Mitral regurgitation epidemiology and demographics: Difference between revisions
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==Overview== | ==Overview== | ||
Mitral regurgitation (MR) is one of the most common [[valvular disease]]s in the general population, ranking first among valvular regurgitation abnormailities. The prevalence of MR of a severity equal to or more than mild was reported in The Framingham Heart Study as 19.0% in men and 19.1% in women. The prevalence of MR increases with age.<ref name="pmid10190406">{{cite journal| author=Singh JP, Evans JC, Levy D, Larson MG, Freed LA, Fuller DL et al.| title=Prevalence and clinical determinants of mitral, tricuspid, and aortic regurgitation (the Framingham Heart Study) | journal=Am J Cardiol | year= 1999 | volume= 83 | issue= 6 | pages= 897-902 | pmid=10190406 | doi= | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=10190406 }} </ref> | |||
==Prevalence== | ==Prevalence== | ||
Revision as of 17:54, 8 September 2014
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Varun Kumar, M.B.B.S.; Lakshmi Gopalakrishnan, M.B.B.S.
Overview
Mitral regurgitation (MR) is one of the most common valvular diseases in the general population, ranking first among valvular regurgitation abnormailities. The prevalence of MR of a severity equal to or more than mild was reported in The Framingham Heart Study as 19.0% in men and 19.1% in women. The prevalence of MR increases with age.[1]
Prevalence
The Framingham Heart Study, a prospective epidemiologic study, evaluated the prevalence and severity of MR and other valvular diseases by color Doppler examinations in 1,696 men and 1,893 women. The study revealed that MR is the most common valvular regurgitation in the general population, followed by tricuspid regurgitation and then aortic regurgitation. The prevalence of MR (with a severity ranging from trace to ≥ moderate regurgitation) was 87.7% in men and 91.5% in women. When trace regurgitation is excluded, the prevalence of MR of a severity ≥ mild was 19.0% in men and 19.1% in women. The elevated prevalence of trace regurgitation can be a normal finding related to an artifact or an anatomic characteristic of the closure of the mitral valve.[1]
Age
The prevalence of MR increases with age. MR is one of the most common valvular heart disease in the elderly. Shown below are tables depicting the prevalence of MR by age and severity in men and women according the results of the Framingham Heart Study.[1]
| Severity of MR | Prevalence of MR by age in men | ||||
| 26-29 | 40-49 | 50-59 | 60-69 | 70-83 | |
| No MR (%) | 14.4 | 13.3 | 11.3 | 12.7 | 9.0 |
| Trace (%) | 76.7 | 72.9 | 74.6 | 60.3 | 51.7 |
| Mild (%) | 8.9 | 13.5 | 12.5 | 24.6 | 28.1 |
| Moderate or severe (%) | 0 | 0.3 | 1.6 | 2.4 | 11.2 |
| Severity of MR | Prevalence of MR by age in women | ||||
| 26-29 | 40-49 | 50-59 | 60-69 | 70-83 | |
| No MR (%) | 14.0 | 8.6 | 9.0 | 7.2 | 5.6 |
| Trace (%) | 76.3 | 75 | 74 | 66.5 | 70.8 |
| Mild (%) | 9.7 | 15.5 | 16 | 24 | 23.6 |
| Moderate or severe (%) | 0 | 0.9 | 1 | 2.3 | 0 |
Gender
Overall, mitral regurgitation affects both males and females equally. However, there are some minor differences when age is considered.