 days. The recommended antibiotic regimens for PEP are as follows:
▸ Click on the following categories to expand treatment regimens.[1]
Plague Treatment ▸ Adult Patients ▸ Children ▸ Pregnant Patients |
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