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==Historical Perspective==
==Historical Perspective==
[[Hepatitis A virus]] was first identified in 1973. It was classified as a separate disease from other types of [[hepatitis]] during World War II. However, its true [[prevalence]] and route of [[transmission]] would only be recognized later.<ref name="pmid7876643    [">{{cite journal| author=Melnick JL| title=History and epidemiology of hepatitis A virus. | journal=J Infect Dis | year= 1995 | volume= 171 Suppl 1 | issue=  | pages= S2-8 | pmid=7876643    [ | doi= | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=7876643  }} </ref>
* [[Hepatitis A virus]] was first identified in 1973. It was classified as a separate disease from other types of [[hepatitis]] during World War II. However, its true [[prevalence]] and route of [[transmission]] would only be recognized later.<ref name="pmid7876643    [">{{cite journal| author=Melnick JL| title=History and epidemiology of hepatitis A virus. | journal=J Infect Dis | year= 1995 | volume= 171 Suppl 1 | issue=  | pages= S2-8 | pmid=7876643    [ | doi= | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=7876643  }} </ref>


The [[incidence]] of [[hepatitis A]] varies among eras, countries and even cities within the same country. In recent years it has been noted a shift in prevalence, what was once a disease more prevalent in children, is today predominant in adults.
* During 1995-1996, the Food and Drug Administration (FDA) approved the inactivated hepatitis A vaccines. Consequently, [[hepatitis A]] became a disease that was not only common but also vaccine-preventable.
 
The resistance of the [[virus]] allows it to survive in urban sewage. Accordingly, [[outbreaks]] of the disease occur in overcrowded areas where there is poor sanitation. Improvements made throughout the years have decreased the [[incidence]] of the [[infection]] in new infants, which has led to an increasing number of adults with [[hepatitis A]]. [[Hepatitis A]] [[epidemiology]] in the United States has changed with licensure of [[hepatitis A]] [[vaccine]] and implementation of national ACIP recommendations for its use.
 
During 1995-1996, the Food and Drug Administration (FDA) approved the inactivated hepatitis A vaccines. Consequently, [[hepatitis A]] became a disease that was not only common but also vaccine-preventable.
 
Today [[transmission]] of the [[virus]] through [[blood]] is rare, however, some risk groups such as IV drug users and their care takers are still [[infected]] by this route.<ref name="pmid7876643    [">{{cite journal| author=Melnick JL| title=History and epidemiology of hepatitis A virus. | journal=J Infect Dis | year= 1995 | volume= 171 Suppl 1 | issue=  | pages= S2-8 | pmid=7876643    [ | doi= | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=7876643  }} </ref>


==References==
==References==

Revision as of 01:36, 30 July 2014

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Overview

The hepatitis A virus was first identified in 1973. With the FDA approval of the vaccine, during 1995-1996, hepatitis A became a disease that was not only common, but also vaccine-preventable.

Historical Perspective

  • During 1995-1996, the Food and Drug Administration (FDA) approved the inactivated hepatitis A vaccines. Consequently, hepatitis A became a disease that was not only common but also vaccine-preventable.

References

  1. Melnick JL (1995). "History and epidemiology of hepatitis A virus". J Infect Dis. 171 Suppl 1: S2–8. PMID [ 7876643 [ Check |pmid= value (help).

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