Hepatitis D medical therapy: Difference between revisions

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==Medical Therapy==
==Medical Therapy==
The goal of treatment in hepatitis D is the clearance of the HDV and of the hepatitis B helper virus. The complexity of the treatment resides in the need to address two viruses, and in the simplicity of the HDV, which limits the number of targets for therapeutic agents.
The goal of treatment in hepatitis D is the clearance of the HDV and of the hepatitis B helper virus. The complexity of the treatment resides in the need to address two viruses, and in the simplicity of the HDV, which limits the number of targets for therapeutic agents.
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There is no specific available treatment. For persons with severe [[hepatitis]], only supportive care is given. The treatment of chronic active [[hepatitis B]] and coexistent hepatitis D infection with [[alpha interferon]] would be done only after consultation and referral to a gastroenterologist.<ref>Center for Substance Abuse Treatment. Screening for Infectious Diseases Among Substance Abusers. Rockville (MD): Substance Abuse and Mental Health Services Administration (US); 1993. (Treatment Improvement Protocol (TIP) Series, No. 6.) Chapter 15 - Viral Hepatitis D.</ref>
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Monitoring HDV RNA and serological levels of [[HBsAg]] may help in management of these patients.<ref name="pmid17591028">{{cite journal |author=Manesis EK, Schina M, Le Gal F, Agelopoulou O, Papaioannou C, Kalligeros C, Arseniou V, Manolakopoulos S, Hadziyannis ES, Gault E, Koskinas J, Papatheodoridis G, Archimandritis AJ |title=Quantitative analysis of hepatitis D virus RNA and hepatitis B surface antigen serum levels in chronic delta hepatitis improves treatment monitoring |journal=[[Antiviral Therapy]] |volume=12 |issue=3 |pages=381–8 |year=2007 |pmid=17591028 |doi= |url= |accessdate=2012-03-16}}</ref>
Follow-up for 6months may be recommended in these patients to evaluate for the development of chronic HBV and HDV infection.


==References==
==References==

Revision as of 15:44, 6 August 2014

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Varun Kumar, M.B.B.S. [2]; João André Alves Silva, M.D. [3] Jolanta Marszalek, M.D. [4]

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Medical Therapy

The goal of treatment in hepatitis D is the clearance of the HDV and of the hepatitis B helper virus. The complexity of the treatment resides in the need to address two viruses, and in the simplicity of the HDV, which limits the number of targets for therapeutic agents.

References

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