Stockholm Ischemic Heart Disease Study: Difference between revisions
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==Overview== | ==Overview== | ||
Stockholm Ischemic Heart Disease study is a randomized open label trial that assessed the effect of clofibrate and nicotinic acid vs placebo on ischemic heart disease mortality. | The Stockholm Ischemic Heart Disease study is a randomized open label trial that assessed the effect of [[clofibrate]] and [[nicotinic acid]] vs placebo on ischemic heart disease mortality. | ||
==Study Description== | ==Study Description== | ||
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| '''Allocation'''||Randomized | | '''Allocation'''||Randomized | ||
|- | |- | ||
| '''Endpoint'''||Ischemic heart disease | | '''Endpoint'''||Ischemic heart disease mortality | ||
|- | |- | ||
| '''Masking'''||Open label | | '''Masking'''||Open label | ||
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==Publications== | ==Publications== | ||
The Stockholm Ischemic Heart Disease study revealed a 36% decrease in ischemic heart disease mortality among patients ho recieved the treatment vs control, an effect most likely related to the [[triglyceride]]s plasma concentration particularly among patients with a triglyceride level higher than 1.5 mmol/l and those who had a decrease in the serum triglyceride by at least 30%. | |||
==References== | ==References== |
Revision as of 02:55, 19 August 2014
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Rim Halaby, M.D. [2]
Overview
The Stockholm Ischemic Heart Disease study is a randomized open label trial that assessed the effect of clofibrate and nicotinic acid vs placebo on ischemic heart disease mortality.
Study Description
Study Description | |
Study Design | |
Allocation | Randomized |
Endpoint | Ischemic heart disease mortality |
Masking | Open label |
Study Details | |
Primary Purpose | |
Condition | Survivors of a myocardial infarction |
Study Arms | Clofibrate and nicotinic acid Control |
Population Size | 555 subjects |
Publications
The Stockholm Ischemic Heart Disease study revealed a 36% decrease in ischemic heart disease mortality among patients ho recieved the treatment vs control, an effect most likely related to the triglycerides plasma concentration particularly among patients with a triglyceride level higher than 1.5 mmol/l and those who had a decrease in the serum triglyceride by at least 30%.